The Lancet Neurology November press release
...oncerns raised by the PCHAG letter. Secretases as targets for the treatment of Alzheimer's disease: the pros...ecretases". These enzymes are possible therapeutic targets to prevent or slow the onset of Alzheimer's disease. A review ( http://neurology.thelancet.com/journ...New compound holds promise for lupus and related diseases
...ake antibodies), the researchers found that Bz-423 targets a protein inside the cells' mitochondria. To test the effectiveness of Bz-423, Glick and his team then gave the compound to mice with lupus. At the end of the treatment period, 60% of untreated mice had lupus-related kidney disease, compared to 16% o...Children's Hospital Boston releases results at the American Academy of Pediatrics Annual Meeting
... of their day in school, and schools are potential targets of terrorist attacks, local school districts must begin contingency planning for terrorist events. The biodefense team at Children's Hospital is taking the lead nationally in creating protocols for treating large numbers of pediatric victims of a bi...Children in deprived areas three times more likely to be hit by a car
...plans should include pedestrian casualty reduction targets and a speed management strategy. In spite of the importance of traffic speed to the number and severity of road casualties, only one in three local transport plans presently include a clear speed management policy. Home zones in Britain should rap...VHA to measure impact of Bridge barcode patient safety system
... patient occur at the bedside, which is why Bridge targets this segment of the patient encounter for intervention. Published studies also show that BPOC technologies like MedPoint--which help nurses verify they are giving the right patient the right medication and dosage via the right route of administration...Prostate cancer program at UCLAs Jonsson Cancer Center designated a site of research excellence
...d. Researchers will seek to identify new molecular targets for therapies attempting to fix whats broken in the prostate cancer cell and investigate nutritional strategies to prevent the disease and impede tumor growth. We believe nutrition will play a critical role in the future in preventing prostate canc...Calcium-blocker drug slows artery clogging better than beta blocker
...as effective at slowing atherosclerosis. The drug targets dangerous fats that accumulate in the arterial wall and binds with vascular cells. "So it may be more powerful than other calcium antagonists," he says....$4.5 million awarded to create community drug abuse prevention trials network
...of Drug Use Risk. This multi-site prevention study targets parenting practices in early childhood to reduce later risks of substance abuse. Thomas J. Dishion is the principal investigator. The University of Alabama, Tuscaloosa, Alabama; Field Trial of Effects of the Coping Power Program. This field trial w...NIDA initiative designed to make substance abuse treatment more 'community friendly'
...n-to-be-effective family therapy intervention that targets substance abuse and other HIV risk behaviors in adolescents. Howard A. Liddle is the principal investigator. University of Pennyslvania, Philadelphia, Pennsylvania; Community-Friendly Manual Guided Drug Counseling. This project will focus on creati...New treatment strategy for Crohn's disease shows early promise
...t and traditional Crohn's therapies is that GM-CSF targets the innate immune response -- the body's built-in defense against infectious organisms. Most current Crohn's disease treatments interfere with what's called acquired immunity, which develops over time as the body encounters new infections. Generally,...New HIV vaccine holds promise of global effectiveness
... milestone in our search for a single vaccine that targets U.S. subtypes of HIV as well as clades causing the global epidemic," he adds. "This trial begins a process that we hope will culminate in a globally effective HIV vaccine," says Gary Nabel, M.D., Ph.D., who heads the VRC. "The first step is to devel...Imatinib shows early promise against Ewings sarcoma
...these results, the identification of the target or targets of imatinib that lead to cytotoxicity in Ewing's sarcoma may allow the design of related compounds with increased specificity to induce death of Ewing's sarcoma cells." In an accompanying editorial, Brian Druker, M.D., of the Oregon Health and Sci...Report card finds older Americans fail 6 of 10 goals for improving healthy aging
...But the good news is that the nation met important targets for smoking, colorectal screening, mammograms, and...among the least healthy states. All states missed targets for physical activity, nutrition, and weight. The only goal met by all states was for mammogram scr...Newly approved psoriasis drug invented and tested at Univ. of Michigan
...iting, says Ellis. "This is a unique approach that targets a specific cell that drives the over-responsive immune system in psoriasis," he comments. Only in recent years have Cooper and others pieced together enough information about the intricacies of molecular immunology to give the insight needed to desi...Schools culture of testing and targets squeezes support for 'at risk' youngsters
The current competitive culture of standards, targets and formal curriculum makes it hard for schools to be inclusive and support children with the greatest social and learning needs, according to new research funded by the ESRC. And Government initiatives to avoid children being excluded from primary s...Morphine-like painkiller appears to be less addictive
... the blood- brain barrier and reach their specific targets in the brain. These drugs may hold promise for problems related to memory, attention and even depression, he says. These glycosylated neuropeptides, as they are called, have two main advantages. First, they are easily degraded into amino acids and su...Blood test could detect heart attack early
...k progresses and may help identify new therapeutic targets for improving its treatment and outcome, Stanton says.......cific monoclonal antibodies to attack two separate targets on a single cancer cell. Most recently, the Fox C...ase their ability to kill the targeted cells. "Our targets are members of the epidermal growth factor receptor family, a powerful group of signaling proteins t...UIC researchers pinpoint genes involved in cancer growth
... only -- not healthy cells -- making them possible targets for new drugs that could halt the spread of diseas...lems in specific organs. "Obviously, the best drug targets would be genes that are needed only by cancer cells," Roninson said. One of the genes the UIC resear...Is there an alternative to expensive testing for HIV diagnosis and AIDS management?
...ients. It is an important test since the HIV virus targets and destroys the CD4 cells; patients with low numbers of CD4 cells are sicker, paving the way for opportunistic infections that will affect patient outcome. CD4 cell test results also help indicate how a patient is responding to medications/therapy. ...