GlaxoSmithKline Drug Discovery and Development Award 2002
...e to being broken, both by the acid in a patient's stomach and by an enzyme, called purine nucleoside phospho...e sugar analog and the purine base is resistant to stomach acid and purine nucleoside phosphorylase," said Dr. Sartorelli, the Alfred Gilman professor of pharm...'Virtual stomach' reveals pill's path
...release tablets that are designed to remain in the stomach for hours while slowly releasing medicine. The re...w the pills break down and release medicine in the stomach are largely unknown. The new "virtual stomach" has shown that tablet motion and mixing are highly s...Most definitive study of its kind shows that sleeping on the stomach increases infant SIDS risk
...ive study of its kind to show that sleeping on the stomach increases the risk of U.S. infants for Sudden Infa...NICHD. "Other studies have linked sleeping on the stomach with Sudden Infant Death Syndrome, but the Chicago Infant Mortality Study makes the strongest case t...Experienced surgeon reduces complications from minimally invasive 'stomach staple' surgery
...reduce complications from a new minimally-invasive stomach staple surgical technique that is quickly becoming...erted into the abdominal cavity. Part of the upper stomach is stapled to create a small pouch and the small intestine is rerouted and connected to the new pouc...Swallowing a tiny imaging capsule aids in diagnosis of obscure gastrointestinal bleeding
...camera is inserted down the esophagus, through the stomach and into the first third of the small intestine. The researchers found that wireless capsule endoscopy identified potential sources of bleeding in 70 percent of the patients, compared to 45 percent with push enteroscopy. While the Miami study reveal...Costs for surgical treatment of GERD not offset by savings on medications
...toms of GERD are caused when the valve between the stomach andesophagus allows stomach acid to leak into the esophagus. Some people with GERD opt for surgery when drugs do not help enoug...Multiple characteristics of HAART affect adherence
.... The requirement that pills be taken on an empty stomach was viewed as a greater barrier to adherence than other dietary restrictions, according to survey responses. Having no food restrictions or requirements was rated the highest. - Number of prescriptions/copays. Patients rated fewer number of prescrip...Important information to consider about non-systemic cholesterol lowering agents
...ur doctor if you have trouble swallowing or severe stomach or intestinal problems. Side effects may include constipation, indigestion and gas....Georgia Tech researchers developing biomechanic device to grow arteries for bypass surgery patients
...out 3-7 mm diameters in size and located below the stomach the device has shown to be effective in lengthening arterial tissue in pigs by as much as 30 cm enough for a patient to undergo at least two CABG procedures, researchers say. The patented process has been coined "distraction angiogenesis" by lead s...New drug linked to fewer deaths among kidney patients undergoing hemodialysis
...ng calcium carbonate (a main ingredient in popular stomach relievers) and calcium acetate. However, some patients using these calcium-based binders develop hypercalcemia, high calcium levels, prompting a search for other types of phosphate binders. Recently, a non-calcium phosphate binder, Renagel, has com...JCI table of contents, November 4, 2002
...involuntary functions of organs such as the heart, stomach and intestinesare regulated by the autonomic nervous system. This system is divided intotwo parts - the sympathetic nervous system (SNS) and parasympathetic nervoussystem (PSNS). The SNS controls our body's reactions during "fight orflight" situation......involuntary functions of organs such as the heart, stomach and intestinesare regulated by the autonomic nervous system. This system is divided intotwo parts - the sympathetic nervous system (SNS) and parasympathetic nervoussystem (PSNS). The SNS controls our body's reactions during "fight orflight" situation...Genotyping targets individuals at high risk for H. pylori-associated stomach cancer
...c genetic polymorphisms are more likely to develop stomach cancer than others. The findings appear in the Nov... infected with H. pylori have an increased risk of stomach cancer, but many of these people will never develop the disease. Past studies have suggested that di...Heart gone haywire blamed in some sudden infant deaths
...requency of SIDS: 1) don't place a baby on his/her stomach to sleep, 2) don't expose a baby to cigarette smoke and 3) don't cover a baby with heavy blankets. He says medical examiners must begin to collect and store tissue in a way that enables a molecular autopsy in sudden infant deaths....Generalized anxiety disorder linked to peptic ulcer disease
...rgy. A peptic ulcer is a sore in the lining of the stomach or small intestine. More than 25 million Americans suffer from an ulcer during their lifetime, according to the Centers for Disease Control and Prevention. Goodwin and Stein found that generalized anxiety disorder was associated with a significantly ...Moderate physical activity is critical for reducing the risk of chronic disease in older women
...pple-shaped" people who store their fat around the stomach are at higher risk for conditions such as diabetes, hypertension and stroke than "pear-shaped" people who store their fat in their buttocks and thighs, visceral obesity is not necessarily correlated with body shape, McTiernan said. The only accurate ...Ibuprofen could reduce cardioprotective effect of aspirin
...taken together increases the risk of bleeding from stomach ulcers. So this combination may not only reduce the benefits of aspirin, but may also increase the risks of side effects."...Study provides new evidence that cranberry juice may help fight heart disease
...infections and may reduce the risk of gum disease, stomach ulcers and cancer. In the current study, Vinson measured cholesterol levels in nineteen subjects with high cholesterol after a fasting, baseline blood sampling, followed by monthly samplings. Ten of the subjects were given cranberry juice with artif...Colonoscopy far more cost-effective against colon cancer than promising Cox II drugs, study predicts
...ox-II's sister enzyme, Cox-I, they don't cause the stomach upset that other painkillers, like aspirin and ibuprofen, can create when they inhibit both kinds of cyclooxygenase. Those two properties have made the drugs attractive for treating chronic joint disorders, and have raised hope that they could be ef...Could a mandated food additive aimed at better fetal development be a risk for seniors?
...or eggs), and those taking medications which block stomach acid production and thus B-12 absorption, are at h...crew shaped bacterium responsible for a variety of stomach ailments, including gastric and duodenal ulceration and atrophy of the stomach lining, occurs quite ...