Jefferson scientists use gene therapy to restore function of damaged heart cells in laboratory
... protein, which glows green. The latter provided a signal to the scientists that the inhibitor was indeed present in the heart cells. They then were able to use a video camera to actually measure how strong the individual heart cells were beating. "We put the ARKct into the cells, and failing human hearts...Women treated more aggressively for hypertension, yet results similar to men
... or not the symptoms are due to unstable angina or signal a real heart attack. "Hypertension afflicts more than one billion worldwide and has been proven to be an independent risk factor for death or further cardiac events after ACS," Newby explained. "There is little doubt that hypertensive women with ACS ...UCLA researchers to test experimental pill
...e a satellite dish. If you're a blood vessel, this signal tells you to grow. What we hope PTK/ZK does is block the receptor from working, sort of like snipping the wires in the satellite dish. We're hoping this drug keeps the cancer from growing, makes it more sensitive to the chemotherapy we're giving and ...Hearing aid research gets federal boost
... to improve the technology of acoustic sensing and signal processing so that we can minimize the influence o...phones, novel optical electronic sensors and novel signal processing. As principal investigator for the project, Miles will partner with researcher Douglas Jo...A little electrical boost may help many heart failure patients
...beat has already started, then sends an electrical signal to strengthen the heart's contraction. Last year, the U.S. Food and Drug Administration approved devices that deliver a different form of heart failure treatment called "cardiac resychronization therapy," or CRT, for treating a subgroup of patients w...Simple tests could signal and prevent heart disease in women, says Pittsburgh researcher
...a woman's condition through a few simple tests can signal when action should be taken to stop the cascade of events that could otherwise lead to heart attack. Insulin resistance can be measured by testing blood levels of insulin, glucose and adiponectin a type of fat-storing cell. Lipoprotein particles can...Brain signals from the paralyzed or injured captured by computer
...ovide rapid multidimensional control of a movement signal with precision and speed comparable to that achieved in monkeys by invasive BCIs. This remarkable control by a non-invasive BCI depends on an adaptive training algorithm that identifies and focuses on the particular EEG features that the person is be...Vital sign device improves resuscitation monitoring
...y adjust the transmission power so that a stronger signal is sent out and has a greater chance of being rece...r patients' data, thus giving a critical patient's signal an even greater chance of going through."This is the first wireless network designed to give priorit...Scientists map maturation of the human brain
...ested on standard measures of inhibition (the stop signal and Stroop tasks). They also completed mood and behavior ratings, and had their vital signs monitored during the study. The findings raise other questions such as whether nicotinic drugs could be used as treatments for ADHD, whether the effects we fo...Exercise has a more powerful impact on the brain than previously thought
...training resulted primarily from an enhanced brain signal to muscle," says Yue. The study's findings may change current methods of rehabilitation therapy for patients of all ages who are able to perform only low- to moderate-intensity exercise after an illness or injury. "It's well known that people recuper...Newborn screening is cost-effective in detecting rare but treatable genetic disease
...in fatty acids, amino acids or other chemicals may signal a genetic defect in how the body processes food. TMS can screen for more than 30 metabolic diseases. Many of thesediseases are rare, but collectively they affect one in 4,000 newborns, approximately the same percentage affected by Down syndrome. Rout...Brain maps perceptions, not reality
...y. The team then used a technique called intrinsic signal optical imaging to study the reaction to the same ...usion in the brains of squirrel monkeys. Intrinsic signal optical imaging uses a specially designed video camera to detect changes in light reflectance viewed...Radically new anti-rejection drug shown to offer safe control of immune system in Stanford study
...ls. The activation of these cells occurs through a signal from an enzyme called janus kinase 3, or JAK3. Knowing that a lack of JAK3 caused the same symptoms as seen in X-SCID patients, the Pfizer team screened thousands of compounds to look for inhibitors of that enzyme. They identified a promising molecul...New drug for non-small cell lung cancer shows efficacy
...gnals tumor cells to proliferate and grow.When the signal is disrupted, the tumors regress and apoptosis or celldeath occurs. A double-blind, randomized phase II clinical trial of gefinitib wasconducted at thirty academic and community oncology centers in theUnited States. Participating were 221 patients w......nhibitors (FTI), tyrosine kinase inhibitors (TKI), signal transduction inhibitors (STI), and EGF receptor in...ly will be a combination of chemotherapy and other signal transduction inhibitors," says Gilbert. "We need to block more than one pathway in a tumor that uses......tors that is regulated by the brain. An initiating signal from the brain instructs the pituitary gland to produce more luteinising hormone (LH). A feedback mechanism from the ovaries to the brain ensures that ovulation only occurs when the follicles and oocytes are mature. Matured follicles produce large qu...Rejection really hurts, UCLA psychologists find
...e're being excluded. This automatic alarm may be a signal for us to reestablish social bonds before harm befalls us." "These findings show how deeply rooted our need is for social connection," Eisenberger said. "There's something about exclusion from others that is perceived as being as harmful to our survi...NYU School of Medicine attracts a powerful MRI machine
...rlap. Physicists have also figured how to mask the signal from water, allowing the signals of other compound...rum at higher field strengths. "The massive proton signal from water, which makes up approximately 70% of our bodies, swamps all the other signals that you wa...Dating, delinquent friends key reasons why early puberty linked to delinquency in girls
...changes in appearance that result from puberty may signal to the girls themselves and others that they are ready for adult-like roles. "When adolescents enter puberty, they are looking for more adult roles and it may be that dating and finding friends who are involved in delinquency are ways they can satisf...Nanoneurosurgery, search for E-T life, bioscan technology and home holograms at frontiers of optics
...ed, and the device's response to the single photon signal is recorded and sent back to the lab. Because the researchers know the state of the second photon by looking at the first, they can determine the response of the remote optical device to a well-known signal. As a result, they know how to interpret ...