Alcohol researchers identify new medication that lessens relapse risk
...a 12-weekdouble-blind, placebo-controlled clinical trial that patients who receivednalmefene were 2.4 times less likely to relapse to heavy drinking than those whoreceived a placebo. "This study again demonstrates the promise of pharmacologic agents to work withstandard behavioral treatments in the treatm...... in the United States and Canada during a clinical trial called PURSUIT("Platelet glycoprotein Iib/IIIa in ...ugh the Latin American patients whoenrolled in the trial tended to be younger, shorter, weighed less and had fewerpast heart procedures. "The presence and ex...Statement from Dr. Claude Lenfant, director, NHLBI and Dr. Phillip Gorden, director, NIDDK
...ntion of Cardiovascular Disease in Diabetes (PCDD) trial will study thebenefits of intensified control of h...The Study of Health Outcomes of Weight Loss (SHOW) trial willfocus on the benefits of weight loss in obese individuals with diabetes.Together, they will prov...Heart failure deaths reduced by 30 percent with new drug regimen
...Randomized Aldactone Evaluation Study (RALES), the trial defiescurrent thinking that spironolactone and oth...ses at Searle,which sponsored the study. The RALES trial helps to define the important role ofaldosterone in heart failure and opens the door to the research...New HIV drug intervention cheap and effective
...irapine and has recently been tested in a clinical trial called HIVNET 012. The nevirapine regimen resulte...d to a short-course AZT treatment. Results of the trial are also published in the current issue of The Lancet. "The results were pretty stunning," said El...Study suggests why estrogen not helpful against heart disease
... American Medical Association. The first clinical trial testing the effect of hormone replacement therapy on post-menopausal women with known coronary artery disease showed little or no beneficial effect fromestrogen. ...Drug offers new hope for victims of cardiac arrest
...e heart back to normal beating. A clinical trial performed by University of Washington researchers,... to men. Kudenchuk noted that the clinical trial is the first of its kind tocompare the effectiveness of an anti-arrhythmia medication with all stand...OHSU researchers test medication that targets fever without side effects
...ne of the sites involved in a multi-state clinical trial of the drugrofecoxib. The testing showed that the drug reduced fever without appearing toaffect other important body functions. To come to this conclusion, patients with fever were solicited throughadvertisements. Some subjects were given the drug r...Antibody solution may prevent adhesions after surgery
...tion with Dr.Cheresh, in a randomized, prospective trial of adhesion prevention in womenundergoing laparoscopy for endometriosis and/or pelvic adhesive disease, Lesseysays. "If this antibody can be shown to be efficacious in preventing adhesionsin women, a larger multi-center approach will be organized." T...Yale Medical School to begin clinical trial for glaucoma medication
... The patients who will be enrolled in the clinical trial will be those alreadyafflicted with glaucoma. One third will be given 10 milligrams of memantine, onethird will be administered 20 milligrams, and one third will be given a placebo,Dr. Shields said. "The study will go on for four years and during tha...First brain cancer surgeries using new space-age probe are successful
...g Administration approval to use the LED probe ona trial basis in the removal of children's brain tumors. To remove these tumors,Whelan's technique involves injecting the patient's bloodstream with a drugcalled PHOTOFRIN, a light-activated drug, currently approved in the UnitedStates for the treatment of c...UNC studying new drug against ovarian and endometrial cancers
CHAPEL HILL, N.C. - A clinical trial at the University of North Carolina atChapel Hill ...,400 deaths. The ongoing LY353381 clinical trial at UNC continues to enroll newpatients. Women interested in entering the study should contact Dr. Va...New biomarker for cervical cancer
...ng cervical cancerscreening. The clinical trial will examine cervical smears for telomerase, aprotein released into cells when chromosomes shorten, stick together and becomegenetically unstable. The protein helps rebuild eroded telomeres, the caps atthe ends of chromosomes. Its presence in cervica...Treatments reduce strep-triggered symptoms of OCD and tics in some children
...mal behavior. Of the 29 children who completed the trial (19 boys, 10 girls), 10 received PEX,9 IVIG, and 10 placebo. Both PEX and IVIG produced substantial improvement inobsessive-compulsive symptoms, anxiety, and overall functioning; PEX alsoimproved tic symptoms. Ratings done one month after treatment......h Outcomes of Weight loss (SHOW). The SHOW trial will involve 6,000 obese people who have adult-onset(type 2) diabetes, and test whether weight loss will reduce the adverse healthproblems commonly encountered by diabetics, especially cardiovascular disease. "Weight loss is associated with i....... Patients who are eligible to participate in the trial must have a confirmeddiagnosis of stage IV advanced breast cancer; have minimal tissue and organdamage; be relatively healthy with no major symptoms; and have not used anyexperimental agents, herbal medication or anti-tumor therapies for at leastthre...Researchers discover potential new approach to treating cystic fibrosis
...established a specialized networkof seven clinical trial centers to expedite the early phases of clinical trials. "Although a number of steps remain before the benefit of DHA to patientsis known, this exciting research represents an entirely new strategy to correctand possibly even prevent some of ...Results of NUVANCE phase I/II asthma trial presented
...olerated MADRID, SPAIN - Results of a Phase I/II trial of NUVANCE (soluble IL-4 receptor), an investigati...o-controlled, randomized, double-blind, Phase I/II trial was conducted in 62 adults with moderate persistent asthma, in which symptoms such as wheezing, shor......e three-year, randomized, double-blind,multicenter trial (110 study centers in North America) participants wererandomized to receive either a daily oral treatment of risedronate (2.5 mg or 5mg) or placebo. Each woman also took 1,000 mg of calcium each day, and those whohad vitamin D deficiency took up to 5...Wake Forest to coordinate huge national study to prevent cardiovascular disease in diabetes
...nics. "This is the most important clinical trial ever done addressing theprevention of heart diseas...ple with diabetes," Goff said. "The results ofthis trial will affect the treatment of millions of patients with diabetes fordecades to come." In addi...