Tag: "trials" at medical news

UCLA-VA study names India dietary staple as potential Alzheimer's weapon

...ase Research Center (ADRC) to begin human clinical trials to further evaluate its protective and therapeutic...rmation about enrolling in this and other clinical trials at the Center is available by calling (310) 206-3779 or online at http://www.npistat.com/adrc/Treat...

Non-narcotic treatment for migraines

...f the study, which involved reviewing data from 13 trials involving 655 adults, were published this month in the British Medical Journal. In studies comparing metoclopramide with placebos, the medication was 2.8 times more likely to provide significant reduction in migraine. In addition, combination treatme...

FDA approves Enablex for treatment of overactive bladder

... In total, Enablex has been studied in 98 clinical trials involving more than 10,000 people. In clinical trials, the most frequently reported adverse events associated with Enablex were dry mouth and constipation, however patient discontinuation rates due to these events were low. The majority of adverse ...

Genetically targeted therapies create opportunities to do business in new ways

...armacology and whose current research and clinical trials activities focus on breast cancer. Dr. Meslin is director of the Indiana University Center for Bioethics and previously served as Executive Director of the National Bioethics Advisory Commission....

Timing appears essential to combining antiangiogenesis and radiation therapy

Although the earliest clinical trials of the cancer-fighting potential of antiangiogenes...e dramatic results that some hoped for, subsequent trials showed that combining agents that suppress blood-vessel growth with therapies that destroy cancer ce...

Scientists identify protein critical to melanoma growth

...at the research results will soon lead to clinical trials of them in patients with melanoma. The study's lead author is Jinyan Du, PhD, who carried out the project while working as a student in Fisher's lab at Dana-Farber. Fisher is also a pediatric oncologist at Dana-Farber/Children's Hospital Cancer Care....

Guidelines for following pediatric cancer survivors aim to reduce medical complications

...00 investigators and conducts cooperative clinical trials nationwide. "The development of cures for most pediatric cancers has produced a growing population of childhood cancer survivors who are at increased risk for health problems caused by the therapies they underwent as children," Hudson said. "The nee...

Aspirin underused to reduce heart disease risk in diabetic women and young adults

...omen were not well represented in early randomized trials of aspirin for the prevention of initial cardiovascular disease events," Baker said. The low use of aspirin associated with younger age is also noteworthy, the authors said. "Physicians or patients may think that the risk of cardiovascular disease i...

Novartis announces collaboration with Bayer for EMSELEX

... by up to 77% versus placebo.1 Additional clinical trials comparing EMSELEX with placebo showed that EMSELEX... profile similar to placebo. To date, 98 clinical trials with EMSELEX have been completed involving more than 10,500 subjects and patients, of whom 7,146 wer...

NIH halts use of COX-2 inhibitor in large cancer prevention trial

...of this class of drug." "The rigor of our clinical trials system has allowed us to find this problem," said ...Institutional Review Boards (IRBs) for all related trials to assess the new information and to conduct a safety review as well...

Safety of childbirth after C-section examined

...us newborn complication is approximately 1 in 2000 trials of labor. At this level of risk, many women will c...rate has been fairly constant: 0.5 1.0 percent of trials of labor. The rate of VBAC fell by more than half to 10.6 percent in 2003. In addition, liability co...

How platelets help cancer invade other tissues

...gression and metastasis. However to date, clinical trials of the antiplatelet agents aspirin and heparin have yielded inconclusive, albeit promising, evidence that platelet inhibition may enhance the survival of cancer patients. One major reason for the difficulty in translating these results into effective...

Requip tablets treat symptoms of primary RLS

...67 patients, one of the largest placebo-controlled trials of a treatment for RLS conducted to-date, also showed significant improvements in sleep and quality of life in RLS patients taking Requip versus placebo. Requip is under review by the U.S. Food and Drug Administration (FDA) for the treatment of the ...

Researchers describe how human blood stem cells transform themselves to repair injured animal hearts

...m cells can help a heart heal," he adds. "Clinical trials that use bone marrow stem cells in people with heart damage have shown promise, but no one knows how it works. This starts to provide an explanation." Yeh and his research team, which includes investigators from the Texas Heart Institute, have been ...

ZYVOX(R) demonstrates high success rate for patients who develop MRSA surgical site infections

... reported adverse events in adults across clinical trials were nausea, headache, and diarrhea....

NHLBI statement on oral contraceptive study

...relationship to the findings from the WHI clinical trials of hormones, which showed that postmenopausal horm...ancer. In general, randomized controlled clinical trials provide the highest quality evidence to answer scientific questions. Analyses using baseline data, ...

Certain high blood pressure combination therapies elevate risk for death from cardiovascular disease

...erapy are consistent with the comparative clinical trials published thus far and support the current guidelines set forth in the report of the JNC 7 [Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure], which recommend low-dose diuretic therapy for most patien...

To help your mind, take steps to help your heart, study says

...e no data yet available from randomized controlled trials (the gold standard of clinical research) that included aspirin for vascular dementia. Also uncertain, the authors found, was evidence on the effect of complementary therapies vitamin E and ginkgo biloba, both often touted as helping m...

Success of experimental herpes vaccine builds momentum for human clinical trials

...us in order to induce an antibody response. But in trials of HSV-2 vaccines, a healthy antibody response has...rther strengthen the immune response. The clinical trials of previous herpes vaccines suggested that T cells as well as antibodies must be activated to launch...

Risks from labor after prior cesarean delivery low, study reports

...at term from uterine rupture was roughly 1 in 2000 trials of labor, said Mark B. Landon, M.D., of Ohio State University and the lead investigator for the NICHD Maternal-Fetal Medicine Units Network Cesarean Registry. Women who attempted vaginal birth after cesarean were also more likely to dev...

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