Schizophrenia-Like Behavior In Rats Blocked Via Glutamate
...ontal cortex. Affecting about 1 percent of adults, schizophrenia is the most chronic anddisabling mental illness. It typically begins as a psychotic episode in earlyadulthood, with devastating hallucinations, delusions, social withdrawal,blunted emotionality, and loss of social and personal care skills. A newgene...... neurons -- can reverse symptoms of a rat model of schizophrenia withoutapparent side effects, according to a Yale ...attention that are thought to parallel symptoms of schizophrenia inhumans. By using a drug that stimulates a specific type of glutamate receptor,the Yale researcher......sesinclude Parkinson's and Alzheimer's, as well as schizophrenia and ALS (LouGehrig's disease). In this study, Trodat was intravenously injected into rats. Trodat displayedspecific brain uptake in the rats' striatal region of the brain where dopamineneurons are concentrated. The study's findings strongly support...PITT Researchers Demonstrate Human Brain's Natural Mechanism For Guarding Against Errors
...he hope ofunderstanding its role in disorders like schizophrenia and depression." The work was conducted in association with the Center for the NeuralBasis of Cognition, a joint project of the University of Pittsburgh and CarnegieMellon University, and UPMC Health System's Western Psychiatric Institute and...