Digital Speech Analysis Tests Sobriety
...dered a leader in the study ofacoustical analysis, synthesis and perception of speech. Chin is apsychology postdoctoral student specializing in linguistics. The two researchers approached Cummings after hearing about herthesis work at Georgia Tech, published in 1992, on how <AHREF="http://www.ece.gatech.e...Fertilization Protein Structure To AID in Leukemia Treatment
...side the egg from the building blocks of DNA. The synthesis reaction requires a specialized protein, known as ADP ribosyl cyclase. It is this protein that has been studied by the researchers at Scripps. By preparing crystals of the protein and scattering x-rays off them, a three-dimensional image has been r...Chemist Turns To Self-Assembly To Create New Drugs
...emistry atStanford University and an expert in the synthesis of biochemicaland medicinal compounds. "The Miller group has clearly shown thatthis approach makes sense and that it can work. Nature is a hugebiodiversity generator, and they've found a way to mimic thisprocess in the laboratory." Miller's tech...Tighter Chemical Binding = Better Meds
...ed to potentialdrugs that can regulate the natural synthesis of insulin for diabetics ina gene therapy approach involving implanted cells. Vast Increases in Computer Speed Vast increases in computer speed in recent years make it possibleto perform complex computations of chemical processes in minutes instead...Researchers Synthesize Compounds For New Class Of Antibiotics
...sity's participation in the project. "The chemical synthesis provides uswith the means for generating the mater...to takemyxopyronin and make it more drug-like. The synthesis was designed to allow usto make many analogs--many different candidates--so that doctors can choose ...Steroids May Reverse Loss Of Substance Tied To Nervous-System Diseases
...ps clarify thesignals that are responsible for the synthesis of myelin," said JonahR. Chan, a doctoral student ...tedthe first technique for observing the continual synthesis of myelin by Schwanncells around axons of neurons. In their new work, researchers added variousform......lyst research, Howard W. Turner, willhighlight the synthesis and screening of catalysts intended for use inmanufacturing a variety of valuable polymers. These catalysts could solve whathe calls "some of the greatest challenges in material science today." Combinatorial chemistry has proven a powerful tool in th......emerging field characterized bythe rapid, parallel synthesis of large "libraries" of organic compounds used for...rug discovery, which have a long lag time fromdrug synthesis to application in the clinic with patients. By contrast,biocombinatorial chemistry is expected to o...Improved Ritalin™ Offers Smaller Doses And Fewer Side Effects
... million, are prescribed Ritalin. Using a new synthesis developed in his lab, University of Pennsylvaniach...have just started ourstudies," he adds. While synthesis of the improved form of Ritalin for treatment of ADHD isready for commercial scale-up, Winkler says,......e theirsynthesis,called the most challenging total synthesis of its time. Previously,physostigminecould only b... Julian's lifetime of achievements in the chemical synthesis of commercially important natural products....New Approach To Attacking Alzheimer's Disease Studied
...inimal interest (among drug makers) in the design, synthesis and development ofbutyrylcholinesterase inhibitors," says the study's co-author Nigel H. Greig,Ph.D., from the National Institute on Aging's Intramural Research Program. TheInstitute's Qian-sheng Yu, Ph.D., is lead author on the paper. While some cu...Sniffing Out The Promise Of Anti-Angiogenesis Therapy
...o being safe, IM862 is a small molecule that makes synthesis andproduction of the peptide fairly simple. It also makes nasal administrationpossible. "It can get over the nasal membrane intact," says Gill, so that morethan 70 percent of the given dose winds up in the bloodstream. Because thepeptide is destroyed...New protocol to develop compound to treat disorders of the central nervous system is more efficient
...ts designof a more efficient, less waste-producing synthesis of a central nervouscompound, still in the early s...ation of hazardous substances. By redesigning the synthesis of this drugcandidate, Lilly has decreased the amount of solvent required, eliminated theuse of a ha...Stress may increase susceptibility to infectious disease
...e stress hormones alter the synthesis and the release ofthe cytokines, the authors explained. Glaser suggests that while in vitro tissue cultures havetaught us much about the immune response, that system mayfunction ...New imaging method in development to show Alzheimer's progression
...antitation." In this paper, his group reports the synthesis of a group ofcompounds that have the solubility properties that are commonly associated witheffective brain imaging agents. "Our compounds are also shown to effectivelylabel amyloid plaques in tissue slices from postmortem AD brain," he adds. "Stu...UB scientists discover role of melatonin in bone formation
...nin may have a significant influence on the rateof synthesis and maintenance of bone in the elderly." Additional researchers involved in this work were Byung-Gook Kim,D.D.S., Ph.D., a Korean visiting scholar, and Wen-Lang Lin, Ph.D., technicalspecialist, both in the Department of Oral Biology in the UB...Wistar scientist receives Arthritis Foundation award
...pment at several key stages by interferingwith the synthesis of prostaglandins, which promote cell communications. Theirstudies show that prostaglandins play an important role in the formation of Tcells, and are likely to impact on disease processes such as the development ofarthritis. The Stewart J. McCracke...Scientists identify new pathway of antidepressant action
...otonin availability, but also greatly increase the synthesis of a key neurosteroid -- 10 to 30-fold. The profou...ost the action of the final enzyme involved in the synthesis of the neurosteroid in the brain. "Each of these three serotonin reuptake inhibitors, or SSRI's, sh...Chemist Percy Julian captures spirit of black history celebration scientist
...Society, of which Julian was a member, honored his synthesis of physostigmine by designating it a National Historic Chemical Landmark. This ACS program honors milestones in the history of chemistry and Julian was honored in ceremonies at DePauw on April 23, 1999.The ACS encourages African American and other mi......ket. Curran's group first developed a free-radical synthesis of camptothecin. Now, the group is applyingthose techniques to making hundreds of candidate derivatives. Several of them, so far tested in mice,appear to share the current products' anti-cancer action but are even more stable - potentiallyallowing a ...