Transplant of pig tissue may reduce stroke size and damage
...protecting the brain and when additional tissue is transplanted into an animal model of stroke, it reduces stroke size by about 65 percent, Medical College of Georgia researchers report. "What we have seen is the reduction of the size of the stroke in the brain, and the animals that received the transplant showe...Biotech breakthrough in islet cell replacement for type 1 diabetes
...ultidisciplinary initiative to enhance survival of transplanted islet cells in patients with type 1 diabetes, linking Northwestern University researchers in transplant surgery, endocrinology, materials science and engineering, chemical and biological engineering and chemistry. The grant will complement other res...Pigment cell transplantation appears helpful for treating patients with stable vitiligo
... and colleagues investigated the efficacy of using transplanted pigment cells to treat 28 patients with vitiligo. Patients were divided into two groups: patients with stable vitiligo (no new depigmented patches in the past 12 months, n=19) and patients whose vitiligo was not stable (n=9). The researchers selec...Promise of stem cells amplified
...ls completed their maturation. When the OPCs were transplanted into rats just seven days after a spinal cord inju...umed GDNF production by withdrawing it. They then transplanted the genetically modified astrocytes into the brains of rats that served as animal models of either P...Olfactory bulb stem cells and Lou Gehrig's disease
...mal mice and froze them. Retrieved cells were then transplanted into the spinal cords of genetically engineered mi...evelop the equivalent of ALS. Animals that got the transplanted cells did develop disease symptoms, but did so about a month and a half later than non-transplanted ...Several new techniques show promise for spinal cord repair
...." New research shows that a special type of cell transplanted into injured rat spinal cord forms myelin-the insu...red--rats expressing green fluorescent protein and transplanted them into other rats' spinal cords that had been completely cut at the dorsal funicular location. Th...Blood transplants may be more harmful than bone marrow transplants in pediatric leukemia patients
...ients with acute leukemia aged 8-20 years who were transplanted between 1995 and 2000. This analysis was performe...e, a potentially serious complication in which the transplanted cells attack the tissues of the recipient. Chronic graft-versus-host disease was significantly high...Stem cells of limited use for cardiac muscle repair
...more-rigorous experiments, however, found that the transplanted cells are unable to take the crucial final steps. ... adult stem cells. "It's clear that the transplanted cells aren't growing, as we once hoped, into heart cells," McNally said, "but they may stimulate the...Stem cells to the rescue - or not?
...ally and colleagues from the University of Chicago transplanted BM-SP cells from normal male mice into female mice lacking delta-sarcoglycan an animal model of cardiomyopathy and muscular dystrophy to determine whether these stem cells would be recruited to skeletal and cardiac muscle to restore delta -sarcogly...Blacks and poor more likely to donate than receive many types of transplant organs
...ring a good tissue type match improves survival of transplanted organs but may make it harder for blacks to receive organs. Disparities that are both avoidable and undesirable are more concerning. For example, lack of health insurance may act as a barrier to transplantation among blacks and the poor....New marrow transplant method developed at Stanford may eliminate fatal side effects
...homas and leukemia, but in about half of the cases transplanted immune cells wind up attacking the patient's body,...raft-versus-host disease, without compromising the transplanted cells' effectiveness against cancer. The therapy entails adjusting the patient's level of a specific...Surgeons pinch more than an inch from the arm to rebuild a micropenis
...inal penis is incorporated into the surface of the transplanted skin. Patients receive a urethra to enable them to urinate, and an inflatable penile prosthesis to allow an erection to engage in sexual intercourse. UCL surgeons performed the operation on nine men aged 19 to 43 with a range of medical backgrounds,...Transplanted bone marrow cells reduce liver fibrosis in mice
...apan's Yamaguchi University, studied the effect of transplanted bone marrow cells on mice with liver fibrosis. Th... received carbon tetrachloride treatments. The transplanted blood marrow cells degraded collagen fibers and reduced liver fibrosis, exhibiting strong expression...U of MN researchers set new standard of care for adult cord blood transplant patients
...l the patient's bone marrow is destroyed, and then transplanted with two partially matched umbilical cords. The m...emotherapy and radiation. These patients were then transplanted with cord blood from either one or two donors. In this study, 89 percent of the patients engrafted ...Multi-center study finds therapy boosts kidney transplants in 'highly sensitized' patients
...patibility issues exist for all patients receiving transplanted organs, rejection risks are especially high for a ... years. For sensitized patients, the odds of being transplanted drop. According to the article, "the higher the PRA, the more difficult it becomes to find an immuno...Reducing anti-rejection meds after transplant shows less complications
...nt survival rate is 42 percent. An adult and child transplanted more than 14 years ago at the University of Pittsburgh are the world's longest surviving recipients of a liver-intestine transplant. In April 2001, the Centers for Medicare and Medicaid Services approved transplants of the small bowel, b...M. D. Anderson researchers discover key protein in psoriasis
...ng response. In another experiment, the scientists transplanted skin from their STAT3 mice to a mouse that produce... to be necessary for development of psoriasis. The transplanted skin did not initially develop psoriasis lesions. However, when the scientists injected activated T ...Kinder, gentler procedure gives superior results for stem cell transplants
...y knock out the patient's immune system to let the transplanted cells engraft, but then allow immune function to r...erity of graft vs. host disease, which occurs when transplanted immune cells attack various cells in the body. For the majority of patients who experienced graft vs...Animal studies show stem cells might make biological pacemaker
... surface. Sure enough, the signal started from the transplanted human cells, easy to locate because of their fluorescence. "We've answered three very important questions," says Xue. "We've shown that these human cells survived when we put them into the animals, they were able to combine functionally with th......te for Medicial Research in London, Raisman's team transplanted cells from this region into the injured spinal cord of laboratory rats, and found that the cells had a remarkable capacity to integrate into damaged pathways, laying a 'bridge' over the gap in the nerve fibres caused by injury. The team has now move...