Chemist Turns To Self-Assembly To Create New Drugs
...dless variety of potential drugs, thenplucking out the most promising candidates for further study. Miller's system shifts the burden of the most painstakingdrug-development work off the shoulders of technicians and ontotiny mo..."Powerful New Tool" For AIDS Is Reported In Science
...ed technology developed by Dr. Marc Hellerstein of the University of California at Berkeley and the University of California at San Francisco. The technology will be commercialized exclusively by Spe...Research Trial To Test New Drug For Diabetic Neuropathy
...cation of diabetes that impairs nerve function in the lower extremities and can lead to foot ulcers and...rg, MD. " Nerves conduct electrical signals to the arms and legs. When this doesn't work properly, it is called neuropathy. This drug shows great pro...Four-Year Study Shows Long-Term Effectiveness Of Proscar In Treating Enlarged Prostates
...dy involving 3,040men have shown that those taking the drug finasteride (Proscar) forenlarged prostate gl...oscar Long-Term Efficacy and Safety Study (PLESS), the longest trialof drug therapy for men with benign prostatic hyperplasia (BPH). The study part...New Math, High-Tech Imaging Solving Old Riddle: How Does The Brain Operate When We Think?
...us detailed magnetic resonance imaging pictures of the brain may addup to a betterunderstanding of the experience of thinking. The work, done in animals, offers promise for studying the brain at w...Deaths Related To Intrapartum Asphyxia - Is There A Problem With Prevention?
...l oxygen supply, in an effort to ascertain whether the causes of fetal death around the time of delivery present themselves differently during the night. Contact: John Spencer, Consultant ...Do Asthma Treatments Affect Childhood Growth?
... and weight and had normal growth rates. However, the authors identified children using high dose stero...ontemporaries, but social deprivation seemed to be the dominant influence. Contact: Mr C McCowan, Project Officer, National Asthma Campaign, Tayside Cen...Do Deaths Of Babies From Birth Asphyxia Vary Depending On When They Are Born?
...erinatal survey, 1993-5) Deaths of babies around the time of their birth, although rare, seem to be mor...this week's BMJ. The authors raise concerns about the variability of care around the time of delivery and from their study of 79 babies' deaths from birt......avior changes, but an article in theMarch issue of the journal Pediatrics shows that in most children, the drugscause no major changes in behavior or reasoning skills. Both drugs have beenprescribed to treat......irritable--a personality traitthought to be one of the stable touchstones of identity--can be shifted moretoward the easy-going side by a drug used to treat depression, University ofCalifornia San Francisco researcher...A study in the NEJM titled "The effect of nisoldipine as compared...nd non-fatal heart attacksamong individuals taking the calcium antagonist nisoldipine compared toindividuals taking enalapril, which is a member of a class...Added Benefit Found For Aspirin Use In Patients With Vessel Disease
...atty deposits clogging theblood vessels -- occurs, the result can be damage to the endothelium that linesthe inside of the vessel. When there is damage to the lining -- known asendoth...Snipping Inflammation In The Bud; New Agents May Provide Relief
MADISON - Trying a new approach to controlling the process of inflammation,scientists have forged a n...ffer a newstrategy for treating pain, swelling and the other hallmarks of injury orillness. Writing this week (March 5) in the scientific journal Nature, U...Airport Noise Can Seriously Affect The Health And Psychological Well-Being OfChildren
... have lifelong effects. "This study is probably the most definitive proof that noise causes stress and...ell's College of Human Ecology. This is, he says, the firstlongitudinal study of noise and human beings to look at the same group ofindividuals before and...Could Cardiovascular Drugs Be Linked To Suicide?
...g et al investigated possible associations between the use of cardiovascular drugs and suicide and the results of this study are published in this week's BMJ. The authors found a significant correlation...Setting Prescribing Budgets In General Practice
... prescribing is appropriate and cost effective. To the contrary Greenhalgh argues that Majeed and Head fail to take into account the reality of the variability of prescribing costs between practices, even when local factors are accou...Hospitals Discourage Consumer Questioning Of Bills, Study Suggests
...e inthis month's edition of a journal published by the Institute for OperationsResearch and the Management Sciences (INFORMS). The study, part of a broader analysis of what scholars call anticipa...Study Finds Aspirin Does Not Prevent High-Risk Cases Of Preeclampsia
... who are at high risk for thedisease, according to the largest, most comprehensive study of its kind. ...warning,causing high blood pressure and protein in the urine. In turn, preeclampsiamay progress to eclampsia--hypertension and generalized convulsions--w...X-ray Microscope Designed To Study Jet Engine Components Now Probes Tooth Dentin
...loped at Lawrence Livermore NationalLaboratory for the Department of Energy, researchers at the UC San FranciscoSchool of Dentistry are probing the intricate structure of dentin, the porousmateria...... to help design moreeffective pharmaceuticals with the help of computers. "Stronger chemical binding gen...ously testing each one," Jorgensen said. "Part of the hope withrational drug design and computers is to narrow the search, to pinpointthe modifications th...