Protein that helps skin cancer spread identified by Stanford researchers
... benign tumor into a killer. "When we blocked this sequence we also blocked the cancer from spreading," said K...Palo Alto Health Care System. The group found this sequence by studying skin samples from 12 children with RDEB. They used laboratory tools to activate molecula...Mechanism of RNA recoding: New twists in brain protein production
... new type of genetic code, which incorporates both sequence and structural signals." She anticipates this work, also funded in part by the National Institutes of Health, will "greatly increase our ability to interpret the information encoded in the genome." Researchers still don't know why editing occurs, bu...New hand-held information system for emergency responders
... and WISER organizes the critical information in a sequence most relevant to a first responder on-the-scene, a Hazmat specialist, or an emergency medical specialist (EMS). "First responders in general, and Hazmat units in particular, must make decisions quickly in handling hazardous-materials incidents," says...HIV-1 spread through six transmission lines in the UK
...ry of the HIV-1 subtype B strain from sampled gene sequence data. Molecular data on HIV-1 has become increasingly available since the introduction of routine HIV-1 gene sequencing for drug resistance. Scientists used this data to follow the changing number of infected individuals through time and estimate the...News tips from the 2005, 54th Annual Scientific Sessions of the American College of Cardiology
...justed the device's pacing program and lowered MRI sequence energy levels to see if the scan affected the settings or caused any other kind of problem, such as heating of the electrical leads and surrounding tissue. All patients and devices were closely monitored during the scans, some of which lasted up to ...Researchers close in on breast cancer vaccine
...structed a vaccine consisting of copies of the DNA sequence that makes mammaglobin-A in humans. The researchers theorized the DNA vaccine would rev up special immune cells called T cells to recognize mammaglobin-A as a foreign molecule when it is displayed on the surface of cells as an antigen (a small protei...Scientists replicate hepatitis C virus in laboratory
...es that have enzymatic function and can cleave RNA sequence at specific locations. These two ribozymes were designed to generate the correct ends of the HCV genome and to act as start and stop buttons to gene activity. The construct was "naked," meaning that it contained only nucleic acids, the genetic mate...Prestigious 2004 AAAS Philip Hauge Abelson Prize honors Maxine Singer
...rs, Singer has focused in particular on the LINE-1 sequence that is repeated thousands of times in human DNA, concluding that LINE-1 is a jumping gene capable of insertion to new places on chromosomal DNA. Elsewhere, scientists later found that LINE-1 insertions into a gene related to blood clotting are assoc...Effects of autism reach beyond language, new research suggests
...e students were then asked to write down the exact sequence they had just heard. The other tests evaluated how well the participants could solve specific problems. In one test, students were given a list of three words and asked to think of one word that, when combined with each of the three given words, woul...Pathogen-mimicking vaccine as strategy for cancer therapy
...vestigation. The paper shows that the CpG 7909 DNA sequence is safe, and increases the immune system's ability to recognize and destroy cancer cells. The Phase I study was conducted by the Lausanne Branch of the Ludwig Institute for Cancer Research (LICR) at the Lausanne University Hospital in Switzerland, in...Viral DNA sequence a possible trigger for breast cancer
A small sequence of DNA in the envelope (Env) protein of a mouse br...ly unrecognized trigger for breast cancer. The DNA sequence in question is usually found in immune cells and helps trigger the activation and proliferation of t...Newly discovered virus linked to childhood lung disorders and Kawasaki disease
...mately, two specimens were identified in which the sequence of chemical building blocks of the gene differed from that of known human coronaviruses. The Yale investigators, terming the novel virus indicated by their findings the New Haven coronavirus, then used probes specific for the virus to screen respirat...Entrepreneurism Center at UC San Diego funds commercialization of lung, shock, other devices
...uman Disease" $5,000 With the explosion of genomic sequence data and the completion of the human genome project, much of the progress in understanding the genetic basis of disease relies on computational analysis of the genomic data, including data on the variation in genes associated with a disease for a pop...ESA presents space solutions at post-Kyoto climate summit
...e, and how to adapt. This event is the latest in a sequence of annual gatherings, known as the Tenth Session of the Conference of the Parties to the United Nations Framework Convention on Climate Change (UNFCCC COP 10). With Kyoto on the verge of becoming effective, countries that have ratified the Protocol ...First US SARS vaccine trial opens at NIH
...llaboration of researchers had decoded the genetic sequence of the SARS coronavirus, opening many avenues of research to develop diagnostic tests, therapies and vaccines. An NIAID team, lead by NIAID Vaccine Research Center Director Gary J. Nabel, M.D., used the available SARS coronavirus genomic information ...Innovative take-off system could lead to safer, cleaner air travel
...e-art computer models, on the most efficient, safe sequence in which aircraft can take-off. Currently, runway controllers carry out their demanding job using their own observations and mental calculations, with limited reliance on technical aids. The system is being designed to take factors such as aircraft s...New research tool aids study of national well-being
...sked 909 women to recall the previous workday as a sequence of episodes and rate the psychological and social aspects of those activities. Results were compared to experiments based on more common "experience sampling" methods (ESM) used in well-being studies, in which subjects record their actions and feelin...Methylphenidate improves attention, behavior of children surviving leukemia, brain tumors
...or a three-week course of treatment with MPH. Each sequence included a low dose of MPH (0.3 mg/kg of body weight), a moderate dose of MPH (0.6 mg/kg of body weight) and a placebo in one of the sequences (e.g., low dose, placebo, high dose). The drug and placebo were administered at school. The ef...Brains of people with autism recall letters of the alphabet in brain areas dealing with shapes
.... Specifically, the study volunteers were shown a sequence of letters. After each letter, they were asked to name the letter that preceded it. In some cases, they were asked to name the letter that appeared two letters previously. The autism volunteers' brain activation patterns were compared to a control......an influenza viruses. NIAID will rapidly make this sequence information publicly available through GenBank, an...rce Center, a Web-accessible collection of genetic sequence information accompanied by data analysis tools. "Influenza viruses present formidable scientific a...