International breast cancer prevention study launches in the United States and Canada
... a steroidal aromatase inactivator, which means it selectively targets and irreversibly binds to the aromatase enzyme, which is required to produce estrogen. Without estrogen, breast cancer cells cannot survive. Exemestane is well tolerated and the side effects associated with the treatment are generally predi...Newly discovered pathway might help in design of cancer drugs
...stics and exposed it to long wavelength light that selectively switches on the DNA damage process. He said that the synthetic DNA is very similar to that which is produced when cells are exposed to radiation, with one exception: Greenberg's team's DNA was damaged at only one place on its chain, allowing the res...Routine dental panoramic X-rays not necessary, study shows
...utinely, called the panoramic X-ray, could be used selectively in some cases instead of as a routine diagnostic tool. Results of the study were presented today (March 11, 2005) at the International Association on Dental Research General Session, being held in Baltimore. "You can't assess cavities or gum diseas...New substance that improves the photodetection of bladder cancer gains market approval
...of Hexvix is applied to bladder tissue where it is selectively metabolized by cancer cells into a fluorescent compound. About a half hour later, the physician examines the inside of the bladder with a cystoscope, using blue light instead of white light. With the help of a filter placed on the camera, the fluores...Plant derivative attacks the roots of leukemia
...y drug called cytarabine. The result: parthenolide selectively killed the leukemia cells while sparing the normal cells better than cytarabine. Scientists believe parthenolide might also make cancer more sensitive to other anti-tumor agents. And, the UR group was able to demonstrate the molecular pathways that ...Investigational transplant drug effectively preserves kidneys while avoiding toxic side effects
...maceutical Research Institute, developed LEA29Y to selectively block the second of two cellular signals (co-stimulatory signals) the body needs to trigger an immune response. Blocking this co-stimulatory signal prevents organ rejection while allowing the body to continue fighting other infections. Following i...Newly identified gene cluster on mouse X chromosome provides insights into fertility
...reproductive homeobox X-linked (or Rhox) genes, is selectively expressed in male and female reproductive tissues ...nd that all the genes in the Rhox gene cluster are selectively expressed in male and female reproductive tissue in adult mice," Wilkinson says. "This suggests the ...NYU psychology researchers show how attention enhances visual perception
...er for Neural Science, found that attending to, or selectively processing information from a given location witho...nded stimulus--that is, to the information that is selectively processed at a given location. In this study, the researchers presented observers with two patches ...New way to block pox shows promise in lab study
...that they too might be defeated through drugs that selectively block erb-B. While typically causing only mild disease, cytomegalovirus can be very serious in the young or in persons with compromised immune systems. In a commentary accompanying the research article, Dr. Fauci and NIAID co-author Mark Challberg, P...First US kidney cancer vaccine trial underway at Columbia
...mulates all T-cells, the Trovax Vaccine helps IL-2 selectively target only cancer cells, reducing side effects by not targeting and unnecessarily killing normal cells. Trovax has shown promise in similar trials conducted in Europe in colon cancer. About Trovax Trovax belongs to a class of medicines called a v...Holidays, birthdays and postponement of cancer deaths
..., and may reflect a general tendency for people to selectively remember positive events. He says while some may feel the findings of the study take away the hope of a prolonged life, others may see them in a different light. "I think all of us may know or have heard of someone 'hanging on' through the h...Novartis announces collaboration with Bayer for EMSELEX
...e antagonist (M3 SRA) oral treatment that works by selectively inhibiting the M3 receptor, the primary mediator of detrusor contraction, whilst sparing the M1 and M2 receptors that are located in various body organs, including the brain and heart. EMSELEX has been shown to effectively reduce the number of weekly...Updated adjuvant data presented at SABCS show 30 percent reduction in recurrence
... a steroidal aromatase inactivator, which means it selectively targets and irreversibly binds to the aromatase enzyme, which is required to produce estrogen. Without estrogen, breast cancer cells cannot survive. Exemestane is well tolerated and the side effects associated with the treatment are generally predic...Lab study: Protein delivered via genetically engineered virus slowed glioblasoma multiforme growth
...al vector that had been genetically manipulated to selectively express hsFlt3L to find out if it would increase the number of dendritic cells in the brain of laboratory rats with GBM. To evaluate whether hsFlt3L could shrink brain tumors and prolong survival, rats with GBM were injected with increasing ...Stanford study reveals that cells linked to asthma and eczema also help cure deadly illness in mice
...rmally to endothelin-1. The researchers could then selectively transplant these mast cells to mice that lacked the cells and thus see how it affected the ability to respond to endothelin-1 or bacterial infection. Most of the mice without mast cells died as a result of bacterial infection. But survival during sep...Leading tobacco manufacturer conceals links to tobacco research facility
...ch conducted in that facility appears to have been selectively reported in order to favourably shape public impressions about the safety of passive smoking." Dr Horton adds: "As the UK government launches its white paper on public health, ministers must be alert to the fact that parts of the tobacco industry hav...A key to pregnancy-associated malaria
...another member of this protein family, VAR2CSA, is selectively produced on the surface of infected cells that can bind to the placenta. They find that women, but not men, from endemic areas have circulating antibodies that recognize this protein, and that women with high levels of VAR2CSA-specific antibody give...New way of controlling cholesterol may help treat Alzheimer's
...tions, secretase inhibitors have to be tailored to selectively stop amyloid-beta production. Since they do not affect secretases, ACAT inhibitors may have fewer side effects." Kovacs is an assistant professor of Neurology at Harvard Medical School. ...MRI shows brain changes underlying language deficits in autism
... neuroimaging tests -- then we may be able to more selectively and effectively treat people with debilitating neurodevelopmental disorders like autism and SLI."...$5 million grant awarded to U.VA health system targets leukemia drug development, creates new jobs
...roteins that arise in leukemia patients. If we can selectively inhibit these proteins, we hope that leukemia can be shut down. Since the molecules are selective, the side effects of treatment and the long-term prognosis for leukemia patients should be significantly better than they are today." Bushweller a...