Tamoxifen's risks similar in African American and white women
...th early-stage primary breast cancer. However, the trials that demonstrated tamoxifen's benefits were done l...urgical Adjuvant Breast and Bowel Project clinical trials that had included more than 20,000 women. In women from both ethnic groups who had estrogen-recepto...Imatinib (Gleevec) has activity in AIDS-related Kaposi's sarcoma
... that the incidence of diarrhea was higher than in trials of patients with chronic myeloid leukemia receiving the same dose. Although the reason for the high degree of toxicity is unclear, researchers speculate that imatinib may interact with the medications involved in the HAART regimen, which can also cau...Small study shows SAMe may improve treatment of depression
...search Program, who led the study. "Some previous trials have suggested that SAMe might have effects compar...eful in treating depression, few rigorous research trials have been carried out. The current study was designed to investigate whether adding SAMe to antidep...Herpes virus offers new hope in curing cancer
...are responsive as well. Furthermore, some clinical trials for adult cancers have been launched," Dr. Cripe said. Existing treatments for neuroblastoma tumors include the surgical removal of the tumor, chemotherapy and radiation. In cases where the cancer has metastasized, blood and marrow transplants are co...Canadian researchers to develop 'smart drug' to repair psychiatric disorders
... and schizophrenia may be ready for early clinical trials within three years, with the launch of a $1.5 million project to take place at the Brain Research Centre (BRC), a partnership of the University of British Columbia and Vancouver Coastal Health Research Institute (VCHRI). The new drugs would be the fi...Testosterone patch will test FDA's decision making
...ch for sexy stories. None of the key clinical trials of Proctor & Gamble's testosterone patch have been published in peer reviewed journals, yet for a year or more excited media reports have sung the praises of the latest panacea for women's "low sex drive," writes author, Ray Moynihan, who recently wo...Female condoms overlooked in fight against spread of HIV/AIDS
...dom need to have a stronger voice, and large-scale trials of the device need to proceed as quickly as possible, moving beyond pilot and acceptability studies. As well, it is important to take a longer view of the female condom's benefit to society, Kaler said, noting that it took decades for positive change...FDA grants accelerated approval of TYSABRI, formerly antegren, for the treatment of MS
Phase III trials at one year demonstrate new level of efficacy 66%...antibodies. Analysis of the one-year Phase III MS trials indicate a low level of immunogenicity associated with TYSABRI. Patients were tested for antibodie...NSAIDs are of limited use for osteoarthritis
... osteoarthritis. Researchers in Norway analysed 23 trials to estimate the pain relieving effects of NSAIDs in patients with knee osteoarthritis. The final sample involved 10,845 patients, of whom 7767 received NSAIDs and 3078 received placebo. The analysis revealed that NSAIDs can reduce short term pain sli...Time to develop new antidotes for chemical attacks, urge researchers
... Yet no new antidotes have been tested in clinical trials in the last 30 years. An international collaboration is needed to make a concerted effort to develop and test new treatments that would benefit both groups of patients, write the authors. Atropine is currently the only clearly proved and moderately e...African children with HIV would benefit from daily doses of cheap antibiotic
...s the efficacy of drugs such as co-trimoxazole; no trials of this drug for HIV-infected adults or children have been done in areas with high levels of bacterial resistance to co-trimoxazole. Diana Gibb (Medical Research Council, UK) and colleagues studied 541 children with HIV symptoms aged between 1 and 1...HHS awards $10.4 million to fight AIDS on three continents
...PRA will form a foundation for successful clinical trials of treatments and vaccines needed in the battle against HIV/AIDS," he said. The awards announced today are A Cambodian Clinical Research Network for HIV and TB Awarded to: Cambodian Health Committee Phnom Penh, Cambodia Principal Investigator: S...Study emphasizes importance of women in cardiac research
...dy] has implications for the development of future trials and stresses the importance of making every effort to include women," said Dr. Andrea Russo, lead investigator of MUSTT. "As cardiovascular disease is the leading cause of death in both men and women, this also emphasizes the importance of ensuring ...Proposed addiction treatment successful, safe in second small trial
...aid Dr. Brodie. "We expect that the small clinical trials of GVG will lead to larger, placebo-controlled studies of this promising treatment." Drs. Dewy and Brodie have conducted extensive brain-imaging and behavioral studies on animals showing that GVG attenuates and, in some cases, blocks neuro...Data suggest ADDERALL XR significantly improved simulated driving in young adults with ADHD
...earch organization that conducts clinical research trials and provides consulting services to government agencies and to the pharmaceutical industry. At their Northwest Washington, DC facility WNI has conducted studies on antihistamines, anticholinergics, memory enhancement drugs, jet lag remedies, head tr...Capsules may be effective in treating bipolar disorder
...ess in San Diego are results from two of the first trials to use an extended-release form of carbamazepine c... H. Weisler, primary investigator of both clinical trials and adjunct professor of psychiatry at UNC's School of Medicine. "Many patients at present still e...Women taking breast enhancement pills swallow empty promises
..., there have been no scientifically sound clinical trials proving they work," said Thomas Lawrence, MD, Chair of the Plastic Surgery Educational Foundation (PSEF) Device and Technique Assessment Committee. Breast enhancement pills have become a lucrative industry in recent years due to their "guaranteed" s...An apple a day could protect against brain-cell damage
... were conducted in the laboratory, not in clinical trials with humans, he has no hesitation in recommending more apples in the diet as well as other fresh fruits and vegetables. "Indeed, I have a reason to say an apple a day keeps the doctor away," he says. The researchers used red delicious apples grown in...Chemoprevention backgrounder: Working for a future of cancer chemoprevention
...ted here, and some of the efforts involve national trials being led by M. D. Anderson researchers. Those com...revention study. The funds pay for chemoprevention trials as well as parallel genetic, molecular and pharmacologic studies in the lab, says Hong, all aimed at...NIH launches new study to compare prostate surgery and drugs
...d patients," said John W. Kusek, Ph.D., a clinical trials expert at NIDDK. MIST therapies are approv...here have been few rigorously conducted randomized trials of the minimally invasive surgical approaches. "Previous studies of TUMT and TUNA haven't...