A shallow hip socket predicts osteoarthritis of the hip
...bular dysplasia in the onset of hip OA, a research team in the Netherlands conducted a long-term study on ...d by the Dutch Arthritis Association, the research team drew its subjects from The Rotterdam Study, a comprehensive investigation of the incidence of, and r...The impact of cruciate ligament rupture on osteoarthritis of the knee
...own knee injuries. Recently, a team of researchers set out to investigate the prevalence of anterior and posterior cruciate ligament tears among middle-aged and elderly patients with symptomatic OA, as well as the effect of such tears on disease progression and pain. Their findings, p...Mayo Clinic develops first genomic-based test to predict stroke from ruptured brain aneurysm
...orting this hypothesis. The Mayo Clinic research team had previously done extensive work with a molecule...tions in ruptured brain aneurysms, the Mayo Clinic team screened the genetic variants of 49 patients who had unruptured brain aneurysms, and compared them w...Immersion in virtual world alleviates pain from injury
...d alone. To measure the intensity of the pain, the team used the Faces Scale, which attributes a score from 0 to 10, wherein 10 represents maximum pain, to a facial manifestation of pain. For younger children they used 5 different faces representing no pain to very bad pain. The researchers also interview...Potential treatment for Fragile X Syndrome demonstrated in fruit fly model
...n as antagonists, that block mGluR's activity, the team tested to see if the drugs could rescue any of the observed behavioral and memory defects observed in the fly model. "What we found was very striking," says Jongens. They found that the drug treatments restored memory-dependent courtship behavior in ...Job satisfaction? Not much for Britain's hard slog 'robot' workers
...essor Francis Green of the University of Kent. His team found no evidence to back suggestions that the dull mood of workers may be due to successive generations having ever higher expectations from their jobs and being disappointed by the realities of employment. The investigation, which also looked at o...Brain tumor with dismal prognosis in infants can be cured in older children
...of the brain that controls balance. The St. Jude team showed that, while children with ATRT under three ...ome a standard approach to ATRT therapy." Gajjar's team studied the medical records of 31 patients, 22 of whom were younger than 3 years old. All patients h...Both inherited traits and tumor mutations affect response to treatment of leukemia
...this study, the researchers suggest. The St. Jude team demonstrated that certain traits inherited from parents could reduce the effectiveness of some cancer chemotherapy. The findings therefore have the potential to improve treatment outcome by providing additional genetic clues that enable clinicians to...Fewer false alarms when mammographers have greater experience screening healthy breasts
...ing to a new study. The research was led by a UCSF team and is published in the March 2 issue of the Journal of the National Cancer Institute . Screening mammograms are the type most women get. These images are designed to discover any cancer that might be hidden in women with no breast symptoms. Women w...African-Americans receive less aggressive heart attack treatment
... Medical Association (JNMA). Bertoni's research team analyzed data from more than 660,000 patients in t...'s gender or geographic location. In addition, the team noted that rates of catheterization between Latinos/Hispanics and whites had grown more similar in r...Genetic amplification (NAAT) test detects HIV more effectively than standard tests in urban study
...tween October 2002 and January 2004. The research team used both standard antibody testing and NAAT testing to screen specimens from 2,202 people who had not previously tested positive for HIV. Sixty-six of the specimens were found to be HIV antibody positive and 2,135 were HIV antibody negative using s...Dual testing better for monitoring new cases of HIV
...roviral therapy more widely available. The Hopkins team successfully determined new cases from old by adding the Affinity/Avidity test to the current STARHS protocol, the test widely used by the United States Centers for Disease Control and Prevention. This second test measures the strength of antibody-a...Archival virus still necessitates life-long antiretroviral therapy
.... However, recently published data by the Hopkins team on blips in HIV levels concludes that this archival virus is not mutating to become drug-resistant....LRRK2 gene mutation causes Parkinson's disease in several families
...ts at Mayo Clinic in Jacksonville, Fla., leading a team of researchers in the United States and Europe, have discovered that a novel mutation in the recently identified LRRK2 gene causes parkinsonism in several North American and European families. Their findings will be reported in the April edition of t...New imaging technologies can enhance orthopaedic outcomes
...ery offers one of the largest and most experienced team of musculoskeletal radiologists in the world....Major review of subway systems suggests potential for significant health and safety hazards
... Dr. Gershon's paper reviews noise level data her team recently collected which indicate that there is a potential for concern. They found that current levels are as high as they were in the 1970s, and in some cases, the levels were higher than recommended by health experts. She notes, "While many ride...Adverse drug events in nursing homes are far more common than previously identified
... prevent these kinds of events." Dr. Gurwitz and a team of physicians and pharmacists reviewed patient rec...emia., and kidney problems. In 2000, Dr. Gurwitz's team published a similar study which identified adverse drug events in community-based nursing homes. The...Plant derivative attacks the roots of leukemia
...igued by the plant's anti-tumor activities, the UR team analyzed how a concentrated form of parthenolide would act on the most primitive types of acute myelogenous leukemia cells, chronic myelogenous leukemia cells and normal cells. In laboratory experiments, they also compared how human leukemia stem cel...CK2 protein sustains colon cancer cells by sabotaging ability to commit suicide
...t have some features of muscle cells. The St. Jude team showed that CK2 exerts its anti-apoptosis effect w...urnal Clinical Cancer Research. In that study, the team reported similar findings in rhabdomyosarcoma cells. In the current study using human colon carcino...Protein that promotes survival of stem cells might be key to poor leukemia prognosis
...T lymphocytes. In the Science study, Opferman's team genetically modified mice so that the gene for Mcl...as needed to maintain these cell populations. The team also demonstrated that BM cells lacking Mcl-1 did not multiply when removed from mice and cultured i...