Magnetic bracelets reduce the pain of osteoarthritis
...not be certain whether their findings are due to a specific effect of magnets or a placebo effect. But, whatever the mechanism, the benefit from magnetic bracelets seems clinically useful. The (one-off) cost of bracelets (around 30-50 or $58-$96), also compares well with that of painkillers, such as paracetam...Research in yeast yields missing link in DNA maintenance machinery
... cells. They found that INO80 proteins recognize a specific form of histone protein called gamma-H2AX that acts as a "flag" or "code" to direct DNA repair proteins to DNA breaks. Once attached to the histone protein, the INO80 proteins most likely loosen the histone grip on DNA so the repair machinery can gai...Major step forwards for vaccine against cervical cancer
...ells. The vaccine developed by Bungener, induces a specific immune response against these two proteins. To te...e animals produce cytotoxic T-lymphocytes that are specific for E6 and E7 and prevent the tumour from growing further. Even mice that already had a tumour could...Scientists discover enzyme crucial to the transportation of proteins within cells
...s to proteins resulting in their transportation to specific cellular locations where they perform essential functions. This process known as palmitoylation is extremely important for the normal functioning of the nervous system where proteins are transported rapidly within nerve cells known as neurons. Until...How platelets help cancer invade other tissues
...es that modulate platelet activity will need to be specific for the pathological tumor cellplatelet interaction, without effecting normal platelet function. Platelet-specific integrin inhibitors like Integrilin fall into this category. The study also suggests that drug-mediated inhibition of platelet-derived ...Brain region identified that controls collecting behavior
... studied 86 people with focal brain lesions - very specific areas of brain damage to see if damage to particular brain regions could account for abnormal collecting behavior. Other than the lesions, the patients' brains functioned normally and these patients performed normally on tests of intelligence, reaso...New clue to nerve growth may help regeneration efforts
... development of developing rats. During this step, specific nerves begin connecting between what will eventually be two sections of the brain. Because the accurate extension of these nerves requires semaphorin 5A, Kantor was able to identify key molecules that interact with it. He found that CSPGs bind semap...To help your mind, take steps to help your heart, study says
...s, and observational studies based on trends among specific populations. Taken together, the analysis suggests...n cholesterol drugs called statins haven't shown a specific effect on dementia, but follow-up periods in such studies have been short. There's o...Anger, negative emotions may trigger stroke
...ive medications to lessen the risk of stroke among specific high-risk groups might also be studied." The study examined 200 people who were hospitalized with an ischemic stroke or a transient ischemic attack (mini-stroke). Ischemic stroke is caused by reduced blood flow to the brain. It is the most commo...Brain imaging reveals new language circuits
...e, 19th Century neurologists, noted that damage to specific cortical areas, which came to bear their names, produced primarily language production or language processing disorders, but not both. A large bundle of nerve fibers was found to connect Broca's and Wernicke's areas, and damage to this pathway also p...Study finds lemons, lilac among top 10 smells that predict Alzheimer's Disease
...p duration of five years. Inability to identify 10 specific odors (derived from the broader study) proved to be the best predictors for Alzheimer's Disease: strawberry, smoke, soap, menthol, clove, pineapple, natural gas, lilac, lemon and leather. "Narrowing the list of odors can potentially expedite screen...Study suggests Akt3 protein is key to melanoma's resistance to chemotherapy
...acids, which can be made to reduce the amount of a specific protein produced by a cell disrupting the synthesis of the protein. In Robertson's study, the siRNA were designed specifically to target Akt3. In addition, he put back the PTEN protein in the melanoma cells. This restarted the normal signals triggeri...Fred Hutchinson receives $9.7 million to lead early detection consortium
...genes. This research may help tailor biomarkers to specific risk groups and identify which biomarkers best indicate the subtle biological changes associated with early cancer development. Co-principal investigator Amanda Paulovich, M.D., Ph.D., an assistant member of Fred Hutchinson's Clinical Research Di...Drug to treat ADHD has similar effect on children with reading disorders
...on, which relates to the amount of blood flow to a specific brain region in response to a cognitive task. ADHD is characterized by inattention, but previous neuroimaging studies have examined the brain dysfunction associated with impulsivity. "This is one of few studies that used a test for attention rathe...Selective coatings create biological sensors from carbon nanotubes
...s that alter their fluorescence in the presence of specific biomolecules could generate many new types of implantable biological sensors, say researchers from the University of Illinois at Urbana-Champaign who developed the encapsulation technique. In a paper accepted for publication in the journal Nature Ma...Breast cancer may be 'uniquely sensitive' to inhibitors of PI3K pathway
...of breast cancer patients have an abnormality in a specific cell signaling pathway, drugs that target differen...m newly diagnosed patients can be tested for their specific PI3K pathway abnormality in order to find a drug that zeroes in on what may be the cancer's Achilles...Brain can be trained to process sound in alternate way, study shows
...ed groups of neurons that had become selective for specific volume levels -- they fired only at those levels and were quiet otherwise. This physiological change in the brain, called "plasticity," has been widely observed in humans and animals who have learned new skills. Then came the breakthrough discovery: ...Another step towards understanding the causes of narcolepsy
...hat the functional autoantibody is a sensitive and specific marker for human narcolepsy and might lead to a clinically useful assay for diagnosing narcolepsy Identification of the target of the autoantibody and a better understanding of its long-term effects could open up new possibilities for diagnosis and m...Screening for genital herpes should be targeted
...wards." "Screening should be done cautiously in specific populations," said Dr. Guerry. "What you're testing for is a chronic, incurable STD ... You've got to make sure screening is doing more good than harm," Dr. Guerry said....NIH panel issues State-of-the-Science statement on end-of-life care
...any persons at the end of life. The panel cited as specific problems with the benefit the eligibility requirement of a prognosis of six months or less to death, the forced selection of either skilled nursing or hospice care for patients entering nursing homes from hospitals, and limits on certain therapies su...