College alcohol problems exceed previous estimates
...forcement of the legal drinking age of 21 and zero tolerance laws, increases in alcohol taxes, and wider implementation of screening and counseling programs, and comprehensive community interventions are among the strategies that can reduce college drinking and associated harm to students and others....Medically supervised drug injection facilities safer for users
...ting drug use, the most probable reason for public tolerance of supervised injecting facilities in Europe. An important step in persuading the community that supervised injecting facilities have a role to play in reducing the harms caused by injecting drug use is to encourage more realistic expectations in the...Chemists identify immune system mechanism for methamphetamine binges
...may be able to recognize methamphetamine and boost tolerance to the drug through an unusual vaccine-like mechan...immune system recognition and a consequent rise in tolerance to the drug, Janda and his associates theorize. Tolerance refers to the capacity to have a decreased...Two years after gene therapy treatments, severe angina patients showed prolonged clinical benefit
...and citing significant improvement in the exercise tolerance time in all dose groups. The study reports reflec...age increase of almost two minutes of the exercise tolerance time in the VEGF-2 treated patients, and significant decrease in angina class in 50% of patients in ...Hyperactive kids three times as likely to be removed from their families
...The disorder challenges "not only our professional tolerance but also the way paediatric services for all community based childhood disorders are currently structured," writes Dr Mary Mather, a consultant community paediatrician. Hyperactive children are not a priority, she continues. "Yet their outcomes are p...Single-donor islet transplantation procedure shows promise for patients with type 1 diabetes
...ol (as evidenced by normal results of oral glucose tolerance testing in 4 of 5 recipients with sustained insulin independence) using significantly fewer islets," the authors write. "These findings may have implications for the ongoing transition of islet transplantation from clinical investigation to routine c...Herb used to treat diabetes works like modern-day prescription drugs, study suggests
... healthy adults participated in four separate meal tolerance tests. These meals, which were given in beverage form, were spaced three to 14 days apart. Each participant fasted for at least 10 hours before consuming the test beverage. Participants were asked to drink about two cups' worth of the chilled beverag...UCLA brain scientists crack mystery of how alcohol causes intoxication
... gene mutation in rats' brains lowers the animals' tolerance to alcohol, leading to rapid and acute intoxicatio...t the gene mutation arises naturally suggests that tolerance levels to alcohol may be genetically wired in people, too. If so, the findings could eventually he...JCI table of contents, January 20 2005
... responses to self. Just how T cells maintain this tolerance to self is not fully recognized. During T cell maturation, those cells that have a high affinity for self antigen and tissues are normally deleted before they escape the thymus. However some T cells only possess an intermediate affinity for self anti...American Thoracic Society Journal news tips for January 2005 (second issue)
...he researchers noted that there was no evidence of tolerance to the bud/form combination since results were maintained over 12 months. The research appears in the second issue for January 2005 of the American Thoracic Society's peer-reviewed American Journal of Respiratory and Critical Care Medicine . U.S.-...Weight loss strategies work in people with pre-diabetes
...ys. People with pre-diabetes have impaired glucose tolerance that doesn't quite rise to the level of a diabetes diagnosis, although the pre-diabetes condition can be "an important risk factor for the development of type 2 diabetes," Norris says. Pre-diabetes affects almost 12 million overweight people ages 45 ...New 'ITN Scholars Program' provides junior faculty opportunity to develop clinical trials expertise
... trials experience in the emerging field of immune tolerance therapies. Mohamed H. Sayegh, M.D., Professor of Medicine at Harvard Medical School and Chair of the ITN Scholars search committee, says that effectively planning clinical trials of emerging immune-based therapies requires a rare combination of s...Anti-psychotic drugs may be associated with increased risk of diabetes in schizophrenia patients
...ndergoing a frequently sampled intravenous glucose tolerance test. "Both nonobese clozapine- and olanzapine-treated groups displayed significant insulin resistance and impairment of glucose effectiveness compared with risperidone-treated subjects," the researchers found. In conclusion the authors wri...Cedars-Sinai medical tipsheet for Dec. 2004
...ct on key cells that result in the immune system's tolerance of deadly brain tumor cells. By blocking the enzyme's expression in gliomas before exposure to dendritic cells, COX-2's effects may be interrupted and a more effective immune response may be launched. Study results are published in the October 1 issu...Millions who suffer from nut and milk allergies could benefit from Stanford researcher's test
... had a more than a hundred-fold increase in peanut tolerance - from half of one peanut to 57 peanuts. Similarly, when milk-allergic dogs were fed 0.2 grams of milk two to four months after vaccination, they exhibited a 100 percent reduction in vomiting and a 60 percent reduction in diarrhea compared to t...University health study identifies undiagnosed diabetics
... "Another way to check for diabetes is the glucose tolerance test, where the patient's blood sugar levels are first measured after they have fasted. The patient then has a glucose drink and a further blood sugar level test after two hours. Someone with a normal level of blood sugar after fasting, but whose l...Abdominal fat decreases, insulin action improves when elderly take hormone
...ificantly lower insulin levels during oral glucose tolerance tests than at the start of the study. Their glucose levels remained unchanged, and these results indicate an improvement in insulin action. The degree of improvement in insulin action correlated closely to the amount of decrease in visceral fat. "Amo...New finding could make addiction treatment more effective
...ed. In chronic alcohol users, the brain develops a tolerance to the sedative effects of alcohol and there is an increase in light sleep and a decrease in restorative sleep. This may prompt alcohol users to increase their consumption to try to improve sleep. One study revealed that 44 percent to 60 percent of a...Smoking affects same 'feel good' brain chemical system as heroin
...e, the phenomena of pleasure, addiction, increased tolerance and craving from tobacco are firmly rooted in neurochemistry." Adds veteran tobacco researcher and U-M emeritus pharmacology professor Ed Domino, Ph.D., "Nicotine addiction is one of the most destructive forces in human health, and we must increase o......els of CREB phosphorylation, a measure of cellular tolerance to stress and of the ability to generate memory under situations of hypoxia, in different brain region. Rats in the normal oxygen group that ate a diet low in fats but high in complex carbohydrates showed normal levels of CREB phosphorylation in the ...