Gene for age-related macular degeneration discovered by Yale researchers
...he first study to identify a common variant of the specific gene being associated with AMD," said Hoh. "Caucas...that we used many more genetic markers to find the specific gene and variation," said Hoh. "Past research has involved collecting family data that pinpoint a re...2005 Basic Research in Periodontal Disease Award
...esis that bacterial protease inhibitors can act as specific antimicrobials, the group has developed close collaboration with a biotechnology company, Medivir. This partnership aims to determine molecular targets for protease inhibitor design using a genome-screening approach. In the case of bacterial virulenc...Study finds indoor allergen levels vary, cockroach allergens cause more asthma symptoms
...rchers also found that exposure and sensitivity to specific allergens depend greatly on the type of housing and location. Cockroach allergens were common in apartment buildings while dust mite allergens were more often found in houses. Cockroach allergen levels were highest in the Bronx and New York City, whi...Emotional memory study reveals evidence for a self-reinforcing loop
...the neutral pictures, and this recall was based on specific recognition of the pictures. This recall was assoc...l as how much detail is remembered, to explore the specific interactions among brain structures in processing emotional memories. They also plan to analyze acti...Researchers close in on breast cancer vaccine
...like a human immune system. The researchers loaded specific cells in the mice with mammaglobin-A antigens and ...strated that the vaccine-primed immune response is specific to mammaglobin-A antigens," Mohanakumar says. Breast tumors with mammaglobin-A antigens on their sur...Computational tool predicts how drugs work in cells, advancing efforts to design better medicines
...bility to select and develop compounds that act on specific cellular targets has just gained a computational ally -- a mathematical algorithm that predicts the precise effects a given compound will have on a cell's molecular components or chemical processes. Using this tool, drug developers can design compou...Simple question from your doctor can help identify your risk for breast cancer
...were asked about their family histories and if any specific patient characteristics affected whether or not the discussion took place. As disparities were observed between minority and white women, it is suggested that minority women at increased risk for breast cancer may be at particular risk of not being ...Serum sodium level is a major predictor of a poor prognosis for heart failure patients
...Addison's disease. Sodium must be maintained at a specific concentration in the blood and the fluid surrounding the body's cells for the body to function properly....Proteins found in urine of pregnant women could help diagnose preeclampsia
...archers at Yale School of Medicine have found that specific substances in the urine of pregnant women could se...ate the ratio for the presence or absence of three specific proteins that are normally secreted by human placenta. They examined samples of urine and blood from...Studies underscore genetic involvement in nicotine addiction & aggressive hostility
...t might be linked to another yet unknown gene with specific and functional aspects. Says Hennig, "Linkage means that both genes are transmitted together due to their being close neighbors on the same chromosome." The researchers measured genotypes dubbed AA, AC and CC. The "AA" genotype was associated with ...MRI proves useful in assessment of suspected breast cancer patients
...t MR images, which were acquired and analyzed in a specific way, can help identify if a lesion is benign or malignant and can show cancers that would otherwise be missed. "This is the first time a prospective study has been done that shows that MRI (using a contrast agent) can work in a real life community ...Mayo Clinic develops first genomic-based test to predict stroke from ruptured brain aneurysm
...ng The Mayo researchers are the first to identify specific genetic variations or "polymorphisms" associated w...erimental blood test researchers developed detects specific variations in the gene that encodes an important blood vessel-relaxation protein. Dr. Khurana notes ...Potential treatment for Fragile X Syndrome demonstrated in fruit fly model
...e symptoms of the disorder using drugs that dampen specific neuronal overactivity. Their findings appear in the March 3, 2005 issue of Neuron. Characteristics of Fragile X in people include an average IQ of about 50, deficits in certain types of short-term memory, autistic behavior, sleep problems, hyperactiv...Men more likely to get screened for prostate cancer than colon cancer, U-M study finds
...ning test for prostate cancer, called the prostate specific antigen, or PSA, test, is more controversial. Experts continue to debate what PSA level is cause for follow-up, and research suggests the test has not led to fewer deaths from prostate cancer. "Colon cancer screening is proven to be effective at redu...Both inherited traits and tumor mutations affect response to treatment of leukemia
...GSTM1 and TYMS, are likely linked to resistance to specific cancer drugs, and that treatment of ALL might be improved in higher-risk patients if therapies were modified to take these inherited risk factors into account. Other authors of this paper are Cheng Cheng, Wei Liu, Shinji Kishi, John T. Sandlund, Jef...Other highlights in the March 2 JNCI
...ce between screening tests to recommendations of a specific test and to the option of doing both tests, and comparing two methods of distributing the FOBT kits. He questions whether theoretical models of screening behavior would predict the surprising finding that subjects who were given a choice between scr...'Smart' immune cells kill more cancer
...atients have T-cells in their bone marrow that are specific to their tumor. Myeloma strikes close to 16,000 Americans annually and kills 11,300. Other participants of this research include William Matsui, Paolo Serafini, Rebecca Carbley, Gladys Tan, Hyam Levitsky, and Katherine Whartenby from Johns Hopkins; a...More training needed to care for growing geriatric population
...as of 2003, that only 27 of the 91 specialties had specific geriatric training requirements. And these require...ties training non-pediatric physicians do not have specific geriatrics curriculum requirements. Yet once these physicians establish their clinical practices, ma...Protein that promotes survival of stem cells might be key to poor leukemia prognosis
...t become increasingly specialized and then produce specific types of blood cells, such as B lymphocytes--immun...r cells produced by HSCs are able to generate more specific cells, such as the immune cells known as B and T lymphocytes. In the Science study, Opferman's te...Schepens scientists regenerate optic nerve for the first time
...e first lock, they found, was the turning off of a specific gene BCL-2 which, when turned on, activates grow...e use of a mouse line carrying mutations of "glial specific genes" that lead to the reduced "glial scar" formation. By unlocking the regeneration with the first...