New molecular classification of breast cancer predicts response to chemotherapy
...elect the optimal treatment for patients, says the senior investigator, Lajos Pusztai, M.D., Ph.D., an associate professor in the Department of Breast Medical Oncology. Four major molecular subgroups of breast cancer ? normal-like, luminal (ER-positive), basal-like (mostly ER-negative), or erbb2+ (mostly HE...Multi-center study finds therapy boosts kidney transplants in 'highly sensitized' patients
... the study's principal investigator, the article's senior author and a professor of pediatrics at the University of California, Los Angeles. "The good thing about IVIG is that it modulates the immune system, it doesn't suppress it. It appears to 'turn off' deleterious immune responses without damaging the i...Physicians may need to dig deeper when treating HIV-related lymphomas
...bably differ for these sub-types of disease," says senior author Alexandra M. Levine, M.D., Distinguished Professor of Medicine, chief of hematology at the Keck School of Medicine of USC and medical director of the USC/Norris Cancer Hospital. The USC hematologists reviewed records of more than 350 patients ...Lab study: Protein delivered via genetically engineered virus slowed glioblasoma multiforme growth
...h Institute at Cedars-Sinai Medical Center and the senior author of the study. "Since gene therapy has given us the tool to deliver this protein, our hope is to translate these laboratory studies into clinical trials in patients with GBM." GBM tumors develop in the supportive tissue of the brain and gr...Diabetics with mental disorders at increased risk for diabetic complications
...the Regenstrief Institute, Inc. Dr. Carney is the senior author of the study which looked at insurance claims data from more than 26,000 diabetic adults between the ages of 18 and 64 living in Iowa. "Even when we controlled for utilization of healthcare services, diabetics with mental disorders did less w...SIDS risk linked to lack of experience with tummy-sleeping
...ve a 19-fold increased risk of sudden death," says senior author Bradley T. Thach, M.D., a Washington University pediatrician at St. Louis Children's Hospital. "We wondered if these babies, finding themselves face down, fail to turn their heads to breathe easier. If so, is that because their reflexes haven'...Nursing homes register 41 percent drop in residents' pain
...try, a project manager, and Sara Banks Freilich, a senior health information analyst, at Quality Partners. Therese Rochon, a nurse study coordinator, and Debra DeSilva, a former project coordinator, at Brown's Center for Gerontology and Health Care Research also worked on the project. ...Two-fisted assault on dopamine transport system may be foundation of Parkinson's disease
... UB School of Medicine and Biomedical Sciences and senior author. "Based on these findings, we have identified several ways to stabilize microtubules against the onslaught of rotenone. These results ultimately may lead to novel therapies for Parkinson's disease." Results of the resea...Impact of 2002 Canadian forest fires felt 700 miles away in Baltimore, Maryland
...t of Environmental Health Sciences and the study's senior author. The researchers used satellite images, trajectory models, light detection and ranging measurements to track emissions from the Canadian forest fires to levels of particulate matter in Baltimore. During the peak of the episodes, ambient PM 2.5...2004 Science-in-Society Award winners announced
... Woodbury (chair), Health magazine; Steve Tally, senior science and technology writer at Purdue University; and Debra Sherman of Reuters . Magazine entries were evaluated by Adam Rogers (chair), Wired magazine; Kyla Dunn, NOVA; and Keith Haglund, Science News . The Science-in-Society awards are admini...VGTI researchers help uncover why aging reduces immune system function
...k was led by Janko Nikolich-Zugich, M.D., Ph.D., a senior scientist at the VGTI. The scientists hope this ne...mmunology in the OHSU School of Medicine, and is a senior scientist at the OHSU Oregon National Primate Research Center. "Throughout our lives, we have a very...Drinking water could be beneficial to patients with low blood pressure
...ial College London and St Mary's Hospital, and the senior author of the research, comments: "This surprising discovery that water can have such an effect on blood pressure could help us to treat both sufferers of autonomic failure, and many people who suffer from low blood pressure generally, especially tho...Employment reduces chronic drug use, UH professors find
...ton "think tank" Affiliated Systems, where he is a senior research scientist. Assisted by Victoria L. Brown, an adjunct assistant professor at the UH College of Pharmacy and research scientist with Affiliated Systems, and Micah A. Riley, a research assistant with Affiliated Systems, Montoya found that welf...Herpes virus offers new hope in curing cancer
...esearch Trials Office at Cincinnati Children's and senior author of the new study. "It was surprising that with only one injection, we could make a large tumor disappear. We were able to cure a majority of the mice with neuroblastoma with a single injection of the virus," Dr. Cripe said. While the herpes si...Using celebrities to market drugs and diseases: whats the problem?
...se." Moynihan cites an industry report in which a senior marketing executive says that "a partnership between a celebrity and a brand has an intangible sort of magic." The executive shares her tips on maximizing the magic: "use an A-list celebrity," find a "news-hook" to link the celebrity to your product...Testosterone deficiency found in one-third of diabetic men
...ns of type 2 diabetes," said Paresh Dandona, M.D., senior author on the study and director of the Division of Endocrinology, Diabetes and Metabolism at the University at Buffalo and Kaleida Health, where the study was conducted. Results of the study appear in the November issue of ...New research shows stomach (gastric) cancer originates from bone marrow derived stem cells
... University College of Physicians and Surgeons and senior author of the study. "The implications of this study may lead to new methods of diagnosis and treatment of many cancers particularly those that have been linked to chronic inflammation such as stomach, esophagus, lung, pancreas, liver, etc." A comm...University of Utah study suggests cellular waste to blame for a form of blinding eye disease
... according to Kang Zhang, M.D., Ph.D., the study's senior author. This process of converting light to electrical signals in the retina requires a tremendous amount of energy which, in turn, creates waste in the form of carbon dioxide and bicarbonate. According to the paper, patients in the stud...Study highlights importance of pesticide worker dermal exposure
...t of Environmental Health Sciences and the study's senior author.......poses," says lead investigator Dr. Brian Levine, a senior scientist with The Rotman Research Institute at Baycrest and associate professor in Psychology and Neurology, University of Toronto. "Factual autobiographical memory grounds us in time and gives continuity to our lives. Episodic autobiographical memo...