Tacrolimus Stops Rejection Of Kidney Transplants
...506) can halt or reverse unmanageable rejection of transplanted kidneys in three out of four cases says a report f...n-an unrelenting immune system assault against the transplanted organ-remains one of the principal problems of organ transplantation. This is the first multi-center...Study Shows Gum Disease Increases Risk Of Future Heart Disease
...ich represents a damaged area in the heart. The transplanted bacteria can cause the valve to become infected, and the accumulated clumps can block blood vessels. "Weve known for some time that oral bacteria can infect damaged hearts and that certain oral bacteria cause platelets to aggregate," Genco said....Researchers Begin Drug Trial In Hope Of Finding New Ways To Treat Acute Kidney Failure
... thedisease at a number of different steps even in transplanted kidneys," Star said. "This means that a less-than-perfect kidney could be transplanted. Itcould help increase the number of available kidneys, which would reduce thewaiting list for recipients considerably," Star said. Phase I of the...Cyclosporin Appears Effective In Treating Heart Disease
...orin, a drug commonly used to prevent rejection of transplanted organs,prevents HCM in rats and mice. The study was led by Jeffery D. Molkentin,Ph.D., a researcher in the division of molecular cardiovascular biology and aPew Scholar at Cincinnati Children's. HCM is an inherited form of heart disease that affects...UNC-CH Studies Show Medicine Can Reverse Osteoporosis From Transplants, Cystic Fibrosis
... immuno-suppressantssuch as cyclosporin to prevent transplanted tissue from being rejected. "Although these drugs prevent rejection, unfortunately they weakenbones," Aris said. "They impact bones in a half-dozen or more ways such as byblocking calcium absorption in the gut, by promoting bone resorption, ......patients, ranging frominfants to seniors, who were transplanted between 1989 and 1992, to determinetheir long-term survival using the anti-rejection drug developed at the UPMC. With 84 percent of the patients being hospital-bound at the time oftransplantation, the overall one-year and seven-year patient survival ...Encapsulating Insulin-Producing Cells For Possible Diabetes Therapy
... solidified by a quickflash of laser light to seal transplanted insulin-producing cells inside aselectively permeable capsule, thus preventing rejection by diabetics' immunesystems. An interdisciplinary collaboration, involving Duke's department ofchemistry as well as its medical center and School of Engi...New Drug Boosts The Power Of Traditional Cancer Therapies, UF Animal Studies Show
...ound that combretastatin was effective in battling transplanted and spontaneous tumors in animal models. Michael Horsman, a researcher on the second study who is affiliated with the Danish Cancer Society's department of experimental oncology, called the combretastatin results "very compelling, particularly in the......thy and cancerous cells. The stem cells canthen be transplanted back into the patients, providing a fresh supply of healthyblood cells and restoring bone marrow function. Traditionally, another growth factor, G-CSF, has been relied upon to stimulatestem cell migration into the bloodstream. However, the drug ofte...USC Researcher Lights Up The Immune System To Help Heart Transplant Recipients
...ecognize the very cells that are attacking the transplanted organ," Barr said. In the study, a total of 60 heart transplant patients were randomly assigned to receive either photopheresis (with standard therapy) or standard therapy alone. The patients treated with photopheresis were more than twice a...Best Use Of Angiostatin May Be To Enhance Radiation Therapy
...y used large (500mm3),rapidly growing human tumors transplanted into mice. As expected, the most effective therapy was the combination of simultaneousangiostatin and radiation therapy. What was not anticipated was how littleangiostatin was required to make a big difference, or how limited the benefitswould be fro...Lo-Cal Diet Slows Prostate Cancer In Animals, New Research Finds
... rat prostate cancer were transplanted into four groupsof cancer... The mouse experiment using transplanted human prostate-tumor cells also showed that a diet lower incalories ...Research Links Healthy Biological Clock To Longevity
...hen University of Toronto psychologist MartinRalph transplanted a new clock into hamsters whose own clocks had begun todeteriorate, they lived an average of four months longer than hamsters withoutthe transplant -- roughly a 20 per cent increase in their lifespan. A biological clock is a small piece of brain tiss......believes is necessary for long-termacceptance of a transplanted organ. Results of the study--the largest of its ki...cytes, or white blood cells, had migrated from the transplanted organs torecipient tissues, where they persisted years--in one case, for 29 years--aftertransplantat......cytes, or white blood cells, had migrated from the transplanted organs torecipient tissues, where they persisted y...cells continuing to coexistwith donor cells within transplanted organs. Such an observation providedconfirmation that in organ transplantation, surgeons are not on......ng transplants, 19 of which were male donor organs transplanted into femalerecipients. Graft outcome w...ound that the rate of graftsurvival (a functioning transplanted lung) with good function was 29% at 24months after transplantation for the male donor lung into fema......pears to significantly reduce the rejection riskof transplanted organs is currently being studied in multi-center ...ad" antibodies in theirsystems that would reject a transplanted kidney. IVIG contains "good" antibodiesthat block the ability of the bad ones to cause rejection. Us...New Strategy May Succeed At Extending The Life Of Transplanted Kidneys
...chance at a normal,active life. But, on average, a transplanted kidney continues to function foronly nine years. N...Center say anew strategy to extend the function of transplanted kidneys shows promise. In a study of 60 people who had received kidney transplants and were showing...Livers From Children Are Going To Adults, University Of Pittsburgh Review Of National Data Reveals
...s of all livers donated by children since1991 were transplanted into adults instead of their peers on the national...ceive the smaller segment while the largerpiece is transplanted into adults. Survival for patients who receive splitlivers is no different than for those who recei...Kidney Transplant Recipients Require Less Long-Term Care If They Receive Well-Matched Donor Organs
...A markers,had little effect on kidney rejection of transplanted kidneys. In the new study of 27,050 kidney...d surface markers increased. "Although the transplanted kidney remains functional in patients withmore mismatches, the patient doesn't do as well, and that ...