Hopkins begins human trials with donor adult stem cells to repair muscle damaged from heart attack
... animal studies, that more than 75 percent of dead scar tissue disappeared after therapy, which produced mostly healthy, normal-looking heart tissue and left only a small trace of the heart attack. The Phase I study is being conducted at Hopkins, with support from Baltimore-based Osiris Therapeutics, whic...New technique shows promise for improved straightening of crooked nose
...smooth, and strong to reduce the effects of future scar contracture or trauma."...Study finds drug eluting stents as effective as vascular brachytherapy in preventing restenosis
...to keep blood vessels open. But despite stenting, scar tissue can form to create new blockages -- a process called in-stent restenosis (ISR). At present, vascular brachytherapy (catheter-based delivery of intracoronary radiation) is the only therapeutic modality proven to effectively reduce in-stent rest...Schepens scientists regenerate optic nerve for the first time
...generation. The second lock, they theorized, was a scar on the brain created shortly after birth by "glial... the brain, one of which is to create this kind of scar tissue). The researchers believed that the scar puts up a physical as well as molecular barrier to r...Jefferson scientists uncover potential trigger of diabetic kidney disease
... a study to evaluate how a new medicine may reduce scar tissue in damaged kidneys. "The goal of this study...ound the TGF-beta stimulates overproduction of the scar tissue in the kidneys of diabetic patients and prevents normal kidney function. The new drug, pirfen...Brain synapse formation linked to proteins, Stanford study finds
...xcessive synapses. Barres suggested that the glial scar might have originally triggered the additional synapses to form. Learning more about how glia trigger synapse formation could help prevent the disabling condition. Co-first authors on this paper were Karen Christopherson, PhD, postdoctoral fellow, a...New method to fix cleft palate shows promise in Mayo Clinic lab study
...se. The current repair method also may shorten and scar the soft palate, which can impair speech. The study of this method of cleft palate repair was conducted on 10 adult hounds, due to similarities to the human mouth. Two hounds served as study controls and had a surgically created cleft palate, but ...Spinal repair pioneer to speak in NY on 20th Jan
...selves. They remain piled up in a great scar. The scar has the value of holding the flood water back but forms an impenetrable barrier to the cars. "The way out of the impasse came from the discovery that there is one part of the nervous system, and only one, in which nerve fibres are in a state of conti...Risks from labor after prior cesarean delivery low, study reports
...esarean delivery. Uterine rupture occurs when the scar in the uterine muscle opens. The rupture may result in part or all of the baby and perhaps the placenta leaving the uterus, which may cause fetal heart rate abnormalities and perhaps fetal death. A more severe, or catastrophic, rupture may result in...Drug-eluting stents adopted quickly, with early disparities
...hemotherapeutic agent that limits the formation of scar tissue inside the artery. So far, clinical trials have shown that these new stents can reduce the restenosis rate to single digits from the 20 to 30 percent rate of the older stents. The first drug-eluting stent received FDA approval in April, 2003. ...Loyola study shows drug-coated stent induces less inflammation than bare metal stent
...ith the earlier stents, tissue cells grew too much scar tissue, renarrowing the artery that the stent was supposed to widen," said Leya, director, interventional cardiology and director, cardiac catherization lab at Loyola. Leya said that the FDA-approved stent produces immediate results. "It is espec...Stem cell therapy effectively treats heart attacks in animals
...levels existing prior to infarction. Indeed, dead scar tissue nearly disappeared after therapy, which produced mostly healthy, normal-looking heart tissue and left only a small trace of the heart attack, the researchers said. In contrast, for the seven animals in the control group that did not receive th...Several new techniques show promise for spinal cord repair
...ase the enzyme that breaks down a component of the scar that forms after spinal cord injury. Dennis Stelzn...cluding myelin (nerve covering) components and the scar tissue that forms after spinal cord injury, including the molecule chondroitin sulfate. "We hypothe...Minimally invasive surgery for heart rhythm abnormality proven effective
... placed incisions in the atria. The slits generate scar tissues that serve as barriers, trapping abnormal ...quency variation of the Cox maze procedure creates scar tissues that similarly block abnormal impulses responsible for atrial fibrillation. Damiano's team ...Plastic surgeons honor 'Patients of Courage' overcoming difficult obstacles, inspiring others
...rs later, she developed an aggressive tumor on the scar from her surgery. Although surgeons were able to remove the tumor, Driskell had a severely deformed abdomen that required multiple reconstructive plastic surgeries. Despite a long battle with her insurance company, including several denials, Driskell...Denver physician patents minimally invasive technology for hair transplantation surgery
...e sides or back of the head, resulting in a linear scar and a lengthy healing time. A newer, less invasive technique called Follicular Unit Extraction (FUE) uses a small instrument to remove single follicular units of hair. Although much less invasive than traditional donor harvesting, FUE can be time c...Envisat Symposium report day 3: Satellites supporting Kyoto - our future is in our forests
...ontrast, making May to July the best time for burn scar detection. These scientific studies show the potential of Earth Observation to support the forest reporting mandatory for advanced nation signatories to Kyoto; France has already used ASAR data to map forest coverage across the whole of French Guian...Chemists honor 'Heroes' for biotechnology achievements in health
...he macula. These vessels leak and eventually cause scar tissue, which destroys central vision. Some 200,000 Americans lose their vision every year from wet AMD. Visudyne is first injected into the patient's arm and then activated by shining a non-thermal laser light into the eye. Schering-Plough Corpor...Hebrew University one of 25 institutions involved in new European Vascular Genomics Network
... (the atherosclerotic plaque is an accumulation of scar tissue, blood cells, cholesterol, and other fatty substances into the artery wall; the buildup of plaque narrows the arteries and slows the flow of blood); 3. Therapeutic angiogenesis that opens avenues for novel treatment of heart disease meant to i...Cancer gene therapy news backgrounder: New ideas fuel next generation gene therapy research
... Anderson scientists found only empty cavities and scar tissue where human glioma tumors had once been. The therapy, known as Delta-24-RGD, had moved like waves throughout the brains of the mice, killing the cancer while leaving normal tissue intact. While the treatment employs an adenovirus, it does not ...