Tag: "toxin" at medical news
Targeted Protein Toxin Effective Against Persistent Brain Tumors
...is drugis a compound created by linking diphtheria toxin
to a protein calledtransferrin that targets rapidly growing cells such as tumor cells. Nine ofthe 15 patients who were evaluated after this treatment had reductions in tumorsize, and the tumor disappeared completely in two patients. While these re...
Botox Treats Excessive Sweating, According To UCSF Study
...ctively with botulinum Aneurotoxin (Botox®), a toxin
derived from bacteria. "The finding offers patients with this condition a significant alternative tosurgery," said Richard Glogau, MD, UCSF clinical professor of dermatology. "This treatment can be completed in an office visit, requires no anesthesia...
UF Researcher Explores Complex Relationship Between Smoking And Fertility
...ng with fertility. Shiverick found that a toxin
in cigarette smoke, benzo(a)pyrene,actuallyinhibited the growth of cells that could migrate and develop intoendometriosis. "But if the chemical has the same inhibitory effect on the growth ofnormal uterine tissue, this would not be favorable ...
Emory University researchers say cholinergic agents may offer relief from tics in adults with Tourette syndrome
...re medications likeclonidine (Catapres), botulinum toxin
injections occasionally used to relievefacial tics and stimulants such as methylphenidate (Ritalin) used to relieveADHD symptoms. "Low doses of Tacrine seemed to address not only the tic symptoms butother symptoms like inattention, impulsivi...
Scientists use bacterial toxin to kill brain tumors
... and the Universityof Toronto (U of T) have used a toxin
produced by the same bacteria that causehamburger ...logyat the U of T. "Some E. coli strains produce a toxin
known as verotoxin. Ourearlier research has shown that, in the test tube, verotoxin kills certain br...
New medication effective against muscle disorder
...alled cervical dystonia.This new type of botulinum toxin
-- a medication frequently used to relievemuscle d...lityto lead a normal life. Injection of botulinum toxin
type A into affected muscles has been the primarytherapy for cervical dystonia. Botulinum toxin
Targeted toxins may revolutionize pain therapy
...idate for pain treatment is substance P-saporin, a toxin
thatselectively kills neurons that carry pain sign...proteinproduction and kills the cell. In rats, the toxin
blocks the development of extreme sensitivity topain--hyperalgesia. "We think that hyperalgesia is t...
Castagnolis discover compound in tobacco that may protect against Parkinson's disease
...at caused the brain to turn the contaminant into a toxin
that caused many of its users to develop the Parkinsonian symptoms. In the recent tobacco study, the Castagnolis discovered that TMN, found in tobacco smoke as well as leaves, did in fact interfere with MAO and protected the rodents against the toxi...
Landmark dialysis study findings could greatly simplify treatment of kidney disease with peritoneal dialysis
...the role healthy kidneys play in waste product and toxin
removal. Until now, many kidney specialists prescribing peritoneal dialysis have believed that increasing small solute clearances would result in better survival. Increasing small solute clearances can be achieved either by filling higher volumes ...
First European trial for new breast cancer vaccine
... two small inactive fragments derived from tetanus toxin
the bacterium that causes lockjaw. The researchers included DNA encoding the fragments, into DNA that they had made in the laboratory to code for a portion of the HER-2 molecule. The DNA vaccine is injected and taken up by the cells, which then man...
Jefferson researchers find protein signpost may indicate esophageal and stomach cancer
...lz says. She suggests a spray might be used with a toxin
attached to an antibody that binds to GCC. "You could deliver therapeutics and perhaps use it for diagnostics." Next, she says, she and her team would like to study GCC expression in a larger number of patients. They are also working to develop an a...
Other highlights in the April 17 issue of JNCI
... Center and his coworkers synthesized a diphtheria toxin
recombinant fusion protein (DTAT) and found that DTAT caused regression of glioblastoma tumors which had been injected into mice. DTAT had little or no toxic effect on the kidney, liver, heart, lung, and spleen. The authors conclude that DTAT may hav...
Newly published data show at-home dialysis therapy may benefit more patients
...ng PD small solute clearances a common measure of toxin
removal and kidney function on mortality outcomes in patients with ESRD. Until now, many kidney specialists prescribing PD have believed that increasing small solute clearances would result in better survival. However, ADEMEX researchers found th...
University of Pittsburgh researchers use botox to treat overactive bladder
ORLANDO, May 25 Botulinum toxin
A (BTX) injections, commonly known as botox, show promise as a treatment for a variety of lower urinary tract dysfunctions, according to a study presented by University of Pittsburgh researchers at the American Urological Association Centennial Celeb...
Botox proving successful at preventing headaches
...STON-SALEM, N.C. Small amounts of the most deadly toxin
known to man are proving effective at preventing d...s high as 92 percent using injections of botulinum toxin
to treat patients who didn't respond to headache medications. "Botox is becoming one of the main pre...
Toxin injections prove useful for spasticity after stroke
...l of Medicine. The report indicates that botulinum toxin
type A, also known as Botox, reduces disability ca...ss the benefit of one-time injections of botulinum toxin
type A. Allison Brashear, M.D., principal investigator and first author of the article, said the res...
Promising vaccine may provide long-lasting protection against malaria
... developed a unique vaccine that destroys a deadly toxin
produced by the parasite that causes malaria, whic...ew approach to controlling malaria by blocking the toxin
that is responsible for so many deaths," says Peter H. Seeberger, Ph.D., associate professor of chem...
Studies define biochemical structure that keeps blood pressure low, bypass grafts open
...ity to be attacked by other compounds and become a toxin
because it's very close to its receptor, to the sGC enzyme that it stimulates and then creates all the good things that it does," he said. They first confirmed the structure by using a process called immunoprecipitation, in which antibodies were used...
FINAL ALERT: RPB Science Writers Seminar in Eye Research to be held in Washington, DC Sept. 22-25
...e; and a novel vaccine to neutralize the bacterial toxin
responsible for much of the pain and corneal damage. GLAUCOMA: NEW DAY DAWNING. There's much new afoot in glaucoma research. What beckons: better diagnosis and novel treatments. Researchers report, for example, that with new, computer-based "mac...
Mayo Clinic discovers one more downside to alcoholism
... to two major causes: 1) high levels of ammonia, a toxin
that an unhealthy liver may no longer be able to convert to urea and excrete via the kidney and; 2) brain damage from alcohol. Mayo Clinic liver transplantation protocol requires that all patients receiving liver transplant for alcoholic-liver dise...
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