Stanford researcher to find cure for widespread Celiac disease
...ance) is an hereditary disorder characterized by a sensitivity to the toxic effects of gluten in the diet, leading to abnormal small-intestinal structure, malabsorption, and intolerance to gluten, a component of nutritionally important proteins found in common dietary food grains such as wheat, rye and barley. ...New test predicts pregnancy problems long before they happen
...ter. It's more accurate as time goes on, with the sensitivity the ability to correctly identify those who will ... the first test that provides such high degrees of sensitivity and specificity at such a low gestational age," says Hermida.Blood pressure varies in predictable wa...Non-traditional tests may be dynamic duo in predicting heart problems
...iate risk may benefit from profiling based on high sensitivity CRP levels and coronary calcium, as both factors contribute independently toward the incidence of cardiovascular events," says Detrano. However, he adds that the findings are not strong enough to back widespread screening. The research didn't addr...Blocking enzyme found to ease anxiety without causing sedation
...knocking out PKC epsilon increases GABA-A receptor sensitivity to neurosteroids, and thereby decreases anxiety. "PKC modulates the modulator," Messing said. Because it is an intermediary, it is a promising focus for drugs that could decouple the biochemical pathway that leads to anxiety from the pathway that lea...Fred Hutchinson oversees two grants of nearly $8 million to develop blood test for breast cancer
...arkers are mutually complementary and best improve sensitivity when used together. Another key to the success of such a screening tool is the ability to interpret the results in a statistically meaningful way, taking into account the woman's own personal biomarker behavior, including how these levels may natural...American Thoracic Society journal news tips for October (first issue)
... of both sexes to tussive agents showed that cough sensitivity was greater in females than males at a clinic for ...n compared with men have a heightened cough reflex sensitivity to both capsaicin and citric acid cough challenges. A similar differencebetween the sexes was also ...Predicting who is most likely to quit smoking
...treatment regime. Healthcare providers need great sensitivity when discussing smoking with a patient and to understand the reason they smoke. For instance, if the patient smokes because they are stressed, the cause of the stress should be tackled. Many patients believe that once they have been diagnosed with c...Mild injury may render brain cells vulnerable to immune system attack
...ve excitation mediated by glutamate and a neuron's sensitivity to attack by complement." In their experiments reported in Neuron, Xiong and McNamara exposed cultures of neurons and astrocytes, first to modest levels of glutamate, as might be generated by a mild insult to the brain. When they next exposed these s...Researchers discover 'doorways' into brain cells
...smitters and drugs -- thereby controlling neuronal sensitivity to such external chemical triggers. The newly disc...tegies for treating drug addiction and maintaining sensitivity of patients to therapeutic drugs. "It seems quite reasonable to imagine developing techniques to con...Visceral fat loss after dieting is not necessarily responsible for disease risk improvements
... al. Effects of weight loss on changes in insulin sensitivity and lipid concentrations in premenopausal African American and white women. Am J Clin Nutr 2002:76:923-7....New centers to research, reduce asthma disparities
...n asthma disparities, such as ethnic variations in sensitivity to environmental allergens and the interrelationship between genetic susceptibility and stress, smoking, and exposure to diesel exhaust in provoking asthma symptoms. The Centers will also collaborate on training activities -- a critical feature of ...Why are people who recover from major depression never really out of the woods?
...re. Related research has shown that this emotional sensitivity may be a risk factor for depression recurrence. "This phenomenon is seen in recovered patients -- whether they're on maintenance medication or not, there remains a persistent vulnerability for further episodes. Now we've found a clue using brain imag...Jefferson scientists find evidence of greater sensitivity to addictive drugs in adolescence
...ll be looking to see if this increase is a clue to sensitivity to addiction and sensitivity to such drugs as therapeutic agents," says Dr. Ehrlich. "Many molecules have been implicated in bot...Chronic stress can interfere with normal function of the immune system
... also were found to have diminished glucocorticoid sensitivity compared to parents of medically healthy children. This hormone is responsible for turning off the in vitro production of the pro-inflammatory cytokines interleukin-1B, interleukin-6 and tumor necrosis factor, said Dr. Miller. The good news found by ...New data examines effect of inhaled corticosteroids (ICS) on survival in patients with COPD
... risk of death (HR 0.34, 95% CI: 0.21, 0.56). In a sensitivity analysis including only those COPD patients without a history of asthma (n=840), the reduction in risk of death associated with the use of ICS plus salmeterol remained significant (HR 0.35, 95% CI: 0.17, 0.71). Use of inhaled corticosteroids was asso...Coffee addicts at reduced risk of type 2 diabetes?
...s issue of THE LANCET. Caffeine is known to reduce sensitivity to insulin (responsible for the metabolism of glucose), although other components of coffee such as magnesium and chlorogenic acid could offer some health benefits. Rob van Dam and colleagues from the Dutch national Institute for Public Health and th...Comparing screening instruments for alcohol dependence and abuse
...d from other screens, that is designed to maximize sensitivity while maintaining good specificity. The RAPS4, a ...he calls this "a wonderful opportunity to test the sensitivity and specificity of the instrument from a cross-cultural perspective, [with] implications for its use...Nation's two largest medical specialty groups issue migraine treatment guidelines
...d pain, symptoms can include nausea, vomiting, and sensitivity to light, noise and odors. The first line NSAIDs proven to work are the familiar, inexpensive, over-the-counter, medications aspirin and ibuprofen as well as naproxen sodium and a combination of acetaminophen plus aspirin and caffeine. Acetaminophen ...Other highlights in the November 20 issue of JNCI
...n Current screening tools for ovarian cancer lack sensitivity and specificity. One potential approach to screening for the disease may be to detect allelic imbalance, the loss or gain of chromosomal regions, in tumor DNA released into the blood after tumor cells die. In the November 20 issue of the Journal of ...$15 million grant spurs cancer collaboration; M. D. Anderson, University of Puerto Rico
... in Hispanic populations, we will increase our own sensitivity to minority needs," continues Gibbs. "It is our hope that this collaboration not only will improve our level of patient care, but will be the beginning of many long-term partnerships with cancer centers across the nation and the world." The NCI and...