Scientists stalk PPAR-gamma, find novel cancer connection
...niversity of Rochester researchers found that this type of cancer expresses a protein that makes it an eas... destroyed. PPAR-ligands are emerging as a new type of cancer therapy because they directly target errant cells and stop tumor growth, at least in anima...Add an 'E' to the alphabet for identifying melanoma
...hange in appearance. This is especially true for a type of melanoma called nodular that doesn't fit neatly into the ABCD criteria, explains David Polsky, M.D., Ph.D., a dermatologist and one of the authors of the new report. Dr. Polsky is Associate Director of the NYU Department of Dermatology's Pigmented...Magnetic resonance imaging helps detect breast cancer but does not eliminate need for biopsy
... affected by factors such as breast density, tumor type or menopausal status, which frequently complicates mammographic interpretations." Bluemky believes MRI will be most beneficial for patients with difficult to interpret mammograms....Bulimic teens also likely to suffer from depression
...to overcome. The binges and purges that serve as a type of coping mechanism in the beginning of the disorder may, over time, lose their comforting aspects while their harmful ones continue to be amplified. This, in turn, may cause the intensity of the depression to increase, making the occurrence of major...Lab study: Protein delivered via genetically engineered virus slowed glioblasoma multiforme growth
...al drug, gancyclovir. In laboratory studies, this type of gene therapy has proved almost 100 percent effective. But in clinical trials, it has had limited effectiveness, suggesting that the virus is not able to deliver the suicide gene effectively into a large tumor mass. "Importantly, results from t...New marrow transplant method developed at Stanford may eliminate fatal side effects
...ntails adjusting the patient's level of a specific type of immune cell, the regulatory T cells, before the transplant is done. The method was first developed in mice by Samuel Strober, MD, professor of medicine (immunology and rheumatology), who has been studying these types of cells for more than 25 year...Blacks and poor more likely to donate than receive many types of transplant organs
...en desirable. For example, ensuring a good tissue type match improves survival of transplanted organs but may make it harder for blacks to receive organs. Disparities that are both avoidable and undesirable are more concerning. For example, lack of health insurance may act as a barrier to transplantati...Choosing the kind of fat to avoid obesity
The type of fat ingested may create the conditions for or, on the other hand, prevent the development of obesity. This is the conclusion drawn by Patricia Prez Matute, PhD student at the Department of Physiology and Nutrition at the University of Navarre in h...Endocrine Society calls for clinical guidelines on androgens for women
...s related to androgen therapy in women include the type of treatment, risks and clinical monitoring of responses. While women have previously been prescribed testosterone in several forms including oral, buccal, transdermal and injectable, prior research on testosterone therapy in women has been done wit...VGTI researchers help uncover why aging reduces immune system function
...total CD8 population. The accumulation of this one type of cell takes away valuable space from other cells, resulting in an immune system that is less diverse and thus less capable in effectively locating and eliminating pathogens. To conduct the research, scientists at the VGTI studied mice, which h...New research tool aids study of national well-being
...ely, if our survey is successful and generates the type of data we hope, we would like to see the governme...ctives to the study of well-being," he said. "This type of work could not have been done without collaboration across disciplines." ...Nerve damage from alcoholism reversed after liver transplantation
...ts are usually not performed on patients with this type of complication because it is thought to be irreversible, although to date, very few studies have been conducted to verify this assertion. Despite the patient's poor prognosis and continued deterioration, he underwent a liver transplant in Decemb...New drug protects against the hardening of arteries
...evels (such as cholesterol and triglycerides), and type 2 diabetes, respectively. The presence of PPARs in...nist rosiglitazone that is currently used to treat type 2 diabetes. GW7647 also reduced weight gain, and insulin and lipoprotein levels. In contrast, lesion...Stem cells to the rescue - or not?
...al stem cells, capable of developing into any cell type of the body, to injured tissue in order to effect repair. A subset of bone marrow cells, called bone marrowderived side population (BM-SP) cells, make up only 0.01-0.05% of whole bone marrow. In mice, these cells have previously been reported to rest...Jefferson scientists use gene therapy to rescue failing hearts in animals
...therapy since most of the previous studies of this type are aimed at prevention giving a gene and showing that certain heart problems are prevented. In those cases, heart problems are not actually reversed. This is a remarkable rescue and reversal of cardiac dysfunction, with obvious clinical implication...Diagnostic imaging surge by non-radiologists draws concern
... members of their own medical group, represent the type of trend that will bankrupt the healthcare system by driving up costs overall," said David C. Levin, M.D., author or co-author of five papers presented today at the annual meeting of the Radiological Society of North America (RSNA). "Plus, having ph...Simple intervention nearly eliminates catheter-related bloodstream infections
...ing to a study by Johns Hopkins researchers. "This type of improvement has never been demonstrated, but there is no reason that ICU's across the country can't implement these interventions to achieve similar results," said Sean Berenholtz, M.D., M.H.S., assistant professor of anesthesiology and critical c...Brain imaging with MRI could replace lie detector
...s a vital approach to understand this very complex type of cognitive behavior," Dr. Faro said. "The real-life stimulus is critical if this technique is to be developed into a practical test of deception." Because physiologic responses can vary among individuals and, in some cases, can be regulated, the po...Canadian researchers to develop 'smart drug' to repair psychiatric disorders
...as that need to be repaired," says Wang. "This new type of drug will correct abnormal brain functions in a...llular level, the team will test their design of a type of drug that can fine-tune communication between brain cells and bring excitatory and inhibitory act...... production appears to be a common complication of type 2 diabetes in men, affecting 1 out of 3 diabetic p... a whole new story on the crucial complications of type 2 diabetes," said Paresh Dandona, M.D., senior author on the study and director of the Division of E...