New test can identify patients who may suffer serious late toxicity from radiotherapy
...D8 only. "Furthermore, the test could be used to stratify patients in future dose escalation trials. We intend to use it for stratification in Phase III trials, and as a factor for exclusion in Phase I and II trials. A retrospective finding of our study was that patients with breast cancer who received ta...Molecular test proves to be effective in measuring remission and relapse after cancer treatment
...als. "Our results tell us that PCR can be used to stratify patients according to their level of remission by measuring the number of cancer cells that remain after patients are in cytogenetic remission, and those numbers correlate with how likely it is that a patient's disease will progress," Radich said. "W...Air rather than oxygen for babies requiring ventilation after delivery
... be investigated. Future trials should include and stratify for premature infants". In an accompanying commentary (p 1293), Georg Hansmann (Stanford University, USA) concludes: "The evidence for mortality reduction with air is striking and will have widespread impact on the management and outcome of depressed...Study shows drugs such as Vioxx and Celebrex were widely over-used long before recent problems
...ons and compared them to treatment guidelines that stratify patients into different treatment groups based on the risks of gastrointestinal symptoms. The guidelines recommend that patients with "very low risk" of GI problems (31% of patients in this study) or "low risk" (42%) receive traditional NSAIDs. Pa...Sequential MDCT sufficient for determining possible risk of coronary artery disease
Sequential MDCT offers an adequate way to stratify which patients have calcium build-up in their coronary arteries--a possible risk factor for developing coronary artery disease, a new study shows. "Most equipment manufacturers recommend a sequential MDCT examination for the detection of coronary a...... both operations. "We feel that it is essential to stratify surgeon outcomes by risk to be fair to surgeons and prevent them from taking on only the easiest and least severe cases," say the authors. "The public is now able to see the outcomes of individual surgeons and can be reassured that all are performing...