Columbia study finds hemophilia therapy dramatically improves outcomes for bleeding stroke
...upportive. RFVIIa is currently entering phase III trials as an investigational treatment for ICH. If appro...e new research projects: one of the first clinical trials of statin medications as a potential stroke treatment; an imaging study of brain reorganization caus...Hormone therapy increases risk of urinary incontinence
...ble-blind, placebo-controlled, randomized clinical trials of menopausal hormone therapy in 27,347 postmenopa...xyprogesterone acetate [MPA]), or placebo. The WHI trials were designed to evaluate the effects of MHT using estrogen and progestin or estrogen alone in preve...Investigational transplant drug effectively preserves kidneys while avoiding toxic side effects
...s an important step in establishing human clinical trials to develop an effective alternative to current anti-rejection therapies. Findings from one of the nonhuman primate studies appear in the March issue of the American Journal of Transplantation, which currently is online and appeared in print on Februa...Insurance incentives might help smokers quit, study says
...g both the content and quality of existing medical trials on a topic. Previous research shows that smoking-cessation treatment, including counseling, nicotine replacement products and the antidepressant drug bupropion can increase the chances that a smoker will give up the habit. But "costs are a significan...Exercise therapy builds strength, mobility in MS patients
...g both the content and quality of existing medical trials on a topic. Multiple sclerosis is a degenerative nerve disease that damages the protective fatty sheath around nerves in the brain and spinal cord. Some patients experience a pattern of disease flare-up followed by disease free periods, while others...Diabetes a bigger heart disease risk for women than for men
...to use the insulin produced. Data from randomized trials of individuals with diabetes would clarify these issues. Besides continuing to seek data on the sex-specific relative risk for CHD related to diabetes, researchers at the George Institute are leading a large scale randomized trial Action in Diabetes ...How often should women get mammograms?
... which made use of data from several past clinical trials of mammography screening and from cancer databases...e real world, say the scientists, because clinical trials would require hundreds of thousands of volunteers following a variety of schedules over many years t...Suicidal behaviour caused by antidepressants 'cannot be ruled out'
...rugs. In the first study, researchers analysed 702 trials involving over 87,000 patients with depression and... also warn that major limitations in the published trials may have led to underestimates of the risk of suicide attempts. The second study reviewed 477 trials...Medication helps alcoholics control drinking
...g both the content and quality of existing medical trials on a topic. Dr. Joseph Volpicelli, of the University of Pennsylvania School of Medicine, has been conducting research on naltrexone use for alcohol dependence since the early 1980s. Naltrexone blocks the brain's receptors for natural painkillers, kno...Drugs aid weight loss among type 2 diabetes patients
...g both the content and quality of existing medical trials on a topic. Although a variety of other weight los...h various lifestyle interventions, but most [drug] trials include relatively weak lifestyle programs, perhaps in part to better reveal the medication effects,...Hormone therapy controversy raises drug safety issues
...ding the reporting of negative as well as positive trials of new or approved drugs," she said....Researchers confirm Vioxx nearly doubled cardiovascular risks in cancer prevention study
...k we can tell this from this one trial or from the trials that are out there at the moment. That's going to be the real question." The investigators examined the use of cardio-protective aspirin among patients and found that it did not skew findings on the overall risk of Vioxx treatment....No increase in sexual risk taking among gay men in HIV-study
...that gay men can participate safely in HIV vaccine trials without a false sense of security that could lead to greater sexual risk-taking and new infections," said lead author, Dr. Tom Lampinen. The findings emerged during the world's first clinical test of a preventative vaccine, AIDSVAX. The study data a...COX-2 inhibitors associated with blood pressure elevation
CHICAGO An analysis of 19 randomized controlled trials involving COX-2 inhibitors (selective cyclooxygena...s, analyzed data from all 19 randomized controlled trials of COX-2 inhibitors published before May 2004, with a total of 45,451 participants for whom blood pr...Study finds new designer drug is potent treatment for chronic myelogenous leukemia
..." AMN107 has been started in early phase clinical trials at M.D. Anderson Cancer Center, and if it proves safe to administer, will be tested for effectiveness in CML patients at Dana-Farber and other sites. If the drug is effective, the next task will be to determine the optimal way of using it whether al...14-year study finds that quitting smoking adds years to life
...sed on data from the Lung Health Study. Randomized trials like the Lung Health Study are widely regarded as the gold standard for proof among clinical studies. "We know that people who smoke should quit smoking," said one of the study authors, John E. Connett, PhD, professor of biostatistics of the Universi...New highly active agents against sandfly fever
...s, others have antiretroviral activity. Biological trials in the mouse have already confirmed their properties and therapeutic efficacy. Parasitic diseases, especially leishmaniases and trypanosomiases, kill hundreds of thousands of people every year in the world, mainly in the countries of the South. The ...Northwestern Memorial Hospital receives $10 million commitment to support preeminent heart program
...e, is currently participating in about 50 clinical trials and is greatly expanding its clinical research inf...ar Institute. "In the near future, the clinical trials unit will investigate new ways to treat heart failure and to refine the use of implanted devices to ...Stem cell therapy for spinal injury
...ts are important for planning of stem cell therapy trials on patients with spinal injury. Spinal injury confines some 150 Swedes a year to wheelchairs. The damage cause the loss of movement and sensation below the level of injury. A research team at Karolinska Institutet has now shown using rat models that ...Leukemia drug breakthrough study in New England Journal of Medicine
...ata from two recent confirmatory phase II clinical trials performed nationwide involving more than 350 patients with red blood cell transfusion-dependent MDS - to the U.S. Food and Drug Administration in a new drug application (NDA) for Revlimid as an innovative approach to treat the anemia of MDS patients ...