Mayo Clinic discovers 'new pathway' against pancreatic cancer
...ive years of diagnosis Despite recent advances in understanding how cancers work at the molecular level, pancreatic cancer lacks an effective treatment. Approximately 30,000 Americans are diagnosed with pancreatic cancer annually, and the disease kills the same number each year. Ninety percent of these cancers a...New ways to design safer & more effective topical (transdermal) drug delivery announced in the PNAS
...sign of the new CPEs was based on the researchers' understanding of the molecular forces that are associated with CPE safety and potency. They then screened the new CPEs, first using computer technology and then testing the most promising ones in the laboratory environment. The molecules identified broaden the num...Neuronal death and processing of Tau protein in Alzheimer's disease
...of tau fragments; such finding has no relevance in understanding the molecular pathogenesis of FTDP-17. However, since the mutation is located in a region important for the affinity to microtubules, this observation suggests that this region is likely to be involved in the apoptotic properties of tau. These result...Researchers say breast cancer in Africa may provide clues to the disease in African-Americans
...s of breast cancer in sub-Saharan Africa. They say understanding the breast cancer burden and clinical characterist...n trace their ancestry from, may contribute to the understanding of racial factors in breast cancer. The review found current literature, while incomplete, particula...Brain imaging studies investigate pain reduction by hypnosis
...nswers. "Imaging studies like this one improve our understanding of what might be going on and help researchers ask even more specific questions aimed at identifying the underlying mechanism," Schulz-Stubner said. "It is one piece of the puzzle that moves us a little closer to a final answer for how hypnosis reall...Bevacizumab combined with chemotherapy prolongs survival for some patients with advanced lung cancer
...nd survival of cancer cells. It is through better understanding of these molecular processes that significant advances will be made in the treatment of this disease." An estimated 172,570 people will be diagnosed with lung cancer in the United States in 2005. Lung cancer is the second most commonly diagnosed can...Chemicals in tattoo inks need closer scrutiny
...young people, it is vital that we develop a better understanding of this form of self expression." The new research...eactions might be, and the only way to gain better understanding is to know what chemicals make up the inks, the researchers say. Finley-Jones and Wagner expect that...Philanthropist Paul F. Glenn launches labs for aging research at Harvard Medical School
...t relationships with other institutions focused on understanding the molecular biology of aging and mechanisms that... costs and increasing the productive lifespan. By understanding the basic mechanisms of aging, we hope to altogether avoid or mitigate the onset of age related dise...Growing your own replacement teeth? Not science fiction!
...gy. Advances in stem cell biology will improve our understanding of degenerative diseases and assist in developing therapies for replacing damaged or diseased parts/tissues. During the 83rd General Session of the International Association for Dental Research, convening today at the Baltimore Convention Center, sev...2005 Research in Dental Caries Award
...ve achievements that have contributed to the basic understanding of caries etiology and/or to the prevention of dental caries. Professor Kidd has been involved with dental research and teaching for over 30 years. She started her research career with studies on model systems to better understand aspects of the dent......s. Dr. Eliades has made important contributions to understanding molecular interactions and conformational changes of collagen with dentin-bonding agents. His work is an essential and fundamental counterpart to the electron microscopic analyses of the hybrid layer, which have received so much deserved attention. D...2005 Research in Oral Biology Award
...ognizes Dr. Somerman's outstanding contribution to understanding of the physiology and pathology of the mineralized and soft tissues of the peridontium. She has published widely, currently serves on four journal editorial boards, and has long been committed to serving on research review bodies, AADR panels, and in...2005 Pulp Biology Research Award
...ributions of Professor Magloire have increased our understanding about the phenotypic characteristics of odontoblasts. His research has advanced the field of Pulp Biology.......ve achievements that have contributed to the basic understanding of salivary gland structure, secretion, and functi...s that have had a highly significant impact on our understanding of the molecular mechanisms of exocytosis. These include analysis of secretory granules and their me...Common anesthetics appear safe for developing fetal brain
...These findings are an important step toward better understanding this issue, the researchers said, since a study in...nesthetic exposure, as well as developing a better understanding of the combined effects of anesthesia and surgical manipulation on physiological changes in the fetu...Tobacco industry pays scientists to challenge secondhand smoke's link to infant death risk
...f secondhand smoke exposure. "Undermining people's understanding of the link between secondhand smoke and SIDS places infants everywhere at increased risk," according to Stanton Glantz, PhD, director of the Center for Tobacco Control Research and Education at UCSF and senior author of the new study analyzing the t...English-speaking Hispanic youth more likely to have sex early
...r visits to health care professionals." "A greater understanding of the healthy immigrant effect has the potential ...t powerful argument for why we must gain a greater understanding of the influence of acculturation on children's health." (Arch Pediatr Adolesc Med. 2005; 159:295-29...Study: Two brain systems regulate how we call for help
...umans, Kalin says, and may provide a framework for understanding differences in emotional expressivity. "People who are less secure and more sensitive to potential threat are likely to have increased amygdala activity that may inhibit their urge to ask for help, which is related to right prefrontal cortex activity...Serum sodium level is a major predictor of a poor prognosis for heart failure patients
.... Now, we think it can be treated, and we have an understanding that treating it can make a huge difference for the patient," says Dr. Gheorghiade. Sodium is an electrolyte that helps with nerve and muscle function, and also helps to maintain blood pressure. Hyponatremia most commonly occurs in people whose ki...University of Manchester awarded 826k for brain science and mental health research
...tion and will make a significant difference to our understanding and treatment of stroke, dementia and mental illness." The call for research proposals followed two themes: 'Pathfinders', to develop novel and exciting research ideas for laboratory and population-based studies, and 'Trial Platforms' to build capaci...