Duke Study Suggests New Class Of Drugs Could Bypass Leptin Loop
...dying the leptin loop, Duke researchers discovered they could applya hormone -- a synthetic form of noradrenaline -- directly onto the surface of fat cells,essentially bypassing the leptin circuit. Receptors on the fat cell's surface, called B3 adrenergicreceptors, receive the hormone's signal and transm...AIDS Treatments Seek To Eradicate Virus, Restore Immunity
... depletedimmune system unable to fight infections, they also are vulnerable to secondarydiseases such as c...veloplymphoma, a cancer of the lymph tissue, which they frequently do not survive. The team of Duke physicians and researchers is ready to take an ...Study Says Machine Sensors Applicable To Human Ills
...icians as soon as a patient becomesat risk so that they will be able to intervene in "the golden 20 minutes"when drug therapy can be most effective. Penn State's ARL, a Navy-oriented facility, was chosen to lead the PredictiveDiagnostics Team because of its success in transferring military technologyto ...DNA Imaging to Design Better Drugs
Designing drugs and knowing exactly how they work may have justgotten easier, thanks to researc...us academic andindustrial labs across the country, they have not been widely used inpharmacological applications. Now these microscopes can play a vitalrole...Digital Speech Analysis Tests Sobriety
...enough for a comprehensivestudy, but Cummings said they form a sufficient database to makegeneralizations. "If you see consistently the same trend between sober andintoxicated speech for four different speakers, that's actually a lot,"she said. Also, Cummings plans to continue her research on the other ...Chemists Develop Probe To Detect Changes In Imaging Agents Inside Body
...determine what happens to medical imagingagents as they travel through the body and accumulate insidevario...udents decided to try to develop asensor to see if they could monitor what happens to an imagingagent after it enters the body. "We just happened to be in a...Testosterone May Affect Learning Skills; May Be Put In Tablet Form
...stosterone treatment. When receiving testosterone, they had improved visual and spatial skills and a bette...llowed the men to perform as well sexually as when they received testosterone injections but without prolonged exposure to a high hormone level caused by in...Emory Doctors Discuss "Killing Heat" In This Week's NEJM
... poor citizens during heat waves are "not enough," they say. "Unfortunately, the most well-intentioned ...ditioners have been turned off by victims who felt they could not afford the utility bill. Homes can become super-heated if the windows are nailed shut to ...Maternal Exposure To Crack Cocaine Produces Stressed Newborns
...ore muscle tension, and were harder to movebecause they were stiff." Some cocaine-exposed infants were als..., vulnerable babies. With the properchild rearing, they will do fine. If the resources are available, it's possibleto intervene with drug-abusing moms early...Discovery Hints At Multitude Of New Targets For Drugs
...locking itsaction. However, surprisingly, they discovered a new class of compounds that behaveddi...btype. But if there was only one kind of receptor, they were stuck. "But now, our laboratory and others are showing that different compoundsacting ...Scientists Produce New Anti-Malarial Compound
...nism to kill the parasite that causes malaria, but they aremuch less expensive and easier to produce than ...s called Anopheles,which pick up the parasite when they bite an infected person. Theinsects then transmit infected blood to other people.Anopheles mosquitos...Raising The Retirement Age In The United States Could Save Billions In Social Security Payments
...rity and disability insurancepayments. On average, they said, increasing the normal retirement age to70 co...ge increase in disability paymentsfor workers once they pass age 65, but that has not been the case, the researcherssaid. They noted in their report there ...A Surgical Semiconductor Laser With More Precision And Power
...ore durable and more user-friendly, he says, since they have no gastanks to replace or mirrors to care for...es only five watts to produce thesame power. Since they can be mass-produced, semiconductor lasers usually cost only a few thousand dollars, compared totens......ber of CD4+ T cells in the 17 HIV-infected infants they characterized with a thymic-defect profile averaged 536 cells per mm3 compared with 2,139 cells per mm3 in 42 HIV-infected infants without the profile and with 3,142 cells per mm3 in 168 control infants who were exposed to, though not infected with, ...Stents Work Well, But Are Costly: Will Hospitals Continue To Use Them?
... heart arteries may go bust when hospitals realize they are losingtheir profit margins, a researcher has c...ollar is spent, and 'stenting' may become a luxury they can't afford." Cardiologists insert the mesh-like structures to keep arteries openafter clogs have...KUMC Researchers Announce Breakthrough Method For Predicting Epileptic Seizures
...at the University of Kansas Medical Center believe they have unlocked the complicated secret of predicting when a patient with epilepsy is about to have a seizure. In recent studies of 125 seizures monitored and recorded at KU Medical Center, the technique has predicted seizures by up to three minute...It Matters Where, In America, You Suffer A Heart Attack
...talization of these patients during 1990-1993, and they tracked what happened to them up to one year later...edures and hospital stays varied widely, more than they expected. "The contrasts were quite striking, including some large differences in efficiency that we...Postmature Infants Not As Easily Calmed As Other Newborns
... behavior ofinfants who remain in the uterus after they should have beenborn. The babies generally do not ...l, crying babies, and keeping them calm even after they nolonger taste the solution. But if the same sugar solution isgiven to an infant born with Clifford'...Premature Birth Sometimes Can Adversely Affect Infant's Ties To Mother
... age group rather thanwith other premature babies; they see their child as behind developmentally. "There...me of these babies were the size of your hand when they were born,and they had been hooked up to machinery to keep them alive. Yet we latersaw them running ......hen the medication is discontinued. Consequently, they have largely agreed that for weight reduction drug...ust how much weight people could expect to lose if they took Redux or a similar drug for a long time, Levitsky analyzed the studies from all the articles pu...