Shark-Liver Substance May Slow Growth Of Brain Tumors
...dishes containing human, rabbit or rat solid brain tumor cells. The blood vessel cells' rate of growth fell by up to 83 percent after two days, while the tumor cells treated with squalamine were unaffected. Results of a second study showed that time-release ca...Drug And Radiation Treatment May Shrink Pancreatic And Gastric Tumors
...ubstantial activity in thepatients. The result was tumor reduction in 70 percent of the patients withstomac.... According to study leader Howard Safran, M.D., tumor regression occurredrapidly in certain patients, often within three weeks after treatments began.Afte...... after doctors gave up on William Hines,his kidney tumor is gone and his life is back to normal. Hines is o... guides the tip of the probe into the heart of the tumor using magnetic resonance imaging (MRI) techniques designed in the laboratory of biomedical engineer ......s patientscan tolerate. But the aminopterin made a tumor in Cofield's liver disappear. "I didn't...n underwent chemotherapy, but tests soon showedthe tumor had spread to her liver. Dr. David Scott Miller, an associate professor of obstetrics andgyn...Targeted Protein Toxin Effective Against Persistent Brain Tumors
...sferrin that targets rapidly growing cells such as tumor cells. Nine ofthe 15 patients who were evaluated...his treatment had reductions in tumorsize, and the tumor disappeared completely in two patients. While these resultsare promising, much more work remains be...Penn Researchers Initiate Ground-Breaking New Trials To Treat
... the tissue to stimulatethe drug -- destroying the tumor cells by exposing them to anactivated form of oxygen. In these cases, PDT is utilized aftersurgery to help eradicate any remaining cancer cells. Through innovative combination treatments, Penn researchers areexploring new protocols and offering alte...Targon And Duke Cancer Center Sign $3.75 Million Agreement To Produce Advanced Anti-Cancer Drugs
...new drugs. Since traditional anti-tumor drugs kill tumor cells, we expect to see them killing cancer cells ...ounds that interrupt other pathways may not kill a tumor immediately, but rather cause it to shrink over time. Theendpoint of such treatment is harder to jud......ng the same plane, theradiation beams aimed at the tumor also hit the lungs, causing further damage,"Folz said. Physicians have known about another toxicity to lungs from high-dosechemotherapy and BMT, called idiopathic pulmonary syndrome (IPS), which occursmuch sooner in cancer treatment, is mo...Penn Researchers Create Drug To Help Target Attack On Cancerous Tumors
...ring this time, EF5 attaches or "binds" to hypoxic tumor cells, but "washes out" of tumor regions that are oxygen-rich. A small portion of the tumor, removed at surgery, is then exposed to f...Radio Frequencies Used To Kill Inoperable Liver Tumors At Penn's Cancer Center
...by a microwave oven--kills the tumor. Once all the tumor cellsare dead, the body absorbs this tissue over time and no resectionof the tumor is needed. In a recently approved protocol, Penn's cancer specialists are studying the effec......or activity. It also showed, forexample, complete tumor remissions increased from 13% (with a 50% mortality ratedue to cisplatin toxicity) in cisplatin only treated subjects to a 63% completeremission rate with no mortality or toxicity in subjects pretreated with BNP7787prior to the same toxic dose of cis...Successful Cancer Therapy May Doom Later Treatments To Failure
...earchers found that pore size varied among the six tumor types -- forexample, mouse breast tumors had much .... "Nobody had measured resistance to blood flow in tumor vessels before. It was like walking into a wide open field," he says. Jain and his colleagues showed...Area of Research Outlined For Promising New Cancer Drugs
...regulatingangiongenesis in other processes besides tumor growth is one area of researchthat requires additi...pear. In mice, the drugs appear to stop malignant tumor growth andspreading, but they have not yet been tested in humans, and the medicalcommunity remains c...ONYX Pharmaceuticals Reports Phase II Clinical Trial Results At ASCO Meeting
...ten patients with recurrenttumors have experienced tumor regressions of greater than 50 percent to date,wit...atients treated withONYX-015 alone had significant tumor regressions, including two completeregressions in patients with end-stage, treatment-resistant disea...Wistar Scientist Awarded American Cancer Society Grant For Study Of Tumor Suppressor Proteins
...16INK4 protein does notinterfere as it should with tumor growth. "Because of its key role in the development of tumors," explains Dr.Marmorstein, "the CDK4 protein is an excellent target for anti-cancertherapies." His laboratory's findings on the structural properties of theP16INK4 protein are expected ...New Treatment Targets Most Malignant Brain Tumors
...h the careful surgical removal of a patient's main tumor mass by AllanFriedman, professor of surgery and ch... While such surgery usually excises the main tumor mass, it cannot removethe cancer cells around the tumor that have infiltrated normal brain tissue. N...New Radiation Procedure Targets Liver Malignancies
... along with chemotherapy delivered directly to the tumor via the hepatic artery. As a result of that resea...egy works, McGinn says, by carefully targeting the tumor with external beam irradiation and excluding as much healthy liver tissue as possible. For each pat...Brain Tumor Treatment In Multicenter Tests
...ding to Ewend, about 20,000 cases of primary brain tumor occur eachyear in the U.S. compared to about 50,00...he brain poorly,increasing the likelihood of brain tumor relapse," he explains. "In order to getchemotherapy into the brain, you have to choose drugs that ha...New Study Designed To Improve Outcomes In Women With Metastatic Breast Cancer
...ulate an immune response, we will destroy residual tumor cells thatremained following chemotherapy." Foon a... of Medicine, the vaccine mimics aprotein found on tumor cell surfaces in order to stimulate an immune response inthe body. The patient's body is una...Scientists Report Cancer Fighting Drug As Possible Treatment For Multiple Sclerosis
... in the autoimmune process damaging the CNS in MS: tumor necrosisfactor-a (TNF-a), Fas-ligand (FasL) and interleukin-4 (IL-4). TNF-a and FasL aretoxic to CNS myelin and to the myelin-producing brain cells calledoligodendrocytes, which are a prime target of the immune attack in MS. IL-4 isconsidered to be a...