Compound shows promise as vaccine-like drug for preventing type 1 diabetes
... million people in the United States and is on the rise worldwide. The synthetic compound, called ISO-1, appears to work by blocking a pathway involved in inflammation. If successful as a vaccine-like drug, it could ultimately save lives, reduce health care costs and help prediabetic people avoid a lifeti...Injuries to children show definite patterns
...dual drop in the preschool years and then a steady rise again with age. Injuries such as dislocations, sprains, and fractures increase with age. Children with a first injury before age two were four times more likely to have repeat injuries than children whose first injury occurred after two. About 18...American Thoracic Society Journal news tips for April 2004 (first issue)
...e exacerbations. The researchers found that small rise in two different sizes of particulate matter (PM2....ore patient exacerbations. A 10 parts per billion rise in ozone was associated with a 10 percent increase in exacerbations. (CF is a common inherited dise...Researchers to pinpoint relationship between obesity-associated diabetes and heart disease
The rise in obesity, now at epidemic levels in the United States, has been matched by a rise in diabetes, a deadly combination that increases heart disease risk by two to five times. Research h...Study supports new theory for nicotine's protective effect against neurodegenerative disorders
...des, the microglia may become hyperactive and give rise to chronic inflammation that further aggravates the destruction of brain cells. "In those at risk for Alzheimer's and other neurodegenerative diseases, nicotine may act much like the neurotransmitter acetylcholine. It may send signals to hel...C-reactive proteins do not predict early osteoarthritis
...n or infections, and their levels in the blood can rise dramatically in many chronic disease states. While previous studies by other researchers have suggested that elevated levels of C-reactive protein may be a predictive marker for disease, they did not take into account the role of weight or ethnicity,...Dairy, moderate fat, carbohydrate intakes reduce obesity in young teens
...ascular Disease Epidemiology and Prevention. "The rise in obesity in the nation's young people may be partly due to fewer home-cooked meals, more calorie-dense foods, and more takeout and prepackaged dinners," said Lynn L. Moore, D.Sc., associate professor of medicine at Boston University School of Medic...Painkiller linked to rise in overdose deaths
...lief may inadvertently be the cause of an alarming rise in deaths related to the drug in the US. Forensic science experts fear that a huge increase in methadone prescriptions is feeding the black market and encouraging abuse. In 2001, the Food and Drug Administration's MedWatch programme recorded 61 met...Physician assistant profession ranked third fastest-growing profession
...obs to grow by 49 percent by 2012, as PAs continue rise up list of fastest-growing U.S. professions Alexandria, VA March 2, 2004 The physician assistant (PA) profession is projected to become the third fastest-growing occupation in the U.S. between 2002 and 2012, according to employment projections re...Research news from Tufts University, Friedman School of Nutrition Science and Policy: March 2004
...ber of people with Type 2 diabetes has been on the rise in the United States and an estimated 24% of adults in the US have the metabolic syndrome that often precedes Type 2 diabetes and cardiovascular disease. New research from Tufts University shows that people who eat three or more servings per day of w...Sleep shortage takes toll on middle schoolers
...ly led to declines in self-esteem and grades and a rise in depressive symptoms. Girls had a harder time than boys in getting enough sleep, she says. They got more sleep than boys as they started middle school, possibly because girls enter puberty earlier, creating a greater need for sleep. Levels of sleep...Study provides answers for childbirth after C-section
...challenged. Landon said there has been an apparent rise in the frequency of reported uterine rupture among pregnant women, with associated maternal and perinatal risk. The rate of VBAC fell by more than half to 12.7 percent in 2002. In past studies of VBAC and cesarean sections, the magnitude of risks has...... pulses can trigger suicide in the cells that give rise to fat cells, possibly opening up a new way of treating obesity, Beebe speculates. And Vernier is working with doctors at the Cedars-Sinai Medical Center in Los Angeles to see if nanopulses can speed up the healing of wounds. "We do see an effect, b...The long view: Understanding why cancer strikes late
...rates of breast, prostate, colon, and lung cancers rise with age. Older people do indeed get these cancers much more often, but the increase with age slows down later in life. In the new work, Frank asks how the passage through the benign early stages of cancer would cause the increase in cancer inciden...Reduced risk for developing type 2 diabetes recommended for inclusion in Xenical's European label
...arned of a global epidemic of diabetes caused by a rise in overweight and obesity. There are currently 120-140 million people worldwide with type 2 diabetes, and if trends continue, this number is predicted to double in the next 25 years.2 More than 90% of all people with type 2 diabetes are overweight or...Risk for lowered cognitive performance is greater in people at high risk for stroke
...al and functional changes in the brain that do not rise to the level of clinical detection. Very recent evidence from a brain imaging study with a large subset of Framingham Offspring who also participated in our study indicated that abnormal brain atrophy is related both to higher risk of stroke and poor...Funding and distribution of inappropriate drugs add to rising global childhood malaria deaths
...imethamine, or the combination of these drugs. The rise of drug resistance is the leading cause of the global increase in childhood malarial deaths. Recent evidence suggests that a new, highly effective treatment known as artemisinin-class combination therapy (ACT) offers more hope for treating malaria in...The BESST way to judge IVF success
... argue that such "league tables" contribute to the rise in multiple births, because they encourage clinics to boost birth rates by transferring more embryos (New Scientist, 13 July 2002, p 4). So Healy's team is instead proposing a universal measure based on the birth of single, full-term babies. In pri...Drug company fees for FDA reviews havent accelerated approvals, study finds
... The researchers found that this prolonged, steady rise in review staff, not any particular aspect of PDUFA, was responsible for the drop in approval times. In all, the average review time for a drug dropped by 3.3 months for every 100 additional FDA staff hired. If FDA staffing had stayed constant at 19...Combined drug therapy prevents progression of prostate enlargement
...se was defined by one of the following: a 4-point rise in the American Urological Association's symptom severity score, urinary retention (inability to urinate), recurrent urinary tract infection or urinary incontinence. Finasteride, a 5 alpha-reductase inhibitor, and doxazosin, an alpha-1 receptor bl...