Tag: "subtype" at medical news

HIV-1 spread through six transmission lines in the UK

...y College London (UCL) scientists found that HIV-1 subtype B spread through the UK via at least six large tra...sex with men, suggesting separate introductions of subtype B strains into the UK in the early-to-mid 1980s. After an initial period of exponential growth in in...

Gender gap for lung cancer rates narrowing

...ere are other gender-linked differences, including subtype of lung cancer and survival rate. "Traditionally, lung cancer has been viewed as a disease of older male smokers, but that is not necessarily the case," said the study's author, Gregory P. Kalemkerian, MD, University of Michigan Medical Center, An...

'EuroVacc 02' HIV vaccine trial begins in February 2005

... in February 2005. These vaccines are based on HIV subtype C, which is prevalent in China, India and sub-Saha...ty of Regensburg based on a representative Chinese subtype C isolate CN54 jointly developed with Professor Yiming Shao from the CDC Beijing. The plasmid was co...

Hepatitis B viral load, genotype affect liver cancer risk, study finds

Infection with a specific subtype of hepatitis B virus (HBV) and a high viral load a...s for HCC development, it is unclear what role HBV subtype or viral load--the amount of the virus in the blood--might have on cancer development. To determine ...

Other highlights in the February 2 JNCI

...te megakaryocytic leukemia (AMkL), the predominant subtype of AML in these children, may be responsible for the survival difference. Jeffrey W. Taub, M.D., of Children's Hospital of Michigan and the Barbara Ann Karmanos Cancer Institute, both in Detroit, and colleagues found that a protein encoded by the GAT...

NIAID begins enrolling volunteers for novel HIV vaccine study

...ened adenovirus that serves as a carrier for three subtype B HIV genes. Subtype B is the most prevalent HIV subtype in the regions of the study sites. Adenoviruses are among the main causes of upper respiratory tract...

Pegaptanib provides benefit for neovascular age-related macular degeneration

...scular AMD, regardless of the size or angiographic subtype of the lesion or the baseline visual acuity. The rate of injection-related adverse events represents a potentially modifiable risk but necessitates vigilance, the authors caution. The Massachusetts Eye and Ear Infirmary (MEEI) in Boston participated...

Triple-drug therapy promising against African HIV subtype

... in the United States and Europe against one HIV-1 subtype appear to be effective in South African patients infected with a different HIV-1 subtype who also have tuberculosis (TB) or Kaposi's sarcoma (KS), according to a study published in the Feb....

Fred Hutchinson receives $9.7 million to lead early detection consortium

...markers also could be used to classify the genetic subtype of the cancer so that treatment could be better tailored to the individual. Geneticist and clinical oncologist Amanda Paulovich, M.D., Ph.D., of Fred Hutchinson's Clinical Research Division, is co-principal investigator of the award. H...

Certain types of schizophrenia may be linked to summer birth

CHICAGO Patients with deficit schizophrenia, a subtype of schizophrenia characterized by "negative" symptoms, such as blunted speech and expression, lack of emotional response, and apathy, are more likely to have been born in the summer months, according to an article in the October issue of The Archives...

Different subgroups of alcoholics respond differently to serotonin-acting medication

...r study clearly suggests that there may be ways to subtype alcoholics, and that these different subgroups of alcoholics may respond differently to the same treatment," said Dundon. "Numerous classification schemes have been proposed to differentiate types of alcoholics. Our study supports the usefulness of...

Researchers find strong familial tendency in rare form of lymphoma

...urface of Waldenstrom's tumor cells may indicate a subtype of the disease. Waldenstrom's is a malignancy of white blood cells called B cells, which fight disease by producing antibodies against viruses, bacteria, and other foreign substances. Usually diagnosed in people over age 65, the disease has been thou...

Male and female smokers have similar lung cancer risk

...n the possibility that the risk of some particular subtype of lung cancer may be higher in women than in men, though overall risk is not different. "[I]n the context of what is now a substantial body of prospective evidence, it becomes very difficult indeed to argue the case for inequality of smoking-related...

Gene mutations predict which lung cancers will respond to Iressa

...atients whose tumors responded to Iressa were of a subtype of NSCLC called bronchoalveolar cancer. Subsequently the researchers analyzed samples from 25 other NSCLC patients who had not been treated with Iressa. Two of those samples had mutations identical to ones found in Iressa-responding patients, and the...

HIV: A sugar shield to evade host defences

..., thus appear highly conserved and stable from one subtype to another. However, the env gene, which codes for the virus's envelope proteins, targets of the host's immune system antibodies, appears to contain positively selected sites: at the point on the genome where this gene is located, the mutations woul...

Estrogenlike drugs may eventually help postmenopausal women with weight gain

...tor are Eα and ER. However, the role of each subtype in the effects of estrogens on and food intake and body weight gain has not been conclusively determined. Mice with a genetic knockout of the gene for Eα show an increase in fat tissue accumulation compared to wild-type mice, suggesting a role...

Lung cancer now leading cause of cancer death in women

... more likely than men to develop adenocarcinoma, a subtype of lung cancer, than are men. Adenocarcinoma, once a rare type of lung cancer, is now the most common type of lung cancer and is less associated with smoking than other types of lung cancer. Adenocarcinoma is the most common form of lung cancer pres...

Latest cancer research features small molecule therapy, and the preventative benefits of sunshine

...Pax8/PPARgamma fusion genes common to a follicular subtype of thyroid tumor. The unaltered peroxisome proliferator-activated receptor gamma (PPARgamma) found in anaplastic thyroid tumors is apparently in tact, providing a way by which RS-5444, a novel drug therapy, can unlock mechanisms leading to reduced t...

Vaccine development against influenza A (h5n1) virus 'should be made a priority'

...number of transmissions of avian influenza A virus subtype H7N7 to people directly involved in handling infected poultry, and we noted evidence for person-to-person transmission. Our data emphasise the importance of adequate surveillance, outbreak preparedness, and pandemic planning". In a Research letter ...

Hair dye use increases risk of non-Hodgkin's lymphoma

...hair coloring product use appears to vary based on subtype of the disease." There has been a worldwide increase in NHL cases and Connecticut is one of those areas with a confirmed increase. Little is known about the origin and the risk factors responsible for the increasing incidence of the disease. Zhen...

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