Not enough evidence that multivitamins prevent infections in the elderly
...p prevent infections. Researchers identified eight trials evaluating the effect of multivitamin and mineral supplements on infections in elderly people. Although three studies reported fewer days spent with infection, overall the evidence was weak and conflicting. The evidence does not support a policy rec...International breast cancer prevention study launches in the United States and Canada
..., conducts and analyzes national and international trials of cancer therapy, including trials for new cancer drugs, cancer prevention and supportive care to improve quality of life for people wi...Pitt marks 50th anniversary of its Salk polio vaccine with reunion, scientific symposium
...rabilia are children who participated in the pilot trials at local schools, who recall their fear of the long needles but their greater fear of the disease the vaccine was designed to prevent. Children not as lucky, who got polio and had been confined to hospital wards, some in total isolation from their pa...Unexpected benefit seen in treating HER-2 breast cancer with new preoperative drug combo
... to Buzdar, and several large and lengthy clinical trials are now under way to test for cancer recurrence and survival after use of Herceptin with chemotherapy. But researchers at M. D. Anderson wanted to test use of the drug combination in patients with earlier stage breast cancer, defined as stage II to I...OHSU scientists test medication to treat involuntary weight loss
...cle mass. Researchers now hope to conduct clinical trials where both healthy human patients and those suffering from cachexia receive related oral medications to determine the drug's safety and effectiveness. "We believe the results obtained in this collaborative study with OHSU will provide an importa...Lack of clinical trial participation may contribute to lower survival rates
... clinical trials. Participation in cancer clinical trials has been shown to improve survival. Young adults with Kaposi Sarcoma have shown significant survival and mortality benefits after improvements in clinical trial participation. Archie Bleyer, M.D. of the M. D. Anderson Cancer Center in Houston and col...Hopkins begins human trials with donor adult stem cells to repair muscle damaged from heart attack
...ilable when and if Phase II and Phase III clinical trials proceed. The Hopkins team expects that after injection, the adult stem cells will migrate to the damaged areas of the heart muscle, responding to chemical signals released by the heart after an infarct that triggers a repair response from the bone ...US attempting to flout ethical practice for patient trials abroad
...cal ethics that protects patients who take part in trials is not necessary for studies conducted abroad, states a comment in this week's issue of THE LANCET. The 2000 Declaration of Helsinki, produced by 82 national medical associations, states that: "At the conclusion of the study, every patient entered in...Stanford patient is first to test new treatment for peripheral arterial disease
... 650-725-9810. This is the first phase of clinical trials for the drug-eluting stent. If proven safe and effective in this phase - expected to be completed in a little more than a year after the 60 patients have been treated - a second, larger trial will look more closely at the long-term success of the ste...ESC releases the first European Guidelines on Percutaneous Coronary Interventions (PCI)
...d be considered at an early stage. 9. Randomised trials that transfer the patients for primary PCI to a 'heart attack centre' have observed a better clinical outcome than thrombolysis. This has been observed despite the delay, due to transportation, between randomisation and the start of the treatment. 1...African-American women with endometrial cancer have more aggressive cancer than Caucasian women
... a retrospective study of data from four treatment trials carried out by the Gynecologic Oncology Group (GOG) in a clinical trial setting where patients receive similar care, to determine if outcomes remain poor for African-American women with endometrial cancer. The GOG is an NCI-funded national cooperati...New self-help technology set to combat eating disorders
...ed 13 to 20) affected by bulimia nervosa. Initial trials of the first stand-alone computerised treatment for eating disorder patients have been very successful and all patients involved in the pilot made significant improvements. The CD-ROM proved to be particularly effective in reducing vomiting and laxat...Diagnostic test for range of blood disorders on the horizon
...ostic test and the scarcity of randomised clinical trials make management of these diseases especially challenging. Tony Green (Cambridge Institute for Medical Research, UK) and colleagues analysed a candidate gene called JAK2 in 140 patients with myeloproliferative disorders from haematological clinics in...The European Society of Cardiology launches Women at Heart
... profiles. Women are under-represented in clinical trials and their CVD clinical manifestations are less wel...sion Increased representation of women in clinical trials Analysis of the ESC Euro Heart Survey databases to yield specific data on women and CVD, such as com...PillCam enables study of esophagus by swallowing a pill
...ads UT Southwestern's endoscopy services. Clinical trials already have shown that its accuracy is comparable to a traditional endoscopy. PillCam ESO is not recommended for people with swallowing disorders, pacemakers, or known or suspected gastrointestinal obstruction, said Dr. Ulrich. An endoscopy is still...Protecting human subjects focus of national FDA conference at UH
...lving the protection of human subjects in clinical trials and the organization's oversight role. Offering a number of panel discussions that provide a wide range of perspectives from the federal government, private industry and academia, many notable figures will be in attendance, as well as giving presen...Vitamin E may not prevent cancer or cardiovascular events, but may increase risk for heart failure
...to background information in the article. Clinical trials have generally failed to confirm benefits, possibl...ure events including all completed large vitamin E trials is strongly recommended." "In conjunction with its lack of efficacy, the potential for harm suggeste...Earlier use of prostate cancer vaccines urged by Hopkins scientists
...relapse and helps stall cancer growth. No clinical trials are yet available for the earlier vaccine regimen. Prostate cancer is the leading cause of cancer deaths in American men. The average time to relapse after beginning hormone therapy is approximately two years. The research was conducted with collabo...GlaxoSmithKline receives unanimous favorable recommendation by FDA Advisory Committee for Boostrix
...e FDA Advisory Committee reviewed several clinical trials which included safety and immunogenicity data from one pivotal trial, which studied Boostrix in more than 3,000 adolescents in the United States, aged 10 to 18. The Phase III clinical trial showed Boostrix to be comparable to a U.S.- licensed Td vac...Treating depression helps slow physical decline in older adults, study shows
...k of medications or managing money. Prior clinical trials of successful treatment of depression in this age group reported improvement in emotional functioning, but had not demonstrated that improved emotional health also translated into improved physical health. Older adults with depression report persiste...