Promise of stem cells amplified
...d the dopamine neurons to sprout new fibers and to transport the GDNF back to the neuron cell bodies, signs of improved neuronal health and function. "The study provides evidence that this delivery method might be used as a clinical tool for Parkinson's and Huntington's diseases," says Svendsen. Another group...Researchers monitor progression of Parkinson's disease by studying molecular changes in brain
...we are doing is developing the imaging of dopamine transport into a biomarker of disease progression," said Dr. Schwarz. "As a biomarker, that image provides us with much more than a picture. It gives us quantifiable data that can then be used to devise a general treatment methodology and to assess an individu...'Energy blocker' kills big tumors in rats
...be riddled with more of the "two-way streets" that transport lactate. And because 3-bromopyruvate looks very similar to lactate, it might travel those same roads, sneaking into cancer cells like a Trojan horse, suggests Ko. In her latest experiments, described in the Nov. 5 issue of Biochemical and Bioph...Lord Sainsbury praises the work of the UK's Innovative Manufacturing Research Centres
...or manufacturing to sports technology, healthcare, transport and e-manufacturing....Lab studies show two proteins prevented progressive nerve cell loss in Parkinson's disease
...o far." Genetically engineered viruses are used to transport genes and/or proteins into cells and have been used in gene therapy research for the last ten years. Just like a viral infection, they work by tricking cells into accepting them as part of their own genetic coding. The trick has been to alter the v...Envisat Symposium report day 2: GMES turns science to services
...cts will be used to monitor long-range atmospheric transport of air pollutants, while improved regional forecasts will be used by air-quality authorities in cities across Europe. Other speakers touched upon the research required to support GMES objectives, such as improved modeling tools and data fusion techn...Siberian forest fires partly to blame for Seattle area violating EPA ozone limit
...In the past, we haven't considered that long-range transport can bring in pollution levels that are significant," Jaffe said. "What we're finding is that these events can bring in significant levels of pollution, even to urban areas where the levels already are relatively high." In the spring and summer of 20...Children walk nearly as much as their grandparents did
... trips in each town. The researchers conclude that transport policy should pay far more attention to the needs ... form of travel that has been marginalized in much transport policy," says Professor Colin Pooley, the project leader. The research, which was based on detailed ...Novel 'delivery' method for nutrients wins Kaye Innovation Award for Hebrew university students
...evelopment of "nanovehicles" that can successfully transport the desired components through the digestive syste...ly formulated vehicles can successfully entrap and transport nutrients dissolved in nanodroplets or liquid-crystals that are 95 percent water. The current direct...Iron supplements help only certain non-anemic women
...in the blood and plays an important role in oxygen transport and utilization. When people consume iron-deficient diets, they first deplete stores of iron in the liver; at the final stage, they become anemic due to insufficient iron to produce new red blood cells. To prevent iron depletion, the researchers re...Three Harvard Medical School endowed chairs named simultaneously in sleep medicine
..., the tourism trade, emergency services personnel, transport industries, and the national security work-force. Addressing sleep disorders has serious implications for public safety, the treatment of disease, and quality of life. These three new chairs will aid the Division of Sleep Medicine as it provides grea...Researchers define mechanism that enables stem cells to track migrating brain tumor cells
...cells appear to be effective "delivery systems" to transport cancer-killing gene and immune products. But not all neural stem cells take on this tracking role. Now researchers at Cedars-Sinai's Maxine Dunitz Neurosurgical Institute, using mouse and human cells, have defined a subset of neural stem cells that ...Special incubators allow high-quality imaging of critically ill newborns
...cated, because of concerns for their safety during transport and during the procedure." Logistical challenges in providing good diagnostic imaging of newborns are considerable and include monitoring circulation and maintaining constant control of temperature, airflow and humidity. Consequently, few newborns ...Genetic mutation linked to infant lung disease
...here surfactant is stored. "This kind of defective transport could lead to the production of abnormal surfactan... alternatively, a mutated ABCA3 gene could fail to transport out lipids toxic to surfactant function," he says. Researchers zeroed in on ABCA3 as a cand...Inhibitors prevent aggresome formation associated with some forms of ALS
... protein and specialized proteins in the cell that transport cargo, the dynein/dynactin transport machinery. The authors note that a recent study by Kawaguchi et al. showing that HDAC6 is directly i...American Thoracic Society Journal news tips for March 2004
... A missing gene that regulates chloride and sodium transport across cell membranes causes problems, leading to dehydration and the production of very sticky secretions. In CF, the mucus-producing glands of the lung produce thick, abnormal secretions that clog the airways, damage the lungs, and form an environ...Student builds micro biosensor chip to move DNA molecules
...t allows us to generate an electric field that can transport molecules to a designated area for study." The chips made by Wang and Simone take advantage of the natural negative charge possessed by DNA or a surface charge imposed on the molecules. A tiny drop of liquid containing the DNA is placed atop the chip...2004 Award for Basic Research in Biological Mineralization goes to Dr. Yoshiro Takano
...wden. He has been credited for his work on calcium transport in the enamel organ as well as for other studies related to biological mineralization. The IADR Basic Research in Biological Mineralization Award, supported by Unilever Oral Care and consisting of a cash award and a plaque, is designed to stimulate, ...New policy stops transplant heart gaming put potential still exists
...ithin a specific geographical region. Since long transport could damage cadaver hearts, organs obtained in an OPO are used primarily within the geographical boundaries of that same OPO. Some OPOs have only one heart transplantation center within its boundaries while others have up to nine centers that must c...Jefferson scientists unlocking secrets of cholesterol transport in body
... are integral parts of an unidentified cholesterol transport system in the intestine. A better understanding of the mechanisms behind cholesterol transport and absorption in the intestine could lead to improved therapies for obesity, diabetes and cardiovas...