Emotion-regulating protein lacking in panic disorder
...nin receptor is reduced by nearly a third in three structures straddling the center of the brain. The finding is the first in living humans to show that the receptor, which is pivotal to the action of widely prescribed anti-anxiety medications, may be abnormal in the disorder, and may help to explain how genes ...Ultrasound-guided liposomes boost imaging, target drug/gene therapy
...echnique used to examine and measure internal body structures and to detect body abnormalities. In cardiology, u... used to see inside the heart to identify abnormal structures or functions, for example, to measure blood flow through heart and in major blood vessels. Lipos......ss the outer membrane of cells, but they do affect structures within cells. One of the main effects seems to be calcium release from a cellular structure called the endoplasmic reticulum. "In a nanosecond, we cause this major physiological event in the cell," says Vernier. "It's completely indirect and remote,...The physics of films, butterflies, banknotes and rainbows
..., for example are trying to copy various nanoscale structures that appear on butterflies and moths to see if the...rsity describes, the interaction of light with the structures produces microscopic arrays of colour that overlap to produce a third colour. This could provide a c...Cholesterol drugs may lower risk for mental impairment after stroke
...d to identification of changes in brain regions or structures that predict cognitive impairment....Laser method identifies, counts toxic molecules
...oviding key information about surface reactions or structures for many applications, such as improving solar cell efficiency....Aromatase inhibitors: A promising new treatment for endometriosis
...gical endoscopic procedure to visualize the pelvic structures at the beginning and end of the study. In all patients, a second-look laparoscopy showed the endometriosis had either disappeared or was strikingly reduced. The study also showed a very significant reduction in pain associated with endometriosis....Targeting cell fusion as possible way to repair organs, deliver cancer vaccines
...mple, they repair the liver by fusing the cellular structures in the liver," Dr. Russell explains. "We may be able to exploit this new biofusion technology by genetically engineering stem cells so they fuse quickly and efficiently to a target site, and thereby direct the stem-cell repair process."...Clip device accomplishes endovascular, non-surgical repair of faulty heart valve
...t are intended to repair or replace malfunctioning structures of the heart without surgical intervention. Recovery times will be reduced from weeks to just days," he adds....Loss of smell linked to key protein in Alzheimer's disease
...s and the presence of excess tau proteins in brain structures important for smelling. Additionally, the genetic...d a significant amount of neurofibrillary tangles, structures also linked to Alzheimer's disease. No test currently exists for the detection of Alzheimer's diseas...A new hypothesis about Alzheimer's disease
...ases are caused by the misfolding of proteins into structures that lead them to cluster together, forming microscopic fibril or plaques, which deposit in internal organs and interfere with normal function, sometimes lethally. In the case of Alzheimer's, these fibrils kill nerve cells in areas of the brain that ...Radiation therapy effective for some patients with recurrent cancer after radical prostatectomy
... and seminal vesicle invasion [cancer spreading to structures near the urinary bladder of males] were significant predictors of disease progression despite salvage radiotherapy. Yet we demonstrated that subsets of patients with high-grade disease and/or a rapid PSADT who were thought to be incurable could still...UCSF scientists show prion shape affects nature of infection
... is to understand what distinguishes the different structures in the different prion strains, and how these different structures change a prion's properties -- including how dangerous they are." In their laboratory at UCSF's Miss...Inhibitors prevent aggresome formation associated with some forms of ALS
...rophic Lateral Sclerosis (ALS), and aggresome-like structures formed by mutant SOD1 are associated with the dise...LS animal models, mutant SOD1 forms aggresome-like structures in motor neurons and astrocytes. It was hypothesized that these aggresomes are the cause of toxicity...Genome sequence reveals leaner, meaner intestinal parasite
...s currently no effective treatment--is missing key structures normally found in similar parasites, say researchers supported by the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health. The results of their genome sequencing project, now available in the online...Mayo Clinic researchers discover gene mutations that 'ignore' stress, lead to heart failure
...t the mutations create an abnormality within vital structures of heart cells known as the ATP-sensitive potassium channel. Potassium Channel at a Glance In healthy people, the potassium channel synchronizes the proper balance of potassium and calcium flow in the heart. Calcium is needed for the heart's contr...Latest cancer research features small molecule therapy, and the preventative benefits of sunshine
...ding to the cMyc quadruplex, he said. G-quadruplex structures are four stranded DNA secondary structures. Certain G-quadruplexes regulate transcription of specific oncogenes, including cMyc. The quadruplex cluster that includes cMyc also includes VEGF, a growth factor that regulates development of blood vessel...Surgical skill increases survival for oesophageal cancer surgery
...entres lack specificity and may be due to inherent structures and processes in place in 'bigger' hospitals". "It would make more sense to develop specialized, regional centers for all complex surgical procedures", said Mr Dutta Roy....OHSU researchers uncover genes involved in early stages of Alzheimer's disease
...han in normal mice," Reddy said. "Mitochondria are structures located in the cytoplasm of cells that produce ene...r than normal levels of this protein can result in structures in the brain called beta amyloid plaques, which are thought to be either a cause or an effect of Alz......inst the host's antibodies. These sugars are large structures that apparently block the way of human antibodies that would otherwise fix on to the virus, without hindering these envelope proteins in their function of attaching the virus to the host cell. These results open the way to potential ways of tackling ...