Environmental enrichment lessens protein deficits in mouse model of Huntington's
...nder of a rotarod apparatus. The cylinder rotated, slowly at first, then accelerating. The amount of time a mouse remained on the rotating rod was a measure of Huntington's disease-associated motor symptoms. In transgenic mice housed without enrichment, BDNF protein levels declined, but in mice housed in en...Thursday, March 4, 2004 news tips
...D death rates actually increased or decreased more slowly in the 1990s, and the numbers of CHD deaths in those age groups went up annually by 3.2% and 1.6%, respectively. "Coronary heart disease deaths in the U.S. changed little in absolute numbers from 1980-2000 due to increases not only at ages 85+ but a...Research clarifies how Alzheimer's medicines may reduce interference with learning and memory
...linergic that crosses the blood-brain barrier more slowly and incompletely compared with scopolamine. As expected, in the experimental group, memory for word-pairs learned after scopolamine administration suffered significantly but memory for word-pairs learned immediately before injection was spared. Mo...Jan/Feb 2004 Annals of Family Medicine tip sheet
...d and ill-suited for older patients suffering from slowly progressive chronic illness, four researchers from the University of California Davis School of Medicine have proposed a new framework for palliative care the TLC model. The new model is named for its five defining characteristics timely, team-ori...National survey finds U.S. public enthusiastic about cancer screening
... be tested for "pseudodisease," cancers growing so slowly that they would never cause problems even if untreated. Moreover, the researchers report great interest in the total body computed tomographic (CT) screening, although no data support its benefit or safety, and it is not endorsed by any profession...Concord grape juice improved memory and neuro-motor skills in animal study
...alance on a horizontal stationary rod; a rotating, slowly accelerating rod; and various sized planks, and their ability to hold onto a suspended wire and an inclined wire screen. Some of those tests saw improvements in either or both of the group consuming a 10% solution of Concord grape juice and the grou...UF 'smart home' demonstrates concept of automated elderly help and care
...ho obtain and use the devices tend to decline more slowly than those who remain unassisted and they also cost the system less for care, he said. Contrary to the stereotype, the elderly often welcome technology. One elderly woman who received a computer told him, "'I used to wake up every morning and pray, ...OHSU researchers study recent monkeypox outbreak
...s ago. They found that T-cell immunity dropped off slowly over time, but antibody immunity could typically last for a lifetime. This indicates that the smallpox vaccine may provide protection that lasts far longer than the previously accepted 3 to 5 years. Fortunately, the smallpox vaccine not only protect...Scientists map maturation of the human brain
...nsory parts of the brain (the top-middle portion), slowly spreading downwards and forwards, over the entire brain surface," says Nitin Gogtay, MD. "The surprising thing is that the sequence in which the cortex matures appears to agree with regionally relevant milestones in cognitive development, and also re...Drug improves brain structure in Alzheimer's patients
...te increased and the hippocampus deteriorated more slowly than among the patients who received a placebo. The implication is that we may be able to do something to change the progression of this disease." The researchers believe the drug may have a protective effect on the brains of Alzheimer's patients bec...Aortic aneurysm death risk hinges on choice of surgeon, study finds
...largest blood vessel. They can stay intact or grow slowly for years, often without symptoms, before suddenly bursting open unpredictably. Or, a tear within the multi-layered wall of the aorta, called an aortic dissection, can grow and eventually lead to an aneurysm at the weakened spot. Patients whose aneur...The changing face of severe asthma
... be two distinct forms of the disease, one that is slowly progressive over time and another that is associated with significant loss of lung function very shortly after onset," said Dr. Spahn....Promising drug proves ineffective as treatment for hearing loss
...ive either Methotrexate or placebo. Prednisone was slowly tapered in both groups over a 3-month period while the Methotrexate and placebo doses were increased. The results showed that Methotrexate was no more effective than the placebo in maintaining the hearing gain achieved with Prednisone. Of the 67 pat...'Genetic switch' proves two mechanisms exist by which immune system cells differentiate
...ing T-cells peaks in a person's mid-teens and then slowly erodes. This is one reason why older people and babies are frequently sickened by or die from diseases that cause little harm to those from their teenage years to midlife. Likewise, certain diseases can kill off T-cells, making the body vulnerable t...Making tiny plastic particles to deliver lifesaving medicine
...lymers used in making such particles must dissolve slowly in the body, releasing the medicine over a prescribed period of hours, days or even weeks. Also, these materials must be strong and flexible, so that the particles do not crack or crumble before delivering their treatment. At the same time, the parti...US prostate cancer deaths down one third in men aged 5074: Europe following?
... cancer mortality rates, which had been increasing slowly during the 1970s and 1980s, suddenly started to fall rapidly during the 1990s. Between 1990 and 2000, US prostate cancer mortality fell by one third at ages 50-74, and it fell by one quarter at ages 75-84. Definite decreases are also beginning to be ...Uninsured face higher death risk from aorta problems
...argest blood vessel an AAA can stay intact or grow slowly for years, often without symptoms, before suddenly bursting open unpredictably. Or, a tear within the multi-layered wall of the aorta, called an aortic dissection, can grow and eventually lead to an aneurysm at the weakened spot. Patients whose aneur......d senescence the heart has a relatively stable but slowly diminishing number of myocytes [heart muscle cells...]Evidence challenging the accepted wisdom has been slowly accumulating," they wrote. Dr. Anversa's investigation of heart failure has produced mounting evid...On the horizon of glucose monitoring: A review
... from a site other than the finger appears to more slowly reflect the changes in blood sugar, meaning a sample from the finger might detect elevated blood glucose levels earlier than a sample from an alternate site," Gabbay said. "And although less painful than the nerve-rich fingertips, these products stil...Lens replacement material holds prospect of 'young' eyes for people over 40
... according to one theory, the lenses in their eyes slowly harden making it more and more difficult to focus on nearby objects. The current solution for most people is reading glasses or contacts. Even people who undergo corrective laser surgery often still need glasses for reading and up close focusing. "...