University of Pittsburgh imaging agent study suggests breakthrough in Alzheimer's research
...e telltale plaque deposits they believe are at the root of the disease. Alzheimer's is a debilitating brain disease that affects memory and cognitive function in approximately 4 million Americans today and, if unchecked, will strike as many as 14 million during the next 50 years. The distinguishing factor...Aromatase inhibitors: A promising new treatment for endometriosis
...osis is like fuel for fire. We need to attack the root problem the aromatase in order to eliminate this cycle, halt the local production of estrogen and treat women with this disease." Dr. Bulun evaluated 10 patients with moderate to severe endometriosis, all previously treated both medically and ...Widespread nerve fiber damage in brains of patients with multiple sclerosis associated with fatigue
...e fiber) damage associated with MS may also be the root cause of the fatigue reported by patients with MS. Maria Carmela Tartaglia, B.Sc., M.D., of Montreal Neurological Institute and Hospital, Quebec, and colleagues examined the relationship between nerve fiber damage in the brains of patients with MS ...Cord blood cells proven to differentiate into heart muscle and brain cells
...dence to prove that cord blood stem cells were the root of a cure. Now, the Duke team has dissected heart tissue to confirm the presence of donor stem cells in heart tissue. Moreover, they showed that donor stem cells had differentiated into heart muscle cells called myocytes, which then produced the crit...Poor diet and physical inactivity may soon overtake tobacco as leading cause of death in U.S.
...possible," they write. "Refining insights into the root causes of illness and injury, presenting those insights in a fashion that can motivate and guide effective action, and marshaling the effort to monitor the results of these actions will require steady improvement in the knowledge base. National leade...A new hypothesis about Alzheimer's disease
...e the hypothesis that these metabolites may be the root cause of Alzheimer's, Kelly and his colleagues examined the post-mortem brains of Alzheimer's patients and compared these to age-matched controls. They found evidence of atheronals in the brains of both the Alzheimer's patients and the control subj...Computerized prescriber order entry systems may have limited impact on patient harm
...rs occur, because it is imperative to identify the root cause of the problems before you can fix them. We wanted to recognize the errors with the greatest potential for patient harm and then design our CPOE system and/or clinical decision support to target those areas first," said Dr. Noskin. "Sometimes...Newly-described route to cancer solves a mystery in lung cancer
...at myristoylation has been fingered as a potential root cause of cancer, say the researchers. "Most genetic mechanisms for causing cancer include mutations that make gene products overactive or inactive. That's not the case here," says the study's senior author, Lin Ji, Ph.D., assistant professor in the D...Spartans go to the Olympics not on the field, but with the field
...l sciences have been working for months designing root zones and recommending appropriate grasses that are tough enough to withstand the rigors of soccer and field events, as well as the scorching Greek summers. Bermuda grass is the trick, Rogers said. Graduate student Matt Anderson traveled to Greec...Combination of erection pill and testosterone gel may benefit men who fail treatment with pill alone
...low testosterone is a contributing factor. If the root cause is low testosterone, sildenafil alone won't fix the problem." It is estimated that four to five million American men have low testosterone. Furthermore, low testosterone, also called hypogonadism or "low T," affects about one in 10 men between...New imaging technique may help reduce risk of heart attacks, strokes
...al sequence of events is still unclear, but at the root appears to be myeloperoxidase (MPO), an enzyme secreted by white blood cells infectious bacteria. But studies have found MPO seems to exert another, unwanted effect in arterial plaques. A breakdown product of MPO triggers the release of an enzyme tha...Major overhaul needed in end-of life care for patients with dementia
...f hospice care. "The nature of the illness is the root cause of the problem," said Greg Sachs, M.D., professor of medicine, section chief of geriatrics at the University of Chicago and first author of the study. "Our health care system is oriented toward treatment of acute illness but dementia produces ...Major overhaul needed in end-of life care for patients with dementia
...ce care. "The nature of the illness is the root cause of the problem," said Greg Sachs, M.D., professor of medicine, section chief of geriatrics at the University of Chicago and first author of the study. "Our health care system is oriented toward treatment of acute illness but dementia produces ...Several new techniques show promise for spinal cord repair
... upper limb of adult, female rats at the C8 dorsal root entry zone (DREZ) . Seven days later, the C8 dorsal root was crushed three times with #3 jeweler's forceps. Using a subset of 12 animals, the investigators m...Patients who are intubated prior to hospital arrival fare worse find Pitt researchers
...ients with severe head injury and to determine the root cause of why patients who receive out-of-hospital intubation fare worse than those who receive intubation at the hospital. Collaborating with lead authors Henry Wang, M.D., M.P.H., and Dr. Yealy were Andrew B. Peitzman, M.D.; P. David Adelson, M.D.;...Carrot component reduces cancer risk
...n to eat carrots - a compound found in the popular root vegetable has been found to have an effect on the development of cancer. A team of researchers, from the University of Newcastle upon Tyne in England and Denmark, found the natural pesticide falcarinol reduced the risk of cancer developing in rats by...USC dental researchers develop first test for predicting cavities in children
...be replaced with larger fillings, often leading to root canals, crowns and even tooth loss. That is why stopping the formation of cavities is so important, Denny said. "It's the initial cavity or caries that we're worried about," he said. "If we can prevent that, then we prevent this whole lifelong proce...When the brain, not the ears, goes hard of hearing
...se the feedback system is failing." To get to the root of the feedback problem, Frisina's neuroscience team is investigating the possible role of a breakdown in calcium regulation in the brain stem, throwing askew the way nerve cells talk to each other and possibly resulting in a toxic buildup of calcium...Potential treatment for Fragile X Syndrome demonstrated in fruit fly model
...ues surmised that mGluR overactivity may be at the root of many of the Fragile X symptoms. Using such drugs as lithium chloride and others, known as antagonists, that block mGluR's activity, the team tested to see if the drugs could rescue any of the observed behavioral and memory defects observed in the ...Even mild depression increases long-term mortality in heart failure
... including age, marriage, cardiac function and the root cause of the heart failure," Jiang said. Jiang said that many cardiologists or primary care physicians who treat heart failure patients may be unfamiliar with, or too busy to include, a psychological assessment into their practice. However, she point...