Duke Study Uses Tiny Temperature Changes To Probe Water-Exclusion At Protein Binding Sites
...emical reactions in the body typically unfold when smaller molecules,called "ligands" form temporary combinations, called complexes,with protein molecules at special protein binding sites. Pharmaceuticalresearchers can elicit biological effects by designing drugs to link upwith proteins just as natural ligan......y focusing on patients with isolated kidney tumors smaller than a tennis ball and no other hope. In the procedure, Lewin inserts a probe resembling a hypodermic needle into the patients abdomen. He guides the tip of the probe into the heart of the tumor using magnetic resonance imaging (MRI) techniqu...New Ultrasound Technique Is Alternative To Cerebral Angiography
...n a piece ofthis plaque breaks off and lodges in a smaller blood vessel, shutting off theflow of blood to that part of the brain. Stroke also can happen when the carotiditself is completely blocked. A person whose artery is 70 percent blocked or more has four times therisk of stroke as a person with ...Cancer Protection Compound Abundant In Broccoli Sprouts
...oped fewertumors, and thosethat did get tumors had smaller growths that took longer to develop. In a paper published in tomorrow's issue of the Proceedings of the NationalAcademy ofSciences, Talalay and his coworkers describe their successful efforts to buildon their 1992discovery of sulforaphane's chem...Study Demonstrates The Benefits Of Mammography In Women Under 50
...at were detected throughmammography were generally smaller and less appeared aggressive under themicroscope than those tumors that were detected through physical exams," Dr.Bradley said. Mammography can detect tumors in the breast which are too small to feel,Dr. Bradley said, which makes it an effect...NIH Honors Emory Researcher With Merit Award For Work On Renin-Angiotensin System
...t the male knockout mice fathered litters withmuch smaller numbers of offspring than those of typical wild mice, suggestingthat testis ACE is necessary for full male fertility (Laboratory Investigation,1994). In addition, mice lacking somatic ACE have an unusual renal phenotypecharacterized by the inability ...Natural Estrogens May Help Protect Women From Brain Damage During Stroke
... of cerebralblood flow duringstroke than males and smaller amounts of damaged brain tissue afterward. When strokes were created in female rats whose ovaries had been surgicallyremoved, and whotherefore had lower levels of natural estrogen, stroke damage was essentiallythe same as in males. This indicate...Survey Finds Increasing Popularity Of Acute Stroke Teams In U.S. Hospitals
... One finding of the survey, which should appeal to smaller hospitals, isthe cost, according to Alberts. ...cide to establish ASTs. "Officials at many smaller hospitals feel that these teams are staffedprimarily by residents and fellows, which are found prima...Study Finds Aspirin Does Not Prevent High-Risk Cases Of Preeclampsia
... wereactually at high risk. He added that several smaller trials found that lowdoses of aspirin could reduce...ave resulted in the risk of preeclampsia appearing smaller in the groupas a whole. Another possibility is "publication bias," which occurs becausestudies that...Radio Frequencies Used To Kill Inoperable Liver Tumors At Penn's Cancer Center
...erved advantageous over cryosurgery because a much smaller probe is used, which ultimately decreases vascular complications," Fraker concludes....Successful Cancer Therapy May Doom Later Treatments To Failure
... designingchemotherapy agents. They may need to be smaller and more agile. "The public,investors, and the gov...olid tumors often contained amixture of bigger and smaller openings. Pore size also varied depending on wherethe cells grew. Breast tumors grown in the brain, ...Clot-Busters As Effective As Surgery To Clear Blockages In Legs
.... "If we do need to operate, it's frequently amuch smaller operation, such as patching one small area.Thrombolysis lets surgeons be selective in whom they operate on,and converts an emergency procedure to an elective one." Not all physicians are as enthusiastic. In an accompanyingeditorial in the journa...Health Workers May Experience Costly Dislocation As Health Spending Growth Slows
...ment will also be strongly felt in areas where the smaller scale of non-health employment makes health services a dominant employer, such as West Virginia and North Dakota. In areas like the Mountain and Pacific regions, which have especially lean health services systems, it is possible and even likely that ...New Treatment Targets Most Malignant Brain Tumors
... radioactively labeledantibodies directly into the smaller tumors. Bigner and his colleagues also plan to improve the monoclonal antibody,creating versions that remain stable longer in the body, or are smallermolecules that might penetrate tumors better. However, the research team has already...Treatment Of Distal Ureteral Stones: ESWL Versus URS: A Prospective Randomized Study
...nts with distal ureteral stones. Forty had stones smaller than 5millimeters and 40 larger. Following urete...ween the twotechniques proved more significant for smaller stones. The investigators sawthe only drawbacks to URS use was stent placement in patients for 4 to......patients with more radiation, but dividing it into smaller doses. Instead ofhaving one treatment per day, all patients had two treatments per day for fiveto six weeks. At the same time, half of the 116 patients in the study alsoreceived cisplatin and 5-fluorouracil, two chemotherapy drugs commonly used totr...International Panel Evaluates Testing For Drug Resistance In HIV
...patientbut miss other resistant strains present in smaller amounts. Also, becauseprevious drug treatment may lead to the survival of resistant strains--even atundetectable levels--interpretation of any resistance assays should also takeinto account the patient's complete treatment history. Although an as...World's First Producer To Repair Brain Damage From Stroke
...njects these cells through an opening of the skull smaller than a pea. Afterinjection, the opening is closed with one stitch. The patient goes home the next morning. Follow-up assessments for safety and efficacy will be done at 1, 2, 4,8, 12, 16, 24, and 36 weeks. Beginning with the 12-month visit...Repairing Cranio-Facial Deformities From The Inside Out
...Laurel, NJ, was born with a lower jawsignificantly smaller than her upper jaw. This misalignment makes eating andeven speaking difficult since her teeth do not meet and her tongue is in anawkward position. Howmedica Leibinger, the company that manufactures DynaForm, has chosenTemple as one of only...Controlling Collagen Levels May Be Key To Fighting Organ Failure Caused By High Blood Pressure
...nto the study withenlarged hearts appeared to have smaller hearts on a follow-up echocardiogram. Diez says the ability to easily measure collagen levels could lead todrugs that help prevent organ damage in people with high blood pressure. "It isa development which can be anticipated in the immediat...