Mount Sinai stroke prevention trial published in JAMA
...pies." SPORTIF V was one of two Phase III clinical trials involving 7,329 patients. SPORTIF III, an open-label trial previously conducted outside North America, found that patients taking ximelagatran experienced no more strokes or bleeding than those on well-controlled warfarin. In SPORTIF V, 63 patients ...UCI study uncovers how plaque in neck artery leads to stroke-inducing blood clots
... specimens from two of the most important clinical trials in the history of stroke research: the North American Symptomatic Carotid Endarterectomy Trial and the Asymptomatic Carotid Atherosclerosis Study. Fisher's study constitutes the only formal interaction between these two historically important studies...Early supported discharge services can reduce long term dependency for stroke patients
...l services. The greatest benefits were seen in the trials evaluating a coordinated multidisciplinary team an...s with mild to moderate disability. Five of the 11 trials reported an economic analysis. All concluded that savings from fewer hospital-bed days were greater ...Canadian neurologist wins highest award as American Stroke Association honors five
...elheim. Marler is associate director of clinical trials for the National Institute of Neurological Disease...INDS) and is recognized for leading major clinical trials resulting in more effective drug treatment of stroke. Marler was project leader for the NINDS tPA ...Suffering from fatigue, abdominal discomfort or bloody diarrhea?
...uated accurately in clinical practice and research trials without frequent lower endoscopies. The results fr...nts may be more willing to participate in clinical trials of new treatments if there are not so many colonoscopies involved."...New bedside tool gauges mortality risk in heart failure patients
...ay provide a more effective way to design clinical trials for evaluating heart failure therapies since researchers now have the ability to easily categorize patients by high and low mortality risk. The study was funded by Scios, Inc., a biopharmaceutical company and member of the Johnson and Johnson Family...AHA urges earlier diagnoses, referrals for PCI in women
...s of gender-specific evidence compiled in clinical trials over the last two decades, Lansky said more such trials are needed. "Our statement is based on the gender-specific evidence we have available to us as heal...Treatment for brain tumor does not always follow recommendations
...ffective in many others. At the same time, phase 1 trials in oncology that have traditionally excluded patients with brain tumors should be made more widely available to those with malignant glioma ," the editorialists write. "There are few proven risk factors for the development of brain tumors. It is diff...Neoadjuvant and adjuvant systemic therapy for breast cancer give equivalent survival, study finds
...agues performed a meta-analysis of nine randomized trials that had included nearly 4,000 breast cancer patients. The patients had been treated with systemic therapy either before or after surgery and/or radiation therapy. There was no difference between neoadjuvant and adjuvant systemic therapy in terms of ...Other highlights in the February 2 JNCI
...ng Angiogenesis Drugs Reviewed Designing clinical trials of angiogenesis drugs--drugs intended to cut off the growth of tumors' blood vessels--is difficult because it can take a long time for a drug's effect to be observed. Because antiangiogenic and antineovascular therapies are designed to affect the abn...No magic pill for treating dementia symptoms
...ay be effective. "Larger, well-designed controlled trials of non-drug interventions are needed," said Sink, an assistant professor of internal medicine geriatrics. The authors said that additional studies of drug therapy are also needed and that a large multi-center center study now under way to compare ...Brain tumor treatment can vary greatly, according to new JAMA study
...cipation in well-designed, well-conducted clinical trials enables us to answer questions about the value of new therapies with the hope of improving survival rates. The systematic evaluation of new treatments also prevents the widespread use of unproven, potentially toxic therapies. We need patients to part...Calcium and vitamin D most effective for treatment of Crohn's-related bone loss
...nd smoking cessation. Further randomized clinical trials are underway to determine if newer bone-building drugs will have additional beneficial effects on building bone mass in Crohn's patients. The results of those studies will not be available until next year. Until then, researchers suggest vitamin D ...Testosterone supplements for elderly men
The University of Manchester has just launched trials to investigate whether increasing the testosterone levels of frail elderly men could improve their strength, energy and mobility. The study is the first in the world to examine the impact of testosterone treatment on this age-group, and is being led ...Need better social research but it doesn't come cheap
...gthy sessions more like those used now for medical trials - with costs to match. Professor Loomes points out that many decisions about public policy are subject to political processes which for countries with elections every three to five years may be heavily influenced by shorter-term factors. In such a ...First US kidney cancer vaccine trial underway at Columbia
...normal cells. Trovax has shown promise in similar trials conducted in Europe in colon cancer. About Trovax Trovax belongs to a class of medicines called a vaccine. Trovax consists of a virus that has been changed so that it is no longer infectious and carries a gene for a protein called 5T4. This protein...Biochip for detection of inflammatory bowel disease
...xample. This biochip has recently started clinical trials in Spain, Germany, the UK, Holland and the Czech Republic using more than 4,000 donors....Reviparin effective in reducing risk of death after heart attack
...r spent on evaluating other approaches in clinical trials and using other therapies in practice." "What does...house of cards on a series of neutral 'equivalence trials or small outcome trials. Given the modest advantage of low-molecular-weight heparin in general in th...A global treatment for iron deficiency
...hese side effects. When it was tested in clinical trials in Bangladesh and Ghana, all of the mothers survey...ues summarize the results of seven community-based trials of using Sprinkles in four different countries. They found that Sprinkles were just as good as ferr......e of the project. The product is currently in the trials stage with patients, after which it will be launched on to the market by EuroOrtodoncia, possibly in the second half of 2005....