Heart Experts Call For Action Against Missed Opportunities To Prevent Heart Disease In Women
... healthy lifestyle, which may confound theclinical trial results and make them uncertain." The panel also noted that current national recommendations might not beaggressive enough in treating elevated blood cholesterol in women. It suggeststhat clinicians consider a lower target level of blood tri...... weremonitored in this study. All patients in the trial were diagnosed withlate-stage AIDS (patients enter... be reviewing the results of the LEUKINE Phase III trial withthe FDA this spring," said Peggy Phillips, Immunex senior vice president ofpharmaceutical develo...Combination Therapy Improves Chances Of Surviving Esophageal Cancer
...combination treatmentin the randomized part of the trial and 14% of those in the "nonrandomized" partwere alive, compared to none of the patients who received radiation alone.......a. Detailed data regarding this clinical trial with a more completeanalysis will be presented at ... The most common events reported in this trial in patients receivingENBREL were mild to moderate injection site reactions that did not complicatetr...Wistar scientist awarded American Cancer Society grant for research on tumor killing cells
...t from theAmerican Cancer Society for a Phase I/II trial of TALL-104 cells in patientswith metastatic melanoma. TALL-104 is a "killer" cell line derived from the cells of a child with a rareform of T-cell leukemia. Dr. Santoli has found that TALL-104 cells canrecognize and selectively kill malignant cells...Second Annual AIDS Vaccine Day Honors Volunteers Nationwide
...understand the concerns of prospective HIV vaccine trial volunteers. One Phase III study that is testing AIDSVAX, a bivalent gp120 vaccine developedby VAXGEN, opened in the summer of 1998 and is expected to be completed in 2001. For information about events in specific areas, contact: Abt Associates, In...Margin Width The Key To Control Of Ductal Carcinoma In Situ Of The Breast
..." says Silverstein. "In defense of the NSABP, its trial was designed more than 14 years ago," saysSilverstein. "At that time researchers were asking a single broad question: Doesradiation therapy benefit patients with ductal carcinoma in situ treated withbreast preservation? The answer to that question is......FamilyMedicine, is the first randomized controlled trial of the effectiveness ofenvironmental interventions and assistive devices in maintaining independenceand reducing home-health-care costs among home-based frail elderly "The study demonstrates that a relatively inexpensive intervention canresul...Immunex Advances CD40 Ligand To Phase II Clinical Trial In People With Metastatic Kidney Cancer
...NX) announced today that it haslaunched a Phase II trial of the investigational agent CD40 Ligand (CD40L) i...y trials, Immunex is moving forwardwith a Phase II trial of CD40L in metastatic renal cell carcinoma," said AnnHayes, M.D., senior vice president, medical de...Biological Markers Found That Correlate To Esophageal Cancer Treatment Success
...correspond with reality. This national esophageal trial is a multi-centerrandomized study in which 250 patients will receive the tri-modality therapy and250 will receive surgery alone, which is the standard treatment. The markerswill be linked again to response to treatment and survival in both groups.......n a National Cancer Institute-sponsoredmulticenter trial that will study the role of SLNs in breast cancer....Retrospective Statistical Analysis Corroborates Early Results Of Randomized Breast Cancer Trials
...patients with metastaticbreast cancer, within each trial or across the trials. Berry looked fortreatment-related differences within ABMTR, but found none. Thus the twoseparate patient groups were compared to see if the high dose chemotherapy usedin ABMTR provided any survival benefit for metastatic breas...Breakthrough New Therapy Uses Antibody-Targeted Chemotherapy To Fight Leukemia
...results continue to emerge from a pivotal Phase II trial in the U.S.,which involves patients who experienced a relapse following initial AMLchemotherapy. CMA-676 given alone appears to produce remission among 36 percentof patients- a rate comparable to that of standard combination chemotherapyregimens. T...Treatment-Resistant Depression: Results of Latest Electromagnetic Stimulation Study Show Promise
...chool of Medicine andhas collaborated on the open trial with William McDonald, M.D., associateprofessor of psychiatry and behavioral sciences at the Emory University Schoolof Medicine, and others. "Sixty-four percent of patients were rated 'very much improved' or 'muchimproved' on the (CGIC) Clinical Gl...Progress In Cancer-Vaccine Studies: Simpler, Safer Approach Producing Encouraging Results
... the maximum tolerateddose of a new drug, but this trial indicated that the best dose was about onetenth of the maximum dose -- suggesting that dosing trials of biologic therapiesrequire a radically different design. At moderate doses, IL-12's most seriousside effects were tenderness at the injection site,...Sniffing Out The Promise Of Anti-Angiogenesis Therapy
... Parkash Gill, M.D., haveshown in a human clinical trial that a small peptide, in the form of a nosedrop, m...day, May 16, at11 a.m. In Phase II of the clinical trial of IM862-from which the data presented weretaken-Gill, a professor of medicine and pathology at the ......dition,preliminary results of the first-ever human trial involving children whoreceived bone marrow injecti...nd non-self. Thisstudy represents the first human trial of its kind. Following are summaries of the results of these clinical studies with contactinformatio...Mayo Clinic Study Finds Costs For Cancer Clinical Trials Comparable To Costs For Standard Treatment
...anges withrespect to Medicare coverage of clinical trial costs. As a matter of federalpolicy, Medicare doe...pation in cancer treatment trials from the date of trial entryuntil either death or 60 months following entry into the trial. Case subjectswere residents of...Evidence Shows Drug-Psychotherapy Combo Effective For Chronic Depression
...The research includes a 16-week continuation trial for patients who respondpositively to nefazodone or to the combination treatment in the acute phase followed by a 52-weekmaintenance treatment to evaluate the drug versus a placebo. "The evidence now exists that the combination of ......ty of these men are still enrolled in the clinical trial andcontinuing treatment at this time. "Our findings suggest that PC-SPES may have efficacy as a treatment for somemen with prostate cancer," said Eric Small, MD, UCSF assistant clinicalprofessor of medicine, co-author of the study. "However, as of ...