MGH researchers find way of regenerating cells key to hearing
...ntly more numerous than in normal mice at the same stage of development. These additional cells retained the distinctive appearance of hair cells, performed functions characteristic of normal hair cells and appeared fully able to form proper connections with nerve cells. In addition, hair cells in the mo...Colorectal cancer screening underutilized
...iversity reviewed the screening history and cancer stage of 5,806 elderly patients diagnosed with colorecta...ore than six months prior to diagnosis had earlier stage and presumably more treatable disease. The authors conclude, "we have highlighted the underuse of co...Research offers hope of new treatments for liver damage 'plague'
...anced liver fibrosis (scarring) and cirrhosis (end stage scarring of the liver). Currently, we have no effective treatment for liver cirrhosis which is associated with internal bleeding, liver failure and the development of primary liver cancer. There is a huge imperative to develop new approaches to the t...Substance in urine predicts development of preeclampsia
...D., Director of the NICHD. "This finding sets the stage for the development of a test to screen women for high risk of preeclampsia. Once these women are identified through such a test, we can target studies to find effective ways to prevent its progression or to keep the most dangerous complications fro...NIH action plan charts future challenges for liver disease research
... often fatal and difficult to diagnose at an early stage when it is easier to treat and possible to cure by surgery. Simple and accurate diagnostic techniques could detect liver cancer early and improve patient survival. Developing standardized and objective diagnostic criteria of major liver diseases ...Poor response to chemotherapy does not mean poor outcome for patients with rare breast cancer
... six clinical trials that treated 1,034 women with stage II and III invasive breast cancer (lobular or ductal) with primary chemotherapy in order to shrink their tumors before surgery. "We always have thought that a poor response to chemotherapy always indicated a worse prognosis, but that is not true for ...Combining hormones with external, internal radiation helps high risk prostate cancer patients
...Gleason score, a high PSA score and/or an advanced stage doctors have been adding hormone therapy and external beam radiation therapy to the treatment plan to try to increase survival rates. In this study, doctors studied nearly 200 men with high risk prostate cancer over eight years to see if adding ext...Cervical cancer treatment depends on patient age
... older. Their study showed that regardless of the stage of tumor development, elderly patients were likely... were not the only factors to affect survival; the stage of tumor advancement and the presence of other medical conditions also influenced outcomes. But, thi...Sudden death from stress linked to wonky signals in the brain
... from UCL's Institute of Neurology says: "The next stage of our research is to explore how signalling from the brain becomes uneven. It seems that emotions and stress may particularly activate the right hemisphere in the upper brain, but this is usually balanced out into a symmetrical signal produced lowe...Shire receives US FDA approval of EQUETRO (TM) for bipolar disorder
...d in 2004. It demonstrates the quality of our late stage pipeline and the competence of our R&D team. Approval of EQUETRO enables Shire to bring its established expertise in CNS to this large and increasingly recognized market." Richard H. Weisler, M.D., primary investigator of two EQUETRO clinical trials...Broad-based vaccination of wild mice could help reduce lyme disease risk in humans
...e larval form of the blacklegged tick, the crucial stage during which a tick becomes infected with B. burgdorferi. Normally, uninfected tick larvae pick up the bacterium the first summer of their two-year life cycle while taking their first blood meal from infected small animals, such as the white-footed m...Hypertension: On the Pill? Tell your dentist
...if diastolic pressure is 9099 you are experiencing stage 1 hypertension. If systolic pressure is 160 or hig...if diastolic pressure is 100 or higher, you are in stage 2 hypertension. Hypertensive patients have a few things they should be aware of at the dental office...'Signal' identified that enables malarial parasites to target blood cells
...ded pool of major candidate targets to block blood stage infection as well as complex disease pathologies associated with acute and severe malaria. ...NIH panel issues State-of-the-Science statement on end-of-life care
...d-of-life research, important aspects of this life stage remain poorly understood, according to a panel convened by the National Institutes of Health. The panel found that for many Americans, a lack of continuity of care and poor communication between healthcare practitioners, patients, and family members...Cell marker identifies patients who are more likely to respond to taxol
...which is commonly used before or after surgery for stage I-III breast cancers, even though only a subset of women ultimately benefit from this treatment. Patients whose breast cancer cells have lost their ability to express a protein called "tau" are twice as likely to have a good response to Taxol treat...Marine snail study gives insights into human brain
... memory, protein synthesis may occur at an earlier stage in memory formation than was thought before. Then the questions are: What proteins are being synthesized, where are they being synthesized and what are they doing once they're synthesized? We will use the Jacob Javitz Award to try to answer these que...Novel drugs help solve Gleevec resistance
...ppearance of all findings consistent with advanced stage CML, and return of blood counts to normal), while two patients showed no evidence of leukemia. Two other patients had their CML downgraded to "chronic." Additionally, of the 11 patients, four have had a major "cytogenetic response" (defined as elimin...'Sobering' disparity: African-Americans receive less compensation for job-related back injuries
...ded to better understand the disparity. "The first stage of solving a problem is identifying it. We're at that problem identification stage. Of course we now need more detailed information so that we can move toward solving the problem."...New biopsy technique helps assess breast cancer's spread
... axillary lymph nodes. If we can use ultrasound to stage the axilla and identify metastatic disease, we can save some women the additional surgery," says Alexis Nees, M.D., clinical assistant professor of Radiology at the U-M Medical School. Nees will present the results at the RSNA meeting. The technique ......lted in increased tumor disease and often a higher stage of the disease." Smokers should consult their doctors to determine at what age CT screening should begin, but this data provides the basis for such recommendations. With annual screening, there is a 76-78 percent chance of a smoker's lung cancer bein...