NIAID begins enrolling volunteers for novel HIV vaccine study
...frican Americans and other ethnic minorities. The trials will take place in the following locations: North America: Atlanta, Boston, Chicago, Denver, Houston, Los Angeles, Miami, New York, Philadelphia, St. Louis, San Francisco, Seattle, Toronto South America: Iquitos and Lima, Peru Caribbean: Sant...Study estimates number of excess cases of coronary heart disease caused by Vioxx
...to rofecoxib use were fatal. "In the future, when trials show that a new treatment confers a greater risk of a serious adverse effect than a standard treatment, we must be much more careful about allowing its unrestrained use." In an accompanying commentary Simon RJ Maxwell and David J Webb (University of ...Vaginal hysterectomy leads to better outcomes than abdominal surgery
...g both the content and quality of existing medical trials on a topic. In a vaginal hysterectomy, surgeons remove the uterus through the vaginal opening. Vaginal hysterectomies are usually performed when the uterus is a normal size. Abdominal hysterectomies, where the uterus is removed through an abdominal o...Steroids increase death risk from traumatic head injury
...g both the content and quality of existing medical trials on a topic. Corticosteroids are anti-inflammatory hormones used to treat all kinds of inflammation, from joint injury to asthma. They differ from anabolic steroids, the sex hormones like androgen, which are typically used to increase muscle mass and ...Routine use of nose-to-stomach tube slows recovery from abdominal surgery
...nded rational." A 1995 review of abdominal surgery trials showed that except for vomiting and bloating, pati...his co-authors identified 28 randomized controlled trials of emergency or elective abdominal surgeries. They did not include studies of laparoscopic surgeries...Clinical trial participants fare no better, no worse than other patients
... published against a backdrop of debate about drug trials for popular pain-relievers and about whether trial...wever, say the rigorous standards for inclusion in trials and the nature of those who conduct and participate in them mean that when a new drug or treatment i...Annual mammogram, doctor visits are enough for breast cancer follow-up
...g both the content and quality of existing medical trials on a topic. The new analysis is an update of a 20-year-old Cochrane report on the topic. The current review includes four randomized controlled trial studies of 3,055 patients that compare different types of breast cancer follow-up care. After analyz...Antioxidants have no effect on Lou Gehrig's disease
...g both the content and quality of existing medical trials on a topic. ALS is a fatal disease that causes deterioration of motor nerve cells in the brain and spinal cord. Although researchers are still unsure about the exact causes of the disease, some have suggested that nerve cells in ALS patients are dama...Counseling encourages exercise; environment changes may help
...g both the content and quality of existing medical trials on a topic. Hillsdon and colleagues reviewed 17 st...der. All of the studies were randomized controlled trials that compared different ways to encourage sedentary adults to become more physically active. The stu...Vioxx went mostly to patients who didn't need it, Stanford researcher says
...en Vioxx was pulled from the market after clinical trials showed that it posed significant risks of heart attacks. Similar findings were also recently reported for Celebrex, although it is still available. What makes the widespread use of COX-2s so troubling is that they aren't any more effective at control...Brenner Children's Hospital named to NIH Pediatric Heart Network
...dren's hospitals in the nation conducting clinical trials on patients with heart defects. "This is a real ho... of the network. Researchers will conduct clinical trials to find the best treatment methods for children suffering from heart conditions that may result in h...Cord blood transplantation now a viable option for adult leukemia patients
... investigation of this approach in larger clinical trials is needed to determine the full impact of this transplant procedure for adults and larger adolescents," said George Q. Daley, M.D., Ph.D., Associate Director of the Stem Cell/Developmental Biology research program at Children's Hospital Boston....Spinal repair pioneer to speak in NY on 20th Jan
The first clinical trials seeking to repair spinal cord injury on a pilot gr... is anticipated that the preparatory work to begin trials will be complete within two to three years. "For many years these injuries were considered incurable...Use of estrogen therapy may increase risk for gallbladder disease
...e two randomized, double-blind, placebo-controlled trials conducted at 40 U.S. clinical centers. The patien...sease outcomes. The researchers found that both trials showed greater risk of any gallbladder disease or surgery with estrogen: 67 percent increased risk w...Cogtest and NetMet join forces
...niversity School of Medicine, a leader in clinical trials for aging and dementia, and Chief Scientific Officer of NetMet; Dr. Thomas Crook, a pioneer in cognitive assessment and drug development, and Dr Tonmoy Sharma, a leading expert in schizophrenia and cognition. Net Met's Chief Operating Officer, Dr T...Penn researchers add more evidence to demonstrate role of COX inhibitors in heart-disease risk
...alled meta-analysis to combine the findings of two trials to obtain a stronger estimate of the risk of heart...pulation of CABG patients. Two placebo-controlled trials of Bextra and parecoxib (Dynastat) were performed in patients undergoing coronary artery bypass graf...Mayo Clinic recommends broadening treatment to battle recurrence of endometrial cancer
...ld potentially benefit from enrollment in clinical trials addressing the new target-based therapeutic approach." The new approach for treatment would be based on the inclusion of risk factors identified in previous studies and categorization of patients according to their risks for different patterns of rec...Study identifies predictors of HIV drug resistance in patients beginning triple therapy
...es is that they were limited to people in clinical trials and as people drop out they are lost to the study. In this study, we followed people beginning initial triple therapy for 30 months and were able to really get a sense of how the therapy works outside of clinical trials." Triple therapy for HIV/AIDS ...A site for sore eyes: New target for allergies found under the eyelid
...ules in the therapy of allergic diseases. Clinical trials are anticipated shortly and if they prove effective, these studies may lead to new therapies within the next 5 to 7 years."......ntration, although the results of large randomised trials to examine the efficacy and safety of this approac...d is beneficial or safe. Large randomised clinical trials of supplementation with folic acid, with or without vitamin B, will be necessary to test the therape...