Timing appears essential to combining antiangiogenesis and radiation therapy
...e MGH Department of Radiation Therapy, the study's senior author. "The vessels are leaky, dilated, disfigured, and do not evenly inflitrate the tumor, which can interfere with standard cancer therapies. Chemotherapy drugs are not distributed throughout the tumor, and the oxygen level is low, making tumors ...Scientists identify protein critical to melanoma growth
...he Melanoma Program at Dana-Farber and the paper's senior author, showed that adding a chemical that quashed the activity of CDK2, the gene that manufactures CDK2 protein, dramatically slowed the growth and proliferation of the cancer cells. Unlike conventional chemotherapy drugs, a CDK2 inhibitor drug woul...Size of myocardial infarct measured using MRI
...as done are highly subjective and arbitrary," said senior study author and cardiologist Joo Lima, M.D., associate professor of medicine and radiology at The Johns Hopkins University School of Medicine and its Heart Institute. "Indeed, a person who has suffered damage to more than 30 percent of the left ven...Guidelines for following pediatric cancer survivors aim to reduce medical complications
...e After Completion of Therapy (ACT) clinic. She is senior author of the JCO report. Hudson co-chaired the seven-member task force that established the guidelines with Wendy Landier, R.N., C.P.N.P. (City of Hope Comprehensive Cancer Center, Duarte, Calif.). The task force was supported by a national panel of...Researchers report early success using saliva to detect oral cancer
...rnia at Los Angeles (UCLA) School of Dentistry and senior author on the paper, it may be possible with further refinement of the test, possibly by including additional cancer-linked mRNAs, to attain the necessary 99 to 100 percent accuracy of commercial diagnostic tests for oral squamous cell carcinoma, the...International gathering at UH examines top computer code
...INFN, who work with Alfredo Ferrari, who also is a senior physicist at CERN. The present version of FLUKA is the product of this team of authors. Following the course held at UH, FLUKA's source code will be available for the first time to scientists under a special license agreement between CERN and INF...Fair decisions more important when hospitals face crisis like SARS
...ls and minutes of meetings) and 35 interviews with senior administrators, physicians, managers, nurses, other staff, a patient and family members. The study found there were two distinct phases of priority setting at the hospital during the SARS outbreak, the initial containment phase and the subsequent...Few Americans are aware they have chronic kidney disease
... the rate a snap," said Thomas H. Hostetter, M.D., senior author of the study and director of NIDDK's National Kidney Disease Education Program (NKDEP). "The earlier we identify kidney disease the sooner we can treat it," said Hostetter. NKDEP is asking labs to streamline the process for identifying kidney ...Prentiss Foundation awards $5 million to University Hospitals
... deserving programs," adds Sherri L. Bishop, Esq., senior vice president for Institutional Relations and Development, University Hospitals Health System....Few Americans aware they have chronic kidney disease
...t's found this way." said Thomas H. Hostetter, MD, senior study author and director of NIDDK's National Kidney Disease Education Program (NKDEP). NKDEP recommends that doctors take creatinine a simple step further to estimate glomerular filtration rate (GFR). GFR is a more accurate gauge of how well the kid...McGill researchers identify new way to reduce cholesterol levels
...ffect blood cholesterol levels on their own," said senior author McGill Professor of dietetics and nutrition, Peter Jones. "Our research is the first to look at the complementary combined effects of these therapies." Seventy-four non-active individuals between the ages of 40 and 70 were recruited for the st...NHLBI statement on oral contraceptive study
...The data in the abstract have now been reviewed by senior statisticians at the WHI Clinical Coordinating Center. They repeated the analysis for OC and CVD in the WHI baseline data. They controlled for age and other factors and could not find a relationship between OC use and cardiovascular disease. The st...New study shows how mad cow prions hitch a ride into intestine
... carrying the infection. According to the study's senior author Neena Singh, M.D., Ph.D., associate professor of pathology, little is known about the mechanism by which prions cross the human intestinal barrier, which can be a particularly difficult obstacle to cross. "The mad cow epidemic is far from ove...To help your mind, take steps to help your heart, study says
... A recent study led by the new paper's senior author, Eric Larson, M.D., MPH, of the Group Health Cooperative, notes that people who have a certain genetic characteristic that puts them at higher risk for both heart disease and dementia may get more cognitive benefit than others from statin ther...Success of experimental herpes vaccine builds momentum for human clinical trials
...their mothers. Lead author Stephen E. Straus, MD, senior investigator in the Medical Virology Section in the Laboratory of Clinical Infectious Diseases at the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, tested the vaccines in two established animal models of ...Broad-based vaccination of wild mice could help reduce lyme disease risk in humans
...ine with the University of California, Irvine, and senior author on the paper. "When the vaccine is targeted to humans, only those who experienced a satisfactory immune response to the vaccine are protected; however, when the vaccine is targeted to wildlife carriers, the risk of infection is lowered for eve...Fred Hutchinson receives $9.7 million to lead early detection consortium
...s. ISB founding member Ruedi Aebersold, Ph.D., and senior research scientist Julian Watts, Ph.D., will oversee this effort.Pacific Northwest National Laboratory Richland, Wash. Researchers at PNNL, a world leader in the development of protein-separation technologies, will contribute a large suite ...Stanford study questions accuracy of ads for body scans
...y," said the study's lead author, Judy Illes, PhD, senior researcher in the school's Center for Biomedical E...s; and Scott Atlas, MD, professor of radiology and senior fellow, by courtesy, at the Hoover Institution....Molecular test predicts risk of breast cancer recurrence and who will benefit from chemotherapy
...ed with chemotherapy," said JoAnne Zujewski, M.D., senior investigator in NCI's Cancer Therapy Evaluation Program....Brain can be trained to process sound in alternate way, study shows
... postdoctoral research fellow in the laboratory of senior author Michael M. Merzenich, PhD, co-director of the Coleman Memorial Laboratory in the UCSF Keck Center for Integrative Neuroscience and UCSF professor of otolaryngology. The study was published recently in Proceedings of the National Academy of Sci...