Exemestane beats tamoxifen in first phase III head to head trial in advanced breast cancer
...oidal and non-steroidal aromatase inhibitors (AIs) safely be combined with chemotherapy; what effect does exemestane have on the bones, and can resistance to treatment be delayed by use of other drugs such as HER pathway blockers? Numerous trials were underway looking at AIs as adjuvant treatment. It was po...Drug for erectile dysfunction appears safe for some men with congestive heart failure
...with congestive heart failure appear to be able to safely take sildenafil, a drug used to treat erectile dysfunction (ED), if they are not taking nitrates to treat their heart condition, and have no evidence of myocardial ischemia, according to an article in the March 8 issue of The Archives of Internal Med...Improving treatment of medulloblastoma, a common childhood brain tumor
... hormones. Therefore, identifying patients who can safely undergo a milder course of treatment can help minimize these lasting effects of therapy. Ultimately, guiding treatment using knowledge of tumor biology could increase survival rates while reducing the severity of toxic side-effects. The study was le...Study shows positive results for novel, patient-controlled transdermal system (PCTS)...
... a prescription pain medication that has been used safely and effectively for more than 30 years. If approved by the U.S. Food and Drug Administration (FDA), E-TRANS Fentanyl HCl PCTS will be utilized in the management of acute pain requiring opioid analgesia. "It is important that we explore new approac...Corkscrew device retrieves clots, quickly reverses stroke damage
...to momentarily stop blood flow so the clots can be safely removed. Starkman added that the retrieval procedure can only be performed by a highly trained team at specialized centers. The results presented today are based on 114 patients from 25 centers, (average age 70, 46 percent women), whose average Nat...Change in social policies could reduce high rate of depression in men who have sex with men
... of depression among MSM. We believe that one can safely assume that the much higher rate of depression in MSM is directly related in some fashion to the larger social issue of homophobia," says Mills. The study analyzed data collected in the Urban Men's Health Study, a household survey conducted between N...Low free testosterone levels linked to Alzheimer's disease in older men
...f hormonal therapy or any other intervention could safely prevent AD," she said. Dr. Resnick, Scott Moffat, Ph.D., and their colleagues evaluated the testosterone levels of 574 men, ages 32 to 87, who participated in the Baltimore Longitudinal Study of Aging (BLSA)**. The investigators examined free and t...'Ding' concussions require removal from the game
...ve shown that, generally, an athlete can fully and safely recover from a mild concussion as long as the brain has had time to heal before returning to contact sports. Once an athlete sustains an initial concussion, however, he or she is more susceptible to further, more serious brain damage, worsening of sy...Normal aging versus Alzheimer's disease and the potential for prevention
...ys of maintaining general brain health that can be safely recommended to everyone and could have a real impact on helping people maintain the brain's repair mechanisms, resilience and responsiveness," said Dr. Albert. Dr. Albert emphasized that while nothing had been proven so far, there are a number of in...Doctors at Northwestern Memorial are studying next generation surgery for back pain sufferers
...ficial discs will have the long-term durability to safely provide increased range of motion and less strain on the adjacent discs than spinal fusion. Northwestern Memorial Hospital is one of approximately 30 sites around the country testing the Maverick artificial disc made from cobalt-chrome alloy. Curre...Persistently abnormal liver function tests: Marker of occult hepatitis C?
...h occult HCV infection may be more easily and more safely identified by obtaining and testing blood cells rather than liver cells. In an accompanying editorial, Herv Lerat, MD, and F. Blaine Hollinger, MD, of Baylor College of Medicine, Houston, commented that the distribution of hepatic enzyme elevatio...'Duct Busters' team travels to perform newborn heart surgery at regional hospitals
...he Children's Hospital of Philadelphia. "If we can safely bring our services to them, then medically and socially it is the right thing to do." The team credits the safety and effectiveness of this approach to the experience of a multidisciplinary team and extensive preoperative assessment, planning and ...USP's hospital medication error report supports key patient safety goals
...istributed, prescribed, dispensed and administered safely to minimize the risk of injury to patients. "USP's data clearly demonstrate the need to improve patient safety through renewed efforts to prevent patient misidentification, miscommunication between caregivers, errors in administration of high-risk m...Warfarin effective for stroke prevention in patients with atrial fibrillation
The blood thinner warfarin can be safely and effectively used to prevent stroke in patients with atrial fibrillation, according to an article in the November 26 issue of The Journal of the American Medical Association (JAMA). According to background information in the article, multiple rand...NIAID Ebola vaccine enters human trial
... adds, "because it employs new technology known to safely stimulate broad immune responses." Besides assessing the vaccine's safety, researchers will also examine the volunteers' blood to look for signs of immune system reaction to the vaccine. Ultimately, the scientists envision this vaccine as the first i...Fosrenol shows significant reduction in serum phosphate in Chinese end-stage kidney disease patients
...potential to reduce high phosphate levels quickly, safely and effectively to levels that comply with the new K/DOQI guidelines. These data suggest that lanthanum carbonate, when approved and available, may provide substantial clinical benefits to people on dialysis," said Prof. Wu-Chang Yang. Sixty perce...Panel: Clinical use of embryonic stem cells jeopardized by Bush's policy on federal funding
...e what it values more -- ensuring that all benefit safely and fairly from advances in stem cell science, or protecting embryonic human life." Faden also notes that the panel did not decide whether a national advisory committee should be established to oversee future clinical trials with ES cells. "That rema...University of Pittsburgh receives grant for research on cancer and aging
...blems that can make cancer more difficult to treat safely and effectively. Our program will address these challenges by performing laboratory and clinical research studies on the effects of aging on cancer development and progression; developing ways to characterize the nature, severity and likely effects o...New TB vaccine shows promise in HIV infection
... strategy to immunize persons with HIV against TB, safely and effectively," said von Reyn. In a "back to the future" approach, the investigators revived a strategy used successfully prior to BCG: administration of killed vaccines against TB. The DMS-led team dusted off the concept to employ a multiple dos...NIAMS researchers collaborate to produce targeted immunosuppressant drug
...ermine if this drug could be used successfully and safely in humans. Immunosuppressant drugs, which inhibit the body's immune response, are given to prevent the body from rejecting transplanted organs, and are also used to treat autoimmune diseases such as lupus, rheumatoid arthritis, eczema and psoriasis. ...