Imagining movement of affected limbs aids stroke rehabilitation
...ical Medicine and Rehabilitation. The intervention targets the cognitive level of action processing, while its effects may be realized in overt behavioral performance, said Stevens, research assistant professor of physical medicine and rehabilitation at the Feinberg School. "Actions generated using motor im...HIVs assault on immune system explored at UCSF/Gladstone center for AIDS research symposium
...ge. "Dr. Koup will explain how HIV preferentially targets the HIV specific T-cells that are needed to fight HIV. Dr. Moore will discuss his work on the development of entry inhibitors, which are promising potential anti-HIV drugs and/or microbicides," said Greene. The symposium will begin at 9:30 am Wednes...Scientist gets award for sending people to sleep
...stigations of related proteins which were possible targets for anaesthetic drugs. His basic research has directly resulted in clinical advances in patients ranging from those with chronic pain to those requiring artificial ventilation in the intensive care setting. In 1999, Professor Maze became the Sir Iva...More than $34 Million in SPORE Grants
...ion pancreatic SPORE will focus on identifying new targets for novel therapies and will investigate: development of novel gene therapy to specifically inhibit an important activating protein in pancreatic cancer, NF-kappaB, in hopes of leading to a direct therapeutic application for patients role of COX......ly related to the EGF receptor. Gleevec TM , which targets an intracellular protein which sends signals similar to the EGF receptor, has completely changed the way chronic myeloid leukemia (CML) is treated and it has also shown to work in rare gastrointestinal stromal tumors (GIST). Iressa was the third such...US women endure twice the surgical biopsies as British for same cancer detection rate
...K, the National Health Service has set and reached targets that emphasize high rates of cancer detection and low recall rates. "We attribute success in the UK to their centralized program of continuous quality improvement," said Smith-Bindman. In the US, although facilities and radiologists must comply with ...New drug for non-small cell lung cancer shows efficacy
...ct theperson." Gefinitib is a "designer" drug that targets and blocks an enzyme calledtyrosine kinase, part of the epidermal growth factor receptor. Found onthe cell surface, the epidermal growth factor receptor is over-expressedin many non-small cell lung cancers. When the epidermal growth factorresponse is...Mayo Clinic researchers discover how key cancer protein works
...ng the interactions between BRCT domains and their targets will help researchers make the next move: to devise drug interventions that exploit phosphorylation bonds between key proteins. In this way, they could therapeutically regulate the cell cycle....Radically new anti-rejection drug shown to offer safe control of immune system in Stanford study
...cine researchers have shown. The drug specifically targets immune cells that lead to rejection, causing minimal side effects in animal studies. The drug also shows promise as a therapy for quieting the overactive immune system in patients with autoimmune diseases. "We can say that it does as well if not bett...Scientists identify novel enzyme with key role in leukemia protein's normal function
...ts say that enzymes such as Taspase1 can make good targets for cancer drugs and they can be inhibited with oral, relatively non-toxic compounds. Thus, a drug that blocks Taspase1 might shut down the runaway proliferation of blood cells that causes the leukemia - and might work in other cancers as well. "We'd...Comprehensive gene profiles hold promise for improving outcome of pediatric leukemia
...se genetic fingerprints might help us identify new targets in leukemic cells that could lead to the development of more effective therapies."...Yerkes researchers discover natural brain chemical reduces effects of cocaine
...ggest CART peptide receptors in the brain could be targets for developing medications to treat cocaine abuse. For their study, Dr. Jaworski, a post-doctoral fellow, and Dr. Kuhar, chief of the Neuroscience Division at Yerkes and a Georgia Research Alliance Eminent Scholar, infused CART peptide into the nucle...Brain signals from the paralyzed or injured captured by computer
...has nevertheless learned to use the robot to reach targets held by the investigator. Jonathan Wolpaw's laboratory at the Wadsworth Center of the New York State Department of Health is finding that a non-invasive BCI, using EEG activity recorded from the scalp, can provide rapid multidimensional control of a ...Drug proven to benefit heart attack victims vastly underused
...fering from acute ST-segment elevation MI, CRUSADE targets a different, but just as important, group of high-risk heart patients. CRUSADE patients will typically arrive at emergency rooms with chest pain (angina), but often will not have telltale signs of an MI on the initial electrocardiogram and may only b...Newer formulation of heparin improves outcomes for suspected heart attack patients
...fering from acute ST-segment elevation MI, CRUSADE targets a different, but just as important, group of high-risk heart patients. CRUSADE patients will typically arrive at emergency rooms with chest pain (angina), but often will not have telltale signs of an MI on the initial electrocardiogram and may only b...Jefferson scientists use gene therapy to restore function of damaged heart cells in laboratory
...s to show efficacy of ARKct and the enzyme ARK1 as targets for heart failure. "This study is the last proof of concept," he adds, noting that years of previous work in various animal models enabled the research team to reach this point. "Now we are dealing with human cells from failing human hearts." Furth...JCI Table of Contents, November 14, 2003
...ersity Medical Center discusses the potential cell targets for anti-CD154 and how CD154 acts to reduce SLE disease. TITLE: Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions AUTHOR CONTACT: Peter E. Lipsky National Institutes of Health, Beth...Novel delivery system devised for toxoplasmosis treatment
...ystem, McLeod and colleagues searched for new drug targets within T. gondii and related parasites from the ap...enzymes to live and animals don't, they make ideal targets for treatment with minimal toxicity. One such target is enoyl reductase, an enzyme discovered by McL...Experimental drugs show promise in halting brain tumors
...h another compound called RAD001. AEE788 primarily targets epidermal growth factor receptor (EGFR) and secondarily targets the VEGF receptor. RAD001 targets a different protein in cancer cells called mTOR. This protein is e...Yerkes researchers discover natural brain chemical reduces effects of cocaine
...ggest CART peptide receptors in the brain could be targets for developing medications to treat cocaine abuse. For their study, Dr. Jaworski, a post-doctoral fellow, and Dr. Kuhar, chief of the Neuroscience Division at Yerkes and a Georgia Research Alliance Eminent Scholar, infused CART peptide into the nucle...