UI Study Yields Encouraging Results For New Breast Cancer Treatment
...ology. "Within the high-dose chemotherapy range, therapies of lower intensity do notappear effective," Gingrich said. "We now need to examine whether an approachsuch as ours, when tested in a randomized, comparative fashion, will bebeneficial. We certainly think it will."......rate the potential benefits of combining these two therapies in the treatment of heart attack. The study showed that 72 percent of heart-attack patients who received abciximab plus half the standard dose of the clot-buster alteplase (tissue plasminogen activator, or t-PA) achieved optimal blood flow in their...Wanted: Holistic approach to cancer treatment
... the dozens of complementary and alternativecancer therapies that are in wide use by patients. Conventional therapies likeradiation and chemotherapy offer documented levels of effectiveness, but withfairly high toxicit......lentlessly progressive deterioration on palliative therapies to the hope of extended survival," said Dr. Rai, who isalso one of the trial's principal investigators and an internationally recognized expert inCLL. ILEX and LeukoSite are developing CAMPATH through a joint venture that was established in May 1997....NIH study to evaluate role of MRI in emergency diagnosis of heart attack & stroke
...ttack will be treated with currentstate-of-the-art therapies such as a clot-busting drug or balloon angioplasty. MRI evaluation of these patients will occur after stabilization. For patients without a definite explanation for their chest pain,scientists hope to use the high quality image of MRI to rapidly iden...Novel drug therapy tackles third 'pathway' causing congestive heart failure
...rdiology at the Houston VA MedicalCenter. New drug therapies to treat heart failure are needed because currentmedications, while alleviating symptoms and prolonging life, can slow, but don'talways halt the progression of the disease, says Mann. He adds that heartfailure is the only form of heart disease that ...Mayo clinic researchers explore new methods to detect Parkinson's disease in at-risk individuals
...ways to discoverwho is most at risk and to develop therapies that can delay or prevent the onsetof this disease," says Dr. Maraganore. "The results of our study are veryencouraging, but clearly there needs to be continuing research and developmentin this area."...Cholesterol-lowering drugs provide double protection against heart disease
... eight to 15 months aftermedication and/or dietary therapies were given. Myocardial blood flow at rest as measured by PET was similar in thehigh-cholesterol patients and those with normal cholesterol levels, both at thebeginning and end of the study. However, when people in the two groups weregiven the dilatin...Jefferson scientist begins clinical trial to study promising Parkinson's disease drug
...ll supply the drug for the study. "Current therapies for Parkinson's disease treat only the symptoms anddo little to address the underlying disease process," Dr. Schneider explains."Despite the fact that you can alleviate some symptoms for a time, the diseaseprocess continues. It's a progressive neurod...Obesity drugs not a quick fix for achieving weight loss
...y aspects of obesity arepoorly understood and that therapies often are unsuccessful in the long term. Changes in lifestyle are the cornerstone of obesity therapy. Eating less andincreasing physical activity usually help obese patients lose weight, and losingas little as 5 percent to 10 percent of total body we......he mostadvanced treatment options -- such as novel therapies for pituitary tumors,growth hormone replacement for adults, pituitary function testing, and more. Inaddition, because Cedars-Sinai oversees more pituitary disease clinical trialsthan almost any other facility in the country, patients will have unpara...Experimental peptides prevent diabetes and halt its progression
...ngs may be of importance in designing prophylactic therapies forhumans included in diabetes prevention trials, since such individuals arecurrently selected on the basis of having developed significant levels of betacell autoimmunity." Co-authors of the report are UNC postdoctoral researcher Dr. Bo Wang, and Dr...UCSF Cancer Center joins elite group of National Cancer Institute-designated centers
... thetranslation of laboratory discoveries into new therapies for improved patientcare." After the initial three-year funding period, the UCSF Cancer Center is eligiblefor a five-year NCI renewal grant. Typically, this grant amounts to 20 percentof the total NCI funding an institution receives to support peer-r...First NIH clinical trial for interstitial cystitis begins
...oal is to be able to recommend to physicians those therapies mostlikely to relieve symptoms in subgroups of patients." The cause of interstitialcystitis is unknown and no one therapy works effectively in a large number ofpatients. Often mistaken for a bladder infection, IC may elude diagnosis foryears. Clini...Study suggests potential new approach to glaucoma therapy
...." For the last century, most medical and surgical therapies for glaucoma haveattempted to lower pressure in th...sion in those patients who don'trespond to current therapies and also could be used along with drugs that lowerintraocular pressure. "The emerging concept of usi...Decline in awareness and treatment of high blood pressure could pose a serious public health threat
...blic a factor? Is the cost of high blood pressure therapies an importantfactor in these findings? And finally, what is the effect of managed care? "The answers to these questions are not readily apparent from our study,"Meissner says. "But this is an important subject for future research. Understanding the ...New studies of a liquid of life -- Lung surfactant
... Of the two FDA-approved surfactant replacement therapies currently inuse, one is a purely synthetic formulation, called Exosurf. It contains about 80percent dipalmitoylphosphatidylcholine, or DPPC, combined with hexadecanol andtyloxapol, explained Zasadzinski. DPPC is also the main component of naturalhu...UI researchers discover that aggressive cancer cells may make their own blood vessels
...owth and spread can continue even whenconventional therapies are combined with experimental chemotherapies that mayblock angiogenesis in animal models and in humans. "The vascular channels form between tightly packed groups of aggressive cells;and basic tissue processes, such as perfusion, can continue to oper...Nortran Pharmaceuticals Inc. and Hoechst Marion Roussel announce collaborativeagreement
.... Itsmajor products are among the world's leading therapies for allergic, metabolicand central nervous system disorders and as well as cardiovascular andinfectious diseases. Based in Frankfurt, Germany, Hoechst Marion Roussel is thepharmaceutical company of Hoechst AG, an international company that focuses o......breast cancer treatment such as HER2/neu proteins, therapies canbe tailored to fit the needs of each individual patient. Currently, a generalrecipe of surgery, radiation and chemotherapy is considered for everyone withearly stage breast cancer. "Once you get this information, you get a better idea of the natur...