Other highlights in the September 3 issue of JNCI
...st longer, progress more rapidly, and regress more slowly in women infected with oncogenic types of human papillomavirus (HPV) compared with women infected with a non-oncogenic HPV type or in women with no HPV infection, according to a study by Nicolas F. Schlecht, Eduardo L. Franco, and colleagues at McGil...FDA approves Wellbutrin XL(TM)
...ave a two-layered coating designed to release drug slowly in the body. GlaxoSmithKline licensed this once-daily formulation of bupropion hydrochloride from Biovail Corporation in October 2001. Wellbutrin XL will be available in two strengths, 150 mg and 300 mg, to allow for dosing flexibility. The usual ta...New Alzheimer projections add urgency to search for prevention, cure
...lth planning. But because Alzheimer's can progress slowly and is often not diagnosed, and because there is no requirement that the disease be reported, it has been difficult to gauge the scope of the problem. According to Sheldon Goldberg, president and CEO of the Alzheimer's Association, "If left uncheck...Job stress may be missing link between workplace exercise and heart risk
...tes. They found that while arteries thickened more slowly in those who exercised more during their leisure time, arteries actually thickened faster among those who were very physically active during the workday. But when the researchers measured psychological stress related to work (asking how much sleep p...... said. However, diabetic ulcers or sores that heal slowly are another story. Over human history, thousands of preparations and treatments have been developed to assist in wound repair, he explained. Collagen itself has long been considered a favorite material for wound treatment because it is inexpensive, ...Contact lenses that dispense prescription drugs
...act lenses containing tiny embedded particles that slowly release drugs directly where they're needed. The r...rugs contained in a contact lens could be released slowly enough to stay in the eye. Chauhan and his graduate student and coauthor, Derya Gulsen, have found a...Laser technology helps measure pollution from NYC buses
.... Nitric oxide forms inside automobile engines and slowly reacts with oxygen to create nitrogen dioxide. NO2 itself is responsible for the brownish haze that hangs over many cities during the afternoon of sunny days. Formaldehyde also contributes to urban smog; methane is a powerful greenhouse gas; SO2 cont...Heart gone haywire blamed in some sudden infant deaths
...drome, the heart electrically recharges itself too slowly or in a disorganized fashion in preparation for the next heartbeat, says lead author Michael J. Ackerman, M.D., Ph.D., an assistant professor at the Mayo Clinic in Rochester, Minn. When combined with a trigger, such as intense emotion or physical exe...Aging lowers activity in brain's language areas; performance unaffected
..."We demonstrated that brain activity changes occur slowly with age and not as a sudden change occurring in latter decades," Gitelman said. In the study, 50 participants who were healthy, right-handed and had no evidence of a decline in thinking abilities performed a pronunciation task that involved readi...Memory training may help some Alzheimer's patients in the early stages of the disease
...t the rehabilitation strategy might have worked by slowly re-establishing links between phonological (name) and semantic (person-specific) representations in the parts of the brain's neocortex, surface areas that deal with language and problem-solving, and are less damaged early in AD than areas known to be...'Virtual stomach' reveals pill's path
... designed to remain in the stomach for hours while slowly releasing medicine. The researchers note that, although many medications are prepared in extended-release form, the details of exactly how the pills break down and release medicine in the stomach are largely unknown. The new "virtual stomach" has s...Recruitment of 50,000 sisters of women with breast cancer
.... Because most diseases like breast cancer develop slowly over a long period of time, researchers want to collect information from women who are healthy today and follow them over time to learn who stays healthy and who doesn't....UCLA seeks thousands of current and former smokers for landmark lung cancer screening trial
...y tumor size -- determine whether a cancer spreads slowly or rapidly. Finding a small cancer on CT or chest X-ray is not necessarily the same as finding an early lung cancer." And there's another wrinkle. Most of the lung abnormalities detected with low-dose CT are ultimately found to be non-cancerous, yet ...NIH supports ice slurry at Argonne
...cs would begin immediate cool down. The ice slurry slowly melts in the body and is removed with a suction device on the end of the endotracheal tube. Other goals remain for slurry, such as using it for stroke treatment, and there are many other questions researchers need to answer before continuing with te...New procedure kills liver tumors without surgery
...ssue." After the heating session, the needles are slowly withdrawn at a slightly lower temperature in order to cauterize the wound and minimize bleeding. All the patient needs is a small bandage on the skin and a half-day of rest before leaving the hospital. Side effects tend to be minimal but include pain...American Thoracic Society Journal news tips for August (second issue)
...he degree of their airflow restriction. COPD is a slowly progressive airway disease that produces a serious decrease in lung function. This loss is associated with an abnormal inflammatory response of the lungs tonoxious particles and gasses associated with long-term cigarette use. The characteristics of...Study adds to knowledge of what it takes to stand up, walk
...nts and blood samples were taken, the pressure was slowly increased in the chamber and additional readings and blood samples were recorded. "One-legged LBNP led to a rise in muscle sympathetic nerve activity, the amount of norepinephrine in the blood plasma, and the norepinephrine in the interstitium, or t...Immune system supressor drug found effective in treating precancerous blood disorder
...ndrome (MDS), a condition in which the bone marrow slowly stops making blood cells and platelets. One-third...e older adults, the bone marrow becomes defective, slowly ceasing production of healthy blood cells, instead making defective blood cells. About 14,000 new c...Mad hatters, seafood jubilees, & Pfiesteria Files
...xygen causes them to behave strangely as they move slowly and struggle for air, and it gives residents a chance to capture some of the victims. As many as several thousand pounds of fish and shellfish may be harvested at one time. By sunrise, the "jubilee" conditions subside and the affected fish swim bac...With cues from nature, scientists develop new method to purify drugs
... chromatography, involves letting the mixture flow slowly down a column. Different compounds descend at different speeds, so as a mixture drips down the column, its molecules separate into pure bands. The desired drug can then be captured as a purified band. The process requires considerable use of expensiv...