Insulin Resistance And Obesity Avoided In Genetically Modified Mice, As Reported In Science
...odel, but it has the possibility of being a really significant drug if itworks," said Brian Kennedy of the Merck Frosst Center for Therapeutic Researchin Pointe Claire-Dorval, Quebec, Canada, who was a member of the research team. In 1995, there were 35 million cases of type II diabetes, or"non-insulin-...Heart Valve Abnormalities Examined In Relation To Duration Of Diet Drug Use
...Among other conclusions, the researchers found: no significant difference in the incidence of aortic valveregurgi... compared tothe control group; no significant difference in the prevalence of regurgitationin the mitral valve between the two groups. Mitral valv...T-Cell Memory Finding May Provide Key To Cancer, AIDS Vaccines
...gen for at least five celldivisions -- to create a significant number of memory T cells. Without strongstimulation for three to four days, few memory cells emerged. By finding theanswer to this fairly basic scientific question, "we have stumbled into theworld of clinical relevance," jokes Ashton-Rickardt. "No va...NIA Launches National Study To Treat Mild Cognitive Impairment
...itive testing may reveal people with MCI to have a significant memoryproblem, their other cognitive functions remain normal and are for the most partunaffected by MCI," said Dr. Thal. "Prior to today, most treatments tested forslowing memory decline have been evaluated in patients with well-defined AD. What we ...Study Of Women And Hearing Reveals Need For Routine Hearing Tests
...said. "Ourresults underscore the likelihood that a significant proportion of older womenhave undiagnosed and untreated hearing loss," Erler added. "They clearly suggestthat both aging populations and their health care providers need to developgreater awareness of hearing loss and the need for routine testing." G...Higher Doses Of Methadone May Do The Trick, New Study Says
...100mg. Meanwhile, he adds, "our results show that significant improvement occurswith daily doses of80 mg or greater, though the 40 to 50 mg minimum dose still benefits thepublic's health." The study was supported by U.S. Public Health Service grants. Otherresearchers includeGeorge E. Bigelow, Ph.D., Ira ...Lo-Cal Diet Slows Prostate Cancer In Animals, New Research Finds
... orcarbohydrate -- had no significant influence on tumor size. All slowedtumor growth to a similar degree. The mouse experiment using transplanted human prostate-tumor cells also showed that a diet lower incalori...Office Stress, Large Family Responsibilities Put Women At Risk
...ite-collar women who have universitydegrees that a significant association was observed between blood pressure an...ination with the volume of housework they did hada significant effect on their blood pressure. The research was supported by grants from the National Health Resear...Debilitating Body Image Disorder Often Begins In Teens; Likely To Be Missed
... are not sufficient fordiagnosis unless they cause significant distress or impairment in functioning. "The problem is that adolescenceis when this usually begins and it's not being picked up... people see it and trivialize it," said Phillips."This is not just a phase." Larger studies on childr...Prevalence Of Sexual Abuse In Men
...xperiences as children and that this in turn was a significant predictor of a similar experience in adulthood. King et al comment that previous research has concentrated on the possibility of sexually abused boys becoming perpetrators in adulthood and that the possibility of early abuse leading to further victi...Hardening Of The Aorta Increases The Risk Of Stroke
...erosis inthe ascending aorta is an independent and significant risk factor." Most stroke-causing blood clots form in the heart or in the carotidarteries leading to the brain, but the source of about 40 percent of strokes isunknown. Davila-Roman and Barzilai believe that diseased aortas could explainsome ......ing research sessions will offer reports of highly significant and timely findings that have occurred within the last few months. A new feature at the Annual Meeting is a special lecture, given this year by Nobel Laureate James D. Watson, Ph.D., entitled "From the Double Helix to DNA Tumor Viruses." "As the pace...Disabilities Don't Raise Insurance Costs
...accommodations to make for thoseemployees. Other significant results: In general, large and medium-sized organizations providedaccommodations for employees with disabilities more often than smallerorganizations did. Few companies overall -- less than 29 percent -- offered suchstaples as modified training an...Inhibiting Growth Of New Blood Vessels Reduces Heart Disease Plaque In Mice
...were about the same. However, there was a significant difference in plaque accumulationbetween the treat... were32 weeks of age, they found smaller but still significant differences in plaquegrowth between the treated and untreated groups. Finally, mice treated...Patients May Not Be Receiving The Highest Quality Of Care
... to managed carepatients, but we also found that a significant number of all physicians did notfollow nationally accepted guidelines for care, regardless of the incentives." Based on their results, the researchers believe the medical community needsbetter quality control measures to ensure that physicians provid...New Research Points The Way To Restoring Noise-Induced Hearing Loss In Mammals, Including Humans
...nimal. "Our results bring us one small but significant step closer to achievinghair-cell regeneration in humans," said Rubel. "It remains to be determined whether release from such inhibition notonly will cause cell proliferation in the organ of Corti, but also initiatefurther steps required for ...Rice, Medical Center Institutions Join Forces On Health Initiative
... develop publicpolicies that could contribute to a significant decrease in illness and increasein well-being and productivity. Rice and the University of Texas-Houston Health Science Center officialsannounced today the research team--to be led by Dr. Alvin R. Tarlov of HarvardUniversity--will be based at...IOM Report Offers New Look At U.S. Vaccine Priorities
... priority. However, the new report differs in two significant ways fromthe 1985 project. First, it includes vaccines not only for infectious diseases,but also therapeutic and preventive vaccines for chronic conditions such ascancer and autoimmune diseases. Second, it evaluates both short-term (10 years)and lo......paclitaxel or cisplatin withoutBNP7787 resulted in significant neurotoxicity in the treated subjects. Theoutcome...platin or paclitaxel populations werestatistically significant relative to the subjects that received eitherpaclitaxel or cisplatin without BNP7787. These laborato...Stress And Surgery May Increase Development Of Cancerous Tumors
...essedby physical stress or surgery, resulting in a significant increase in tumordevelopment. Thesefindings suggest that protective measures should be considered to preventmetastasis for patientsundergoing surgery to remove a cancerous tumor, according to Gayle Page,D.N.Sc., R.N.,associate professor and Independe...