Tag: "targeted" at medical news
Gene vaccine protects mice against development of Her2/neu breast cancer
... for proteins from the cancer cells that are to be targeted
by the animal's immune system. The basis for this new vaccine is an RNA virus called VEE, for Venezuelan equine encephalitis, which in its natural form can cause disease in horses. Researchers at AlphaVax, Inc., a privately held biotechnology company...
Reduced progression of atherosclerosis tied to statin drugs lowering fats, protein
...th coronary heart disease and suggest that therapy targeted
to reduce the active inflammatory state may carry additional benefits," he said. Dr. Michael R. Ehrenstein and colleagues in the department of medicine at University College in London wrote an accompanying editorial. The two a...
Residual tumor cells are a barrier to targeted cancer therapeutics
...) Over the past five years, so-called molecularly targeted
therapies for cancer have held out great promise. ...ber of cancers, chronic treatment with molecularly targeted
therapies has been shown to be effective in the clinic at least in the short-term. Recently, based ...
Surgical treatment of migraines reduces sick days and increases employee productivity ASPS study
...ing the trigger areas for migraines and performing targeted
surgical procedures, we significantly reduced or eliminated their migraines and the amount of time missed from work." Patients in the study were injected with Botox to help determine which muscles in the forehead, or back of the head, triggered their...
Patient protection laws don't favor health providers
...e less frequent and are not very strong. "The laws targeted
most directly to protecting providers are not especially prominent in the overall package of state patient protection laws," writes Hall in the article. One goal of the interviews was to determine whether provider interests were the main impetus for ...
Four teams awarded inaugural translational cancer research grants
... can be applied to new diagnostic technologies and targeted
treatments to help the cancer patients. The V Foundation-AACR Grants in Translational Cancer Research offer awards to top doctors and scientists at National Cancer Institute (NCI)-designated cancer centers, prominent universities and freestanding res...
Surprise! Cells have second source of phosphate
...sphate that seems to work with as many proteins as targeted
by ATP, but in a completely different way. "There are already drugs that affect particular roles of ATP to treat cancer and other conditions, so we envision drugs that increase or decrease specific activities of this new source of phosphate could be...
Kinder, gentler procedure gives superior results for stem cell transplants
...col's effectiveness. She will also conduct studies targeted
at sickle cell anemia and chronic myelogenous leukemia to explore the potential for successful transplants in children with these disorders....
Study suggests Akt3 protein is key to melanoma's resistance to chemotherapy
... melanoma," Robertson said. "Ultimately, therapies targeted
against Akt3 could be used with traditional chemotherapy to give those with melanoma more effective therapeutic options to fight the disease." This research was supported by the American Cancer Society and The Foreman Foundation for Melanoma Research...
Broad-based vaccination of wild mice could help reduce lyme disease risk in humans
... well, including plague and West Nile virus." "The targeted
vaccination of wildlife carriers could offer more ...d senior author on the paper. "When the vaccine is targeted
to humans, only those who experienced a satisfactory immune response to the vaccine are protected; h...
Fred Hutchinson receives $9.7 million to lead early detection consortium
...virtually 100 percent of the time with surgery and targeted
radiotherapy," she said. "Once it has spread, it requires chemotherapy and becomes much harder to treat successfully." For example, solid tumors can be cured 90 percent of the time if they're detected and treated early, whereas cure rates for late-st...
Breast cancer may be 'uniquely sensitive' to inhibitors of PI3K pathway
...these intersecting circles that can be effectively targeted
with drugs." Only one PI3K pathway inhibitor is in use to date, but others are increasingly being developed and tested, says Mills, who is discussing the importance of this pathway at the annual San Antonio Breast Cancer Symposium meeting. "At l...
Screening for genital herpes should be targeted
...matic people with genital herpes infection through targeted
screening of high-risk groups may prevent disease transmission. However, widespread screening of pregnant women is unlikely to reduce the occurrence of herpes in newborns, according to an article in the January 1 issue of Clinical Infectious Diseases...
Day-long drivers at risk of cardiovascular problems as a result of traffic pollution
...ects, would require a larger number of subjects or targeted
toxicological studies". Extended inhalation of motor vehicle-related air pollution is known to increase daily deaths and hospitalization for cardiovascular diseases in the US and throughout the world estimates put the death toll at 800,000 per year ...
Novel p53 gene-based therapy boosts immune system and reduces tumor size
... was delivering was actually being replaced in the targeted
tumors, and that the treatment produced beneficial and possibly sustained local immune responses in the patients tested. "We have nice evidence of a double-acting mechanism of gene therapy, something that has not been seen before in patients treated...
Scientists stalk PPAR-gamma, find novel cancer connection
...ation, they hope the discovery will lead to a new, targeted
therapy for myeloma patients. "To our knowledge,...xperienced some success with two new, biologically targeted
therapies: thalidomide, which was given decades ago to women for morning sickness, and the proteosom...
Scientists align billion-year-old protein with embryonic heart defects
... perhaps a way to replace the faulty genes through targeted
therapy. Scientists studying a vital protein called Serum Response Factor (SRF) in mice have learned new and unexpected facts about SRF's role in early cardiovascular development, and how a defect in this gene may be an underlying cause i...
Protein 'key' could aid search for cancer drugs
...l Structure. It could aid drug makers in designing targeted
therapies that block cancer cells from multiplying... If drug makers can replicate p21's strategy in targeted
cancer-fighting compounds, they could attack cancer cells' ability to reproduce at the most basic le...
Novel drugs help solve Gleevec resistance
SAN DIEGO - Two different novel targeted
therapies can produce strong responses in patients... the second study, which found that the novel oral targeted
therapy, AMN107, can produce responses not only in advanced and Gleevec-resistant CML patients, but ...
Farnesyl transferase inhibitor can help patients at high-risk for developing AML
... the American Society of Hematology (ASH). An oral targeted
therapy gentle enough to be used by patients in their 70s or 80s is showing benefit in treating high-risk myelodysplastic syndrome (MDS), a pre-leukemic disorder that can progress to acute myelogenous leukemia (AML), according to a study presented at...
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