Tighter Chemical Binding = Better Meds
...es in tweaking chemical compounds to tighten their ties to targetproteins. Using sophisticated computer graphics and his knowledge of thethree-dimensional structure of protein molecules, Jorgensen consults withmajor pharmaceutical firms regarding new methods of rational drug design. "Historically, drug ...Scientists Report Cancer Fighting Drug As Possible Treatment For Multiple Sclerosis
...ic field of modern cellbiology. The university has ties to 19 Nobel laureates, including the president,Torsten N. Wiesel, M.D., who received the prize in 1981. The university recentlycreated six centers to foster collaborations among scientists to pursueinvestigations of Alzheimer's disease, of biochemist...Neurotransmission Machinery Visualized For The First Time
...vantage of the fusion machinery by attacking these ties betweenneurotransmitter-filled vesicles and the neuron's membrane, effectively cuttingthe winch cable and causing neurological symptoms." Advances in knowledge about the protein complex's structure could be ofpotential use in designing new medication...Study examines faith healing in a cell phone age
...0 live inother parts of the country and keep close ties to Navajoland. The reservation is located in the "four corners" region joiningNew Mexico, Arizona, Utah, and Colorado and aligns with the compass of four sacred mountains that correspond to thecardinal directions, an important orientation in Navajo c...Injured elite athletes need team support
Maintaining ties with teammates will help injured elite athletes recover morequickly, says U of T professor Lynda Mainwaring. Elite athletes who suffer from severe injuries feel isolated from team members,says Mainwaring of the Faculty of Physical Education and Healt......st cancer. The grant further reinforces the strong ties between the universities that have helped to produce breakthroughs enhancing their reputations as world leaders in scientific and medical research. "The fact that Pittsburgh will become the home to one of only five such centers to be established nati...Media coverage of new drugs is often misleading
Financial ties of cited experts go undisclosed Newspaper and te...cent of news stories citing experts with financial ties to the drug being studied disclosed this potential conflict of interest. "Major scientific journals ...UNC-CH School of Social Work receives grant to prevent violence
... Families program" has been designed to strengthen ties between children's homes and their schools by boos...eynolds Foundation, in which they developed strong ties with Dr. Larry Mabe, superintendent of Chatham County Public Schools and Susan Eckblad and Randy Joh...Low dose estrogen improves bone health
...ughout the three-month study. Researchers have no ties to Bristol-Myers-Squibb, which provided the estradiol and placebos, or to Mission Pharmaceuticals, which provided the calcium citrate and vitamin D. The women tracked their estimated dietary calcium intake with food diaries and their physical activi...... do now.* Apply required disclosure of financial ties to anyone involved in researchfaculty, students, and staffand that disclosure should be both on a set periodic basis as well as in real time if their situation changes. Asks institutions to consider a higher standard for clinical research than for ...Neuroscientists searching for roots of empathy find brain regions involved in learning by imitation
...her daughter how to tie her shoelaces. The mother ties a shoelace and the child follows, trying to imitate the action. We would expect the same kind of lateralized brain activity in learning to tie shoelaces as there was in our experimental task. The second study, which involved 10 right-handed subject...Strong relationship between peasant farmers and city-dwellers in Zimbabwe
... choose to return to the countryside due to family ties and because their ancestors are buried there. Sometimes people exchange a well-paid job in the city for a poorly paid position in the village where they were born. The unequal distribution of land between black and white Zimbabweans arouses a strong ...NIAID Phase III HIV vaccine trial to determine correlates of protection will not proceed
...nt and testing and their established collaborative ties in many parts of the world will enhance NIAIDs expanding international efforts. In turn, USAMRMC programs will benefit from NIAIDs vast HIV/AIDS pre-clinical research program, which is integrated into NIAIDs comprehensive HIV/AIDS research effort. ...Eliminating health disparities requires community involvement
...arities share common traits of establishing strong ties between health providers and the community members they serve, according to a group of studies just published. Areas in which innovative programs are having a positive effect are: infant mortality, cancer screening and management, cardiovascular dise...Input from youth is crucial in promoting adolescent health
...ing communities, building trust, and strengthening ties between academic researchers and the communities they serve....Buck researcher makes progress in fight against Huntington's Disease
...nvolved in pathogenesis, and the calpain discovery ties this knowledge together nicely," Dr. Ellerby said. "This is not the one cause for Huntington's Disease," she added. "The relationship between calpains and Huntington's disease progression will require further work." Both post-mortem disease tissue...Study on suicide reveals faith, social ties as 'protective' for older African Americans
...African Americans with strong religious and social ties were the least likely to have suicidal thoughts. "The good news is that there are protective factors in the community, and we can work to facilitate and maintain the strengths that are already there," said Cook. She said the findings may be helpfu...UW-Madison leads $26 million study on aging
...; social factors, such as support networks, family ties and social participation; psychological factors, such as personality, coping strategies and goal orientations; and health behaviors, such as substance abuse, physical activity and hormone therapy. Similar data were collected on these individuals a d...St. Jude to receive multi-million dollar grant for sickle cell program
...e St. Jude sickle cell program will develop closer ties to centers treating adult sickle cell disease, sharing research and treatment findings. Most pediatric sickle cell patients in the Mid-South will continue to receive their primary care at the St. Jude sickle cell clinic, which is located at Le Bonhe......ulation. This supports the view that strong family ties reduce the risk for suicidal behaviour, say the authors. The strongest risk factor for suicide is mental illness, and other studies have found mental illness to be slightly more common among twins than among singletons. "This should lead to a higher ...