DNA Imaging to Design Better Drugs
...t synthesizes a potential drug, we canvery quickly tell them if it binds to DNA, how tightly it binds, and themode by which it binds," he added. One of the major advantages of the new assay is it shows researchershow drugs affect single DNA molecules, said Dr. Lawrence Bottomley, aGeorgia Tech chemistry ...Postmature Infants Not As Easily Calmed As Other Newborns
...ymptoms of Clifford's syndrome. "It's difficult to tell whetherthe fetus is suffering from postmaturity until it's born," shesaid. Research has shown that 1-year-olds born with Clifford's syndromeexhibit a lower attention span than normal babies, are morerestless and score lower on some tests. Another stu...Duke Study Uses Tiny Temperature Changes To Probe Water-Exclusion At Protein Binding Sites
...in's structure and the ligand'sstructure they will tell you where the ligand might bind," Toone added. But scientists' problem is they have not yet uncovered all of nature'stricks for making the binding sites suitably "sticky," Toone said.So, surprisingly, instead of pinpointing the one actual bindi......nts have to teach these things just as they should tell their children about the harmful effects of drugs ...essage that it is OK to have sex. We can't seem to tell our kids directly, 'I don't want you to have sex yet,' and why." Teenagers, she says aren't smart a...Ultrasound Helps Pediatric Heart Surgeons After Open Heart Surgery
... in children. This non-invasive method can tell the cardiovascular surgeon andanesthesiologists ho...nd ofmonitoring is if you see lots of air, you can tell the surgeon he needs to domore deairing -- it is a feedback system," Rodriguez said. By mo...Cancer Protection Compound Abundant In Broccoli Sprouts
...iable in broccoli samples, and there was no way to tell which broccoli plantshad the mostwithout sophisticated chemical analysis. "Even if that were possible, people would still have to eat unreasonablylarge quantitiesof broccoli to get any significant promotion of Phase 2 enzymes," Talalay says. ...Targon And Duke Cancer Center Sign $3.75 Million Agreement To Produce Advanced Anti-Cancer Drugs
...r to judge, and we need new biochemical tests that tell us if the drug has successfully disrupted the intended pathway in the cancer cell, while not interfering with similar pathways in healthy cells. Targon's support will enable us to develop such necessaryclinical measures." The Duke Comprehens...Hollywood Increases Film Portrayals Of People With Disabilities
...all 'disability movies,'but most film critics will tell you there is very little reality basis in thefilm," said Safran, who teaches a course on disabilities in the media. "But manydon't have any basis in reality. Look at 'Forrest Gump.' He's what we call a'Supercrip.' People love to see these kinds of mo..."Powerful New Tool" For AIDS Is Reported In Science
... about the causes of immune deficiency. How can we tell if an individual cell is an old one or a newly fo...shot of a stormy sky or a baseball pitcher doesn't tell you what you really want to know - how fast are the rain clouds moving and how hard does the pitcher...X-Rays: How Big A Risk To Kids? UF Researchers Seek Answers
...omefluoroscopy and several chest x-rays, could you tell me what the actualdose was?,' no one can do that right now," said Kathleen Hintenlang,assistant radiation control officer at Shands hospital at UF and one offour researchers heading the project. "If the parent asks what the riskwas, nobody can give ...Optical Technology Projects Images Directly Into The Eye
...ne another on the retina that the eye is unable to tell them apart. The RSD technique makes it possible to project realistic pictures covering a wide field of vision. A three-dimensional impression isformed by sending slightly different images to each eye and it is also possible to produce a colour image...ACS Industry Pavilion Features Chemistry's Cutting Edge
...imulationof Earth in the Arizona desert that could tell us about the fate of ourplanet -- Mon., March 30, 2:30 to 3:30 p.m. The future of the chemical industry will be addressed by a panel ofsenior managers from top U.S. chemical companies and investment firms who willdiscuss trends an...National Office Of Drug Safety Is Needed, Experts Say In JAMA
... "Without [good] data, it is impossible to tell whether serious injuriesassociated with prescription drug adverse effects are declining or whether anepidemic of drug-induced injury may be occurring," they write. They observe that the FDA has 1,400 employees working on approving newdrugs, b...Health Risk To "Cigarette Babies" Is Neglected, Duke Scientist Charges
...ally releasedin a precise sequence of signals that tell the sensitive growing brain cells howto "wire" their connections. However, nicotine stimulates the same cellreceptors as acetylcholine, at the wrong time and with inappropriate intensity,confusing the normal development process and causing the fetal ...Extreme Prematurity Brings Two-Fold Increase In Risk Of Repeating A Grade, Needing Special Education
...ime at our center, neonatologists have the data to tell parents the risk of having their kids do OK in school, not merely their risk of survival. That is powerful information." Buck noted that while prematurity is likely to result in educational problems, other factors, such as non-white race a...Anti-Depressants: Miracle Drugs Or Placebos With A Buzz?
...eceived medication (rather than a dummy pill)could tell by the side effects that they had takensomething. This result was seen in all the studies in the meta-analysis, includingthose involving drugs not considered to be anti-depressants,but which were as effective as anti-depressants in treating d...Cure Rate Soars For Some AML Patients Receiving High-Dose Drug
...those patients who will benefit. These results tell us which patients we can cure, and which ones should receive other therapy.” The finding is considered particularly strong because the study had followed patients for more than seven years after treatment; most such studies rely on...New Surgery At Cedars-Sinai Provides Hope For Epilepsy Patient Who Has Had A Lifetime Of Seizures
...feels wonderful -- and extraordinarily thankful."I tell people, if Dr. Levesque was a religion, I'd join," said Mary Kate,laughing. "He's the best." Though Mary Kate, now 33, had experienced some extended periods withoutseizures, they always seemed to return and typically with greater intensity. Theepilep...Statistician Keeps Health Researchers Ahead Of The Curve
...aps four years after HIV infection, thiscurve will tell you," he says. A native of China, Wu came to the United States in 1982 to study at UCLA, wherehe earned a bachelor's degree in mathematics. In 1990, he received a doctoratein statistics at the University of California, Berkeley. He has been a facult......rials have not been performed, it is impossible to tell whether symptoms arepart of the patient's condition or an effect of the drug." If a drug is not licensed for children, a doctor will often estimate asuitable dose by extrapolating according to body weight from the recommendedadult dose. But c...