Successful Cancer Therapy May Doom Later Treatments To Failure
...to the development ofresistance -- when successive rounds of chemotherapeutic agents allow impervious mutants to gain a foothold. "You can't talk about multidrug resistance if you can't get the drugs into the tumor," says Jain. He believes there is another explanation for such disappointing results: chemoth...A combination of targeted therapies may be needed to keep prostate cancer at bay
...the mice developed resistant tumors after multiple rounds of treatment with ZD1839. After the mice stopped responding to treatment with ZD1839, the investigators wanted to determine whether different targeted drugs would combat resistance. First, they gave the mice who had developed resistant tumors a dru...Experimental pill found to improve symptoms in patients with non-small-cell lung cancer
...all-cell lung cancer who had undergone two or more rounds of chemotherapy. One group of patients received 2...se disease had progressed after at least two prior rounds of chemotherapy. Among these patients, 102 were randomly selected to receive 250 mg of ZD 1839 each...UCLA Jonsson Cancer Center researchers study ways to prevent tobacco-related bladder cancer
...dder cancer. The bladder cancer-prevention program rounds out the Jonsson Cancer Center's effort to better prevent and treat smoking-related cancers. UCLA researchers also are studying ways to prevent lung cancer. The popular anti-inflammatory drug Celebrex is being tested in people at high risk of developi...Brain imaging study reveals interplay of thought and emotion in economic decisions
...d the results from 19 subjects, who each played 10 rounds of the game with different proposers, they found that the activity of the emotion area exceeded that of the deliberative area in cases when the subjects rejected the offers. The reverse was true when they accepted offers. "It is not only telling us t...Rejection really hurts, UCLA psychologists find
... elevated activity during both the first and third rounds in the anterior cingulate. Located in the center of the brain, the cingulate has been implicated in generating the adverse experience of physical pain. "Rationally we can say being excluded doesn't matter, but rejection of any form still appears to ......lectronically linked to a physician to augment the rounds physicians make routinely to check on their patients. Vaguely resembling a human torso, in a Star Wars "R2D2" sort of way, the robot sports a computer screen for a head, a video camera for eyes and a speaker for a mouth. It "walks," in a manner of s...'Sit-down' rounds improve outcomes for kidney dialysis patients
...atients treated at clinics that conducted sit-down rounds at least once a month were more likely to have hea...Nephrology and available online Nov. 19. Sit-down rounds provide an opportunity for the patient care team to thoroughly assess progress, address problems and...Moving admitted ER patients into inpatient beds faster could significantly increase hospital revenue
...tients (especially on weekdays), physicians making rounds late in the day, or inadequate turnover of beds by housekeeping. While the study found chest pain patients' length of stay in the emergency department had no association with their health outcome, total hospital length of stay or health system cost o...Residual tumor cells are a barrier to targeted cancer therapeutics
...o simulate the treatment of patients with multiple rounds of a molecularly targeted therapy, the investigators found that nearly every tumor eventually progressed to a state that was no longer dependent upon MYC for growth. With these experiments, Chodosh and colleagues demonstrated that small numbers of br...Study: Young adults can be motivated to eat fruits, veggies
... of two years, Nitzke and her team conducted three rounds of interviews with more than 1,200 low-income young adults between the ages of 18 and 24. In between interviews, some study participants received phone calls and materials that were tailored to their readiness to make dietary changes. Others received...... investor received $20 during the first of the 10 rounds of the game. That person decided how much money to give the other subject. That sum was then tripled. The other subject, 1,500 miles away, decided how much of the money he or she kept and how much he or she left for the other subject. Each interactio...