Prestigious 2004 AAAS Philip Hauge Abelson Prize honors Maxine Singer
...ncemag.org ). AAAS was founded in 1848, and serves some 262 affiliated societies and academies of science, including 10 million individuals. Science has the largest paid circulation of any peer-reviewed general science journal in the world, with an estimated total readership of one million. The non-prof...Next generation body scanner launched by the University of Manchester
...: "This piece of equipment will help us to unravel some of the mysteries of the brain and how it works. For the first time we will be able to see how different parts of the brain communicate with each other and this will be invaluable to many different areas of our research. "The scanner will lead to imp...Hepatitis B viral load, genotype affect liver cancer risk, study finds
...genotypes, or subtypes, of HBV. Although there are some known risk factors for HCC development, it is unclear what role HBV subtype or viral load--the amount of the virus in the blood--might have on cancer development. To determine whether HBV genotype and viral load are associated with HCC risk, Ming-Whe...Faster, less expensive test proven more effective in detecting bladder cancer
... they had evidence of blood in their urine and met some of the risk factors associated with the disease, w...ndard" of diagnostic tests, but can fail to detect some bladder cancers, says Grossman. In this study, the researchers looked at the sensitivity as well as ...Another look finds promising proteomics test is not biologically plausible
...entire spectrum." Furthermore, the researchers say some of the protein peaks were found in regions of the spectra where, for technical reasons, mass spectrometry cannot be sampling proteins, and thus may be simply representing experimental "noise." Such results may come about from such procedural problems...Johns Hopkins scientists receive presidential medals
...ive posts -- for the construction and operation of some of the world's most important astronomical observatories. One of those posts brought him to Johns Hopkins in 1981. "The National Medal of Science is our country's highest recognition of scientific achievement. Through his pioneering work in astrono...No increase in sexual risk taking among gay men in HIV-study
...try thought the vaccine being tested might provide some protection. The vaccine being tested was ultimately shown to be ineffective. "These results are important and reassuring. They demonstrate that gay men can participate safely in HIV vaccine trials without a false sense of security that could lead to...Older doctors less likely to follow current standards of care
... measured, and 13 studies (21 percent) showed that some but not all aspects of a doctor's performance decline with time. "The findings also reflect the substantial environmental changes that have occurred in medicine over the past several decades. Evidence-based medicine has been widely adopted and qualit...Hypothyroidism associated with reduced breast cancer risk
...rmone in women with breast cancer that could offer some prognostic or therapeutic value, perhaps suggestin...land disease on breast cancer has been debated for some time. Other smaller studies have focused on a population of women with several thyroid conditions, s...Uric acid may help reduce effects of spinal cord injury, Jefferson researchers find
...own product found in blood and urine, may help cut some of the potentially devastating "secondary" cellula...whether uric acid treatment could actually prevent some of this secondary damage following such an injury in mice. Uric acid was known to reduce inflammatio...COX-2 product offers good and bad news in 'test tube' strokes
...cardiovascular complications with long-term use of some COX-2 inhibitors are thought to be due to blocking effects of "good" prostaglandins, which are the downstream products of COX activity, potentially leading to heart attacks and strokes. "Defining which prostaglandin pathways are good and which promot...Promising treatments for Huntington's disease identified in UCI study
...single drug given at an effective dose may provide some relief, but only treats one component of the disea... addition, combinations of drugs that each provide some relief from symptoms might be expected to provide even greater relief when in combination. Combinato...New highly active agents against sandfly fever
...unsaturated (alkenyl) bond. Among these compounds, some proved especially active against parasites of the ...Among the quinolines active against leishmaniases, some were also able to block, in vitro, the replication of the retrovirus HIV-1, without manifesting any ...Clot-busting drugs may help detect potentially deadly leg clots
...cant changes at the highest two doses. "There are some groups of people, especially those with deep-vein ... mimic d-dimers," says Dr. Robinson. Adding tPA or some other clot-dissolving drug right before the test may clear up those positives and negatives, he says...Stem cell therapy for spinal injury
...atients with spinal injury. Spinal injury confines some 150 Swedes a year to wheelchairs. The damage cause the loss of movement and sensation below the level of injury. A research team at Karolinska Institutet has now shown using rat models that the introduction of stem cells following such injury is effe...Dialogue & personal example work best for parents in drug talks with teens
...potential health and legal risks of drug use, with some parents even warning about the chances of incarceration for serious drug offenses. Miller-Day says, "Over two-thirds of the persons interviewed reported integrating ongoing socialization efforts into the fabric of their everyday lives as opposed to ...High levels of airborne mouse allergen in inner-city homes could trigger asthma attacks
...tial to be life-threatening, these findings are of some concern," she adds. The researchers report airborne mouse allergen was most likely to be found in homes with cracks and holes in walls or doors, exposed food in the kitchen, or evidence of mouse infestation, such as droppings. Although mouse allerge...Study finds happiness persists, despite illness
...tional response to their new life. In the words of some of Ubel's patients, "What use is there in complain... the effect of illness on mood calls into question some of the ways we use such quality-of-life estimates in policy making and research." In addition to rec...Trial reveals safer and simpler approach to treating children with cystic fibrosis
...concludes: " Smyth and colleagues' report provides some useful insights into the safety and efficacy of once-daily administration of aminoglycosides in patients with cystic fibrosis. However, we need larger and longer studies that include adequate numbers of children and adults. Future studies should eval...Newly identified gene cluster on mouse X chromosome provides insights into fertility
...m to mature and become sperm." "Another thing that some Rhox genes could be doing is regulating the production of proteins within Sertoli cells that allow the neighboring germ cells to survive," Wilkinson says. "If you knock out Rhox5, many more germ cells die than would normally." The researchers do not ...